4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE
- Product Name
- 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE
- CAS No.
- 80745-07-9
- Chemical Name
- 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE
- Synonyms
- MTR-CL;MTR CHLORIDE;4-METHOXY-2,3,6-TRIMETHYLBENZENE-;4-Methoxy-2,3,6-trimethylphenylaulfomyl chloride;4-METHOXY-2,3,6-TRIMETHYLPHENYLSULFONYL CHLORIDE;4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE;4-METHOXY-2,3,6-TRIMETHYLBENZENESULPHONYL CHLORIDE;Benzenesulfonyl chloride, 4-methoxy-2,3,6-trimethyl-;4-METHOXY-2,3,6-TRIMETHYLBENZENE-SULFONYL CHLORIDE 97+%;Benzenesulfonyl chloride, 4-methoxy-2,3,6-trimethyl- (9CI)
- CBNumber
- CB0732743
- Molecular Formula
- C10H13ClO3S
- Formula Weight
- 248.73
- MOL File
- 80745-07-9.mol
4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE Property
- Melting point:
- 57-61 °C
- Boiling point:
- 372.5±42.0 °C(Predicted)
- Density
- 1.250±0.06 g/cm3(Predicted)
- storage temp.
- -20°C
- Sensitive
- Moisture Sensitive
- BRN
- 4867665
- CAS DataBase Reference
- 80745-07-9(CAS DataBase Reference)
Safety
- Hazard Codes
- C
- Risk Statements
- 34
- Safety Statements
- 26-36/37/39-45
- RIDADR
- UN 3261 8/PG 3
- WGK Germany
- 3
- F
- 3-10-21
- HazardClass
- 8
- PackingGroup
- II
- HS Code
- 29093090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H314Causes severe skin burns and eye damage
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P363Wash contaminated clothing before reuse.
N-Bromosuccinimide Price
- Product number
- 65373
- Product name
- 4-Methoxy-2,3,6-trimethylbenzenesulfonyl chloride
- Purity
- ≥95.0% (HPLC)
- Packaging
- 10G
- Price
- $407
- Updated
- 2023/01/07
- Product number
- 6762-5-21
- Product name
- 4-Methoxy-2,3,6-trimethylbenzenesulfonyl chloride
- Purity
- 95%
- Packaging
- 1g
- Price
- $98
- Updated
- 2021/12/16
- Product number
- 2755AL
- Product name
- 4-Methoxy-2,3,6-trimethylbenzenesulfonylchloride,tech.
- Packaging
- 1g
- Price
- $147
- Updated
- 2021/12/16
- Product number
- 2755AL
- Product name
- 4-Methoxy-2,3,6-trimethylbenzenesulfonylchloride,tech.
- Packaging
- 5g
- Price
- $344
- Updated
- 2021/12/16
- Product number
- 2755AL
- Product name
- 4-Methoxy-2,3,6-trimethylbenzenesulfonylchloride,tech.
- Packaging
- 25g
- Price
- $882
- Updated
- 2021/12/16
4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE Chemical Properties,Usage,Production
Uses
peptide synthesis
Synthesis
20469-61-8
80745-07-9
(2) Synthesis of 4-methoxy-2,3,6-trimethylbenzenesulfonyl chloride: 4.5 g of 2,3,5-trimethylanisole was dissolved in 500 mL of dichloromethane and the reaction system was cooled to -5 °C to -10 °C. The reaction system was then cooled to -5 °C to -10 °C. The reaction system was then cooled to -5 °C to -10 °C. Subsequently, 6.0 mL of a dichloromethane solution of chlorosulfonic acid (400 mL) was added slowly and dropwise. After completion of the reaction mixture with stirring at room temperature, the reaction was quenched by pouring it into an ice-5% aqueous NaHCO3 solution. The organic phase was separated and the aqueous phase was extracted with dichloromethane. The organic layers were combined, washed with water and dried with anhydrous magnesium sulfate. The solvent was removed by distillation under reduced pressure and the residue was recrystallized by hexane and filtered to give white crystals. Yield 5.0 g (yield 67.0%), melting point 56°C-58°C. Elemental analysis (C10H13O3SCl) Calculated values: C, 48.29; H, 5.27; S, 12.89; Cl, 14.26; Measured values: C, 48.42; H, 5.21; S, 12.61; Cl, 14.25.
References
[1] Chemical & Pharmaceutical Bulletin, 1981, vol. 29, # 10, p. 2825 - 2831
[2] Tetrahedron Letters, 2007, vol. 48, # 8, p. 1337 - 1340
[3] Patent: US4368150, 1983, A
[4] Patent: US4476051, 1984, A
4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE Suppliers
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- Country
- Switzerland
- ProdList
- 6896
- Advantage
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View Lastest Price from 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE manufacturers
- Product
- 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE 80745-07-9
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-08-11
- Product
- 4-METHOXY-2,3,6-TRIMETHYLBENZENESULFONYL CHLORIDE 80745-07-9
- Price
- US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1000kg
- Release date
- 2020-01-13