CYCLOBUTYL-ACETIC ACID

Uses

Product Name: CYCLOBUTYL-ACETIC ACID
CAS No.: 6540-33-6
Chemical Name: CYCLOBUTYL-ACETIC ACID
Synonyms: Cyclobutyl;CYCLOBUTYL-ACETIC ACID;2-cyclobutylacetic acid;cyclobutylacetic acid(SALTDATA: FREE)
CBNumber: CB0731478
Molecular Formula: C6H10O2
Formula Weight: 114.14
MOL File: 6540-33-6.mol

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CYCLOBUTYL-ACETIC ACID Property

Boiling point:: 212-213.5℃ (768 Torr)
Density: 1.0131 g/cm3(Temp: 18.5 °C)
refractive index: 1.4475 (589.3 nm 18.5℃)
storage temp.: 2-8°C
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
pka: 4.85±0.10(Predicted)
color: Colourless

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
HazardClass: IRRITANT
HS Code: 2902900000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C3784
Product name: 2-Cyclobutylacetic Acid
Purity: min. 95.0 %
Packaging: 1G
Price: $119
Updated: 2025/07/31

TCI Chemical

Product number: C3784
Product name: 2-Cyclobutylacetic Acid
Purity: min. 95.0 %
Packaging: 5G
Price: $427
Updated: 2025/07/31

TRC

Product number: C989393
Product name: Cyclobutyl-aceticacid
Packaging: 500mg
Price: $130
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC120167
Product name: Cyclobutylacetic acid
Packaging: 100mg
Price: $72
Updated: 2021/12/16

Matrix Scientific

Product number: 061113
Product name: Cyclobutylacetic acid
Packaging: 1g
Price: $80
Updated: 2021/12/16

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CYCLOBUTYL-ACETIC ACID Chemical Properties,Usage,Production

Uses

Cyclobutylacetic acid is a carboxylic acid organic compound, often used as an intermediate or precursor in chemical synthesis and pharmaceutical research.

Synthesis

4426-03-3

6540-33-6

Step 2: 2-Cyclobutylacetonitrile (15.00 g, 157.66 mmol, 1.00 eq.) was dissolved in 6 M hydrochloric acid (150 mL, 5.71 eq.) and the reaction was stirred for 16 hours at 120 °C. After completion of the reaction, the mixture was diluted with distilled water (500 mL) and extracted with ethyl acetate (200 mL x 2). The organic phases were combined and washed with distilled water (400 mL). The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure to give 2-cyclobutylacetic acid (16.00 g, 140.18 mmol, 88.9% yield) as a colorless liquid. NMR hydrogen spectrum (CDCl3, 400MHz) δ: 2.69-2.68 (m, 1H), 2.47-2.45 (m, 2H), 2.17-2.15 (m, 2H), 1.89-1.87 (m, 2H), 1.75-1.70 (m, 2H).

References

[1] Patent: WO2017/21969, 2017, A1. Location in patent: Page/Page column 62; 54
[2] Journal of medicinal chemistry, 1963, vol. 6, p. 221 - 227
[3] Molecular Crystals and Liquid Crystals (1969-1991), 1989, vol. 168, p. 229 - 246
[4] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 18, p. 4715 - 4722
[5] Journal of the American Chemical Society, 1994, vol. 116, # 19, p. 8843 - 8844

CYCLOBUTYL-ACETIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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CYCLOBUTYL-ACETIC ACID Suppliers

China 79 France 1 Germany 1 India 1 Switzerland 1 United Kingdom 3 United States 15 Global 101

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
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Fax: 86-025-86918232
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Energy Chemical

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Email: sales8178@energy-chemical.com
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Email: sales@accelachem.com
Country: China
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Shanghai Hanhong Scientific Co.,Ltd.

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Email: info@hanhongsci.com
Country: China
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Shanghai Sunway Pharmaceutical Technology Co., Ltd

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Atop-Pharma (Shanghai) Technology Co., Ltd.

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Shanghai Raise Chemical Technology Co.,Ltd

Tel: +86-021-50935922
Fax: +86-021-33847795
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View Lastest Price from CYCLOBUTYL-ACETIC ACID manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: CYCLOBUTYL-ACETIC ACID 6540-33-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-14

Career Henan Chemical Co

Product: CYCLOBUTYL-ACETIC ACID 6540-33-6
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-09

6540-33-6, CYCLOBUTYL-ACETIC ACIDRelated Search:

Cyclobutylamine tert-butyl cyclopropanecarboxylate Cyclopropylboronic acid Methyl cyclopropane carboxylate Sulfolane Cyclobutanecarboxylic acid Cyclobutanemethanol Cyclobutanecarbonitrile Cyclobutanol Cyclobutanone PINONIC ACID DIMETHYL 1,4-CUBANEDICARBOXYLATE (R)-TERT-BUTOXYCARBONYLAMINO-CYCLOBUTYL-ACETIC ACID (S)-TERT-BUTOXYCARBONYLAMINO-CYCLOBUTYL-ACETIC ACID 4-[(FURAN-2-YLMETHYL)-CARBAMOYL]-1,2,2-TRIMETHYL-SPIRO[2.3]HEXANE-1-CARBOXYLIC ACID CYCLOBUTYL-ACETIC ACID METHYL ESTER 1-(CARBOXYMETHYL)-2,2,3,3-TETRAFLUOROCYCLOBUTANECARBOXYLIC ACID pinic acid

cyclobutylacetic acid(SALTDATA: FREE)

2-cyclobutylacetic acid

CYCLOBUTYL-ACETIC ACID

Cyclobutyl

6540-33-6

pharmacetical