NETROPSIN
- Product Name
- NETROPSIN
- CAS No.
- 1438-30-8
- Chemical Name
- NETROPSIN
- Synonyms
- f6;t1384;k-117;ia887;2814-a;Fusitin;NCI 3067;NSC 3067;ch-777-a;NETROPSIN
- CBNumber
- CB0734505
- Molecular Formula
- C18H26N10O3
- Formula Weight
- 430.46
- MOL File
- 1438-30-8.mol
NETROPSIN Property
- Melting point:
- 171-173℃
- Boiling point:
- 544.74°C (rough estimate)
- Density
- 1.3374 (rough estimate)
- refractive index
- 1.6500 (estimate)
- storage temp.
- −20°C
- solubility
- H2O: 1 mg/mL
- form
- powder
- pka
- 14.37±0.70(Predicted)
- color
- faint yellow
- EPA Substance Registry System
- Netropsin (1438-30-8)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H301Toxic if swalloed
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P405Store locked up.
P501Dispose of contents/container to..…
NETROPSIN Chemical Properties,Usage,Production
Uses
Netropsin dihydrochloride is a small-molecule MGB (minor-groove binder) and antibiotic, inhibits the catalytic activity of isolated topoisomerase and interferes with the stabilization of the cleavable complexes of topoisomerase II and I in nuclei. Netropsin dihydrochloride has antibacterial and antiviral activity[1][2].
References
[1] Beerman TA et al. Netropsin and bis-netropsin analogs as inhibitors of the catalytic activity of mammalian DNA topoisomerase II and topoisomerase cleavable complexes. Biochim Biophys Acta. 1991 Aug 27;1090(1):52-60. DOI:10.1016/0167-4781(91)90036-l
[2] Finlay A C, et al. Netropsin, a new antibiotic produced by a Streptomyces. Journal of the American Chemical Society, 1951, 73(1): 341-343.
NETROPSIN Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from NETROPSIN manufacturers
- Product
- NETROPSIN 1438-30-8
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2025-03-14
- Product
- NETROPSIN 1438-30-8
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%HPLC
- Supply Ability
- 200KG
- Release date
- 2020-02-01