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Monensin

Product Name
Monensin
CAS No.
17090-79-8
Chemical Name
Monensin
Synonyms
MONENSIN SODIUM;a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid
CBNumber
CB9748019
Molecular Formula
C36H62O11
Formula Weight
670.87
MOL File
17090-79-8.mol
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Monensin Property

Melting point:
103-105°C
alpha 
D +47.7°
Boiling point:
608.24°C (rough estimate)
Density 
1.0773 (rough estimate)
refractive index 
1.5465 (estimate)
storage temp. 
2-8°C
pka
6.6 (in 66% DMF)
CAS DataBase Reference
17090-79-8(CAS DataBase Reference)
EPA Substance Registry System
Monensin (17090-79-8)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
36/37/39-45
WGK Germany 
3
RTECS 
JH2830000
Hazardous Substances Data
17090-79-8(Hazardous Substances Data)
Toxicity
LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological
Product number
M4900-01
Product name
Monensin A
Packaging
5mg
Price
$362
Updated
2021/12/16
Usbiological
Product number
M4435-02
Product name
Monensin
Packaging
500ul
Price
$393
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593405
Product name
Monensin
Packaging
50μg
Price
$425
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0008060
Product name
MONENSIN
Purity
95.00%
Packaging
5MG
Price
$497.06
Updated
2021/12/16
Biorbyt Ltd
Product number
orb593405
Product name
Monensin
Packaging
100μg
Price
$635.8
Updated
2021/12/16
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Monensin Chemical Properties,Usage,Production

Description

Monensin was found in the mycelium of Streptomyces cinnamonensis by Eli Lilly & Co. in 1967 in the course of screening for anticoccidial and growth-promoting substances for cattle, swine, and chickens. It shows antiprotozoal, antibacterial, and antifungal activities, as well as anticoccidial activity. Monensin is widely used to treat such infections and as a feed additive to promote the growth of livestock.

Chemical Properties

Crystallin Solid

Uses

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.

Uses

Poliether antibiotic. Coccidiostat

Uses

Monensin (2) C36H62O11, a carboxylic acid which is used as its water-soluble sodium salt (Coban, Rumensin). Monensin is also used to treat histomoniasis. The polyether ionophoric antibiotics are capable of complexing and interfacing with specific alkali metal cations to render them lipid-soluble and diffusible across parasite mitochondrial membranes. Related useful polyether antibiotics are narasin and lasalocid (3, Lasalocid A, C34H54O8,).

Definition

ChEBI: Monensin A is a spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. It has a role as a coccidiostat, an antifungal agent and an ionophore. It is a monocarboxylic acid, a cyclic hemiketal, a spiroketal and a polyether antibiotic.

brand name

Coban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).

Safety Profile

Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Monensin Preparation Products And Raw materials

Raw materials

Preparation Products

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Monensin Suppliers

3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15839
Advantage
69
Sichuan Kulinan Technology Co., Ltd
Tel
400-1166-196 18981987031
Fax
028-84555506 800101999
Email
cdhxsj@163.com
Country
China
ProdList
11707
Advantage
57
TargetMol Chemicals Inc.
Tel
021-021-33632979 15002134094
Fax
021-33632979
Email
marketing@targetmol.com
Country
China
ProdList
7783
Advantage
58
Finetech Industry Limited
Tel
027-87465837 19945049750
Fax
027-8777-2287
Email
sales@finetechnology-ind.com
Country
China
ProdList
9648
Advantage
58
Suzhou yacoo science co.,Ltd
Tel
0512-87182056 18013166090
Fax
0512-87182056
Email
lingling.qi@yacoo.com.cn
Country
China
ProdList
7295
Advantage
60
Wuhan Dahua Weiye Pharmaceutical Chemical Co., Ltd.
Tel
027-59420981,18702770802
Fax
027-83322098
Country
China
ProdList
1975
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16684
Advantage
50
Hubei Jusheng Technology Co.,Ltd
Tel
027-59599241 18871490274
Fax
027-59599241
Email
1400878000@qq.com
Country
China
ProdList
9958
Advantage
58
Codow Chemical Co.,Ltd.
Tel
18620099427
Fax
+86-20-62619665
Email
amy@howeipharm.com
Country
China
ProdList
17687
Advantage
55
Shanghai QianYan Bio-technology Co., Ltd
Tel
02781293128
Email
orders@biochemsafebuy.com
Country
China
ProdList
9923
Advantage
55
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View Lastest Price from Monensin manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.
Product
Monensin 17090-79-8
Price
US $0.00/kg
Min. Order
25kg
Purity
99.0%
Supply Ability
10tons
Release date
2024-04-29
shandong perfect biotechnology co.ltd
Product
Monensin 17090-79-8
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
100KG
Release date
2023-08-09
Hebei Yanxi Chemical Co., Ltd.
Product
Monensin 17090-79-8
Price
US $0.00/kg
Min. Order
1kg
Purity
90.00%
Supply Ability
20tons
Release date
2023-09-25

17090-79-8, MonensinRelated Search:


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