Monensin

ChemicalBook > CAS DataBase List > Monensin

Product Name: Monensin
CAS No.: 17090-79-8
Chemical Name: Monensin
Synonyms: MONENSIN SODIUM;a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid
CBNumber: CB9748019
Molecular Formula: C36H62O11
Formula Weight: 670.87
MOL File: 17090-79-8.mol

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Monensin Property

Melting point:: 103-105°C
alpha: D +47.7°
Boiling point:: 608.24°C (rough estimate)
Density: 1.0773 (rough estimate)
refractive index: 1.5465 (estimate)
storage temp.: 2-8°C
pka: 6.6 (in 66% DMF)
CAS DataBase Reference: 17090-79-8(CAS DataBase Reference)
EPA Substance Registry System: Monensin (17090-79-8)

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 36/37/39-45
WGK Germany: 3
RTECS: JH2830000
Hazardous Substances Data: 17090-79-8(Hazardous Substances Data)
Toxicity: LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Usbiological

Product number: M4900-01
Product name: Monensin A
Packaging: 5mg
Price: $362
Updated: 2021/12/16

Usbiological

Product number: M4435-02
Product name: Monensin
Packaging: 500ul
Price: $393
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb593405
Product name: Monensin
Packaging: 50μg
Price: $425
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0008060
Product name: MONENSIN
Purity: 95.00%
Packaging: 5MG
Price: $497.06
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb593405
Product name: Monensin
Packaging: 100μg
Price: $635.8
Updated: 2021/12/16

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Monensin Chemical Properties,Usage,Production

Description

Monensin was found in the mycelium of Streptomyces cinnamonensis by Eli Lilly & Co. in 1967 in the course of screening for anticoccidial and growth-promoting substances for cattle, swine, and chickens. It shows antiprotozoal, antibacterial, and antifungal activities, as well as anticoccidial activity. Monensin is widely used to treat such infections and as a feed additive to promote the growth of livestock.

Chemical Properties

Crystallin Solid

Uses

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.

Uses

Poliether antibiotic. Coccidiostat

Uses

Monensin (2) C36H62O11, a carboxylic acid which is used as its water-soluble sodium salt (Coban, Rumensin). Monensin is also used to treat histomoniasis. The polyether ionophoric antibiotics are capable of complexing and interfacing with specific alkali metal cations to render them lipid-soluble and diffusible across parasite mitochondrial membranes. Related useful polyether antibiotics are narasin and lasalocid (3, Lasalocid A, C34H54O8,).

Definition

ChEBI: Monensin A is a spiroketal, monensin A is the major component of monensin, a mixture of antibiotic substances produced by Streptomyces cinnamonensis. An antiprotozoal, it is used as the sodium salt as a feed additive for the prevention of coccidiosis in poultry and as a growth promoter in cattle. It has a role as a coccidiostat, an antifungal agent and an ionophore. It is a monocarboxylic acid, a cyclic hemiketal, a spiroketal and a polyether antibiotic.

brand name

Coban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).

Safety Profile

Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

Monensin Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Monensin manufacturers

Henan Suikang Pharmaceutical Co.,Ltd.

Product: Monensin 17090-79-8
Price: US $0.00/kg
Min. Order: 25kg
Purity: 99.0%
Supply Ability: 10tons
Release date: 2024-04-29

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Monensin 17090-79-8
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000kg
Release date: 2024-04-07

Henan Fengda Chemical Co., Ltd

Product: Monensin 17090-79-8
Price: US $34.00-1.20/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2024-03-22

17090-79-8, MonensinRelated Search:

Methylparaben Bensulfuron methyl Ivermectin Nystatin CHLOROPHOSPHONAZO III METSULFURON METHYL Methyl salicylate Thiophanate-methyl Kresoxim-methyl Abamectin Methyl Methyl bromide MONENSIN SODIUM SALT HYDRATE,monensin,monosodiumsal Parathion-methyl 16-Deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)monensin,Monensin, 16-deethyl-3-O-demethyl-16-methyl-3-O-(1-oxopropyl)- monensin B Monensin 26-[N-(2-phenylethyl)carbamate] MONENSIN DECYL ESTER

2-(5-ethyltetrahydro-5-(tetrahydro-3-6-dioxaspiro(4.5)decane-7-butyricacid

a3823a

elancoban

gamma,2,8-tetramethyl--furyl)-2-furyl)-9-hydroxy-beta-methoxy-alph

monelan

Monensine sodium

4-[2-[2-Ethyl-5-(6-hydroxy-6-hydroxymethyl-3,5-dimethyltetrahydropyran-2-yl)-3-methyloctahydro-[2,2]bifuranyl-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl]-3-methoxy-2-methylpentanoic acid

Monensin A

4-[2-(5-ethyl-5-{5-[6-hydroxy-6-(hydroxyMethyl)-3,5-diMethyloxan-2-yl]-3-Methyloxolan-2-yl}oxolan-2-yl)-9-hydroxy-2,8-diMethyl-1,6-dioxaspiro[4.5]decan-7-yl]-3-Methoxy-2-Methylpentanoic acid

Monensin 20%

Monensic acid, Lilly 67314, A 3223A.

Monensin premix

MONENSIN NA

MONENSIN SODIUM

MONENSIN A SODIUM SALT

MONENSIN

monensicacid

4-[3-[5-ETHYL-5-[5-[6-HYDROXY-6-(HYDROXYMETHYL)-3,5-DIMETHYL-TETRAHYDROPYRAN-2-YL]-3-METHYL-TETRAHYDROFURAN-2-YL]-TETRAHYDROFURAN-2-YL]-9-HYDROXY-3,8-DIMETHYL-4,6-DIOXASPIRO[4.5]DEC-7-YL]-3-METHOXY-2-METHYL-PENTANOATE

2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy-beta-methoxy-alpha,gamma,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric acid

Romensin

2-[5-Ethyltetrahydro-5-[tetrahydro-3-methyl-5-[tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-2-furyl]-2-furyl]-9-hydroxy--methoxy-a,,2,8-tetramethyl-1,6-dioxaspiro[4.5]decane-7-butyric Acid

MONENSIN(PURE)

MONENSINSODIUMSALT(30%)

Monensin：Monesin Sodium

Monensin USP/EP/BP

17090-79-8 Monensin

17090-79-8

2411-54-0

C36H61O11Na

C36H62O11

C37H63NaO10

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