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Saikosaponin a

Product Name
Saikosaponin a
CAS No.
20736-09-8
Chemical Name
Saikosaponin a
Synonyms
SAIKOSAPONIN A;Saikosaponian A;SAILKOSAPONIN A;SAILKOSAPONINS A;Thesaikosaponin A;Saikosaponin A-RM;SAIKOSAPONIN A(RG);Saikosaponin A CRS;SABINYL ACETATE(RG);Saikosaponin a std.
CBNumber
CB0735476
Molecular Formula
C42H68O13
Formula Weight
780.98
MOL File
20736-09-8.mol
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Saikosaponin a Property

Melting point:
225~232℃ (dec.)
Boiling point:
893.7±65.0 °C(Predicted)
Density 
1.163~1.168 g/ml
refractive index 
1.571~1.574 (20/D)
storage temp. 
Hygroscopic, Refrigerator, under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly, Sonicated), Pyridine (Slightly)
pka
12.83±0.70(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
InChIKey
KYWSCMDFVARMPN-FMIBPMOUSA-N
CAS DataBase Reference
20736-09-8
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Safety

Safety Statements 
24/25
HS Code 
29389090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
PHL89526
Product name
Saikosaponin A
Purity
phyproof? Reference Substance
Packaging
10MG
Price
$403
Updated
2025/07/31
TCI Chemical
Product number
A3408
Product name
Saikosaponin A
Packaging
10MG
Price
$77
Updated
2025/07/31
TCI Chemical
Product number
A3408
Product name
Saikosaponin A
Packaging
50MG
Price
$229
Updated
2025/07/31
Cayman Chemical
Product number
25026
Product name
Saikosaponin A
Purity
≥98%
Packaging
1mg
Price
$37
Updated
2024/03/01
Cayman Chemical
Product number
25026
Product name
Saikosaponin A
Purity
≥98%
Packaging
5mg
Price
$116
Updated
2024/03/01
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Saikosaponin a Chemical Properties,Usage,Production

Chemical Properties

Pale yellow crystals, easily soluble in water and dilute alcohol, difficult to dissolve in benzene, ether and chloroform, derived from the aerial parts of Bupleurum chinense.

Uses

Saikosaponin A was shown to exhibit anti-inflammatory activities by suppressing activation of NF-kB signaling pathway.

Definition

ChEBI: Saikosaponin A is a saikosaponin.

in vivo

Saikosaponin A (1-10 mg/kg, i.p, 7 d) attenuates the morphological changes in the small intestine induced by 5-FU[2].
Saikosaponin-A (1-10 mg/kg, i.p, 7 d) enhances the decrease of antioxidant enzymes in intestinal tissue caused by 5-FU[2].

Animal Model:5-FU (HY-90006)-induced mucositis in BALB/c mice modle[2]
Dosage:1, 5, 10?mg/kg/day, 7 d
Administration:injected intraperitoneally (i.p)
Result:Reduced villus blunting, crypt cells apoptosis, and inflammatory cell infiltration.
Decreased concentration of GSH, GST, Catalase, and SOD in intestinal tissue.

Saikosaponin a Preparation Products And Raw materials

Raw materials

Preparation Products

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Saikosaponin a Suppliers

cfm Oskar Tropitzsch
Tel
--
Fax
--
Country
Germany
ProdList
1136
Advantage
62
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from Saikosaponin a manufacturers

Shaanxi Haibo Biotechnology Co., Ltd
Product
Saikosaponin A 20736-09-8
Price
US $0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
2000ton
Release date
2023-08-21
Shanghai Standard Technology Co., Ltd.
Product
Saikosaponin A 20736-09-8
Price
US $0.00/mg
Min. Order
5mg
Purity
≥98%(HPLC)
Supply Ability
10 g
Release date
2019-09-29
Shanghai Standard Technology Co., Ltd.
Product
Saikosaponin A 20736-09-8
Price
US $0.00/mg
Min. Order
5mg
Purity
Analytical Standard
Supply Ability
10 g
Release date
2019-09-29

20736-09-8, Saikosaponin aRelated Search:


  • SAIKOSAPONIN A(RG)
  • Thesaikosaponin A
  • SAIKOSAPONIN A
  • dihydroxyolean-11-en-3-yl6-deoxy-3-O-β-D-
  • β-D-fucoside, (3β,4α,16β)-13,28-epoxy-16,23-
  • [(3β,4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside
  • [(4R)-13,28-Epoxy-16β,23-dihydroxyolean-11-en-3β-yl]3-O-(β-D-glucopyranosyl)-6-deoxy-β-D-galactopyranoside
  • SABINYL ACETATE(RG)
  • (3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl-6-deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
  • Saikosaponian A
  • SAILKOSAPONINS A
  • Saikosaponin a std.
  • SAILKOSAPONIN A
  • Saikosaponin A, 98%, from Bupleurum chinense DC.
  • Saikosaponin A 20736-09-8
  • Bupleurum saikosaponin A
  • Saikosaponin A CRS
  • (3beta,4alpha,16beta)-13,28-Epoxy-16,23-dihydroxyolean-11-en-3-yl 6-Deoxy-3-O-beta-D-glucopyranosyl-beta-D-galactopyranoside
  • β-D-Galactopyranoside
  • (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-3,5-dihydroxy-2-(((3S,4R,4aR,6aR,6bS,8S,8aS,12aR,12bS,14aR,14bS)-8-hydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-1,2,3,4,4a,5,6,6a,6b,7,8,9,10,11,12,12a,14a,14b-octadecahydro-12b,8a-(epoxymethano)picen-3-yl)oxy)-6-methyltetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • β-D-Galactopyranoside, (3β,4α,16β)-13,28-epoxy-16,23-dihydroxyolean-11-en-3-yl 6-deoxy-3-O-β-D-glucopyranosyl-
  • (2S,3R,4S,5S,6R)-2-(((2R,3R,4S,5S,6R)-3,5-Dihydroxy-2-(((3S,4R,4aR,6aR,6bS,8S,8aS,12aR,12bS,14aR,14bS)-8-hydroxy-4-(hydroxymethyl)-4,6a,6b,11,11,14b-hexamethyl-2,3,4,4a,5,6,6a,6b,7,8,10,11,12,12a,14a,14b-hexadecahydro-1H,9H-12b,8a-(epoxymethano)picen-3-yl)oxy)-6-methyltetrahydro-2H-pyran-4-yl)oxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
  • Saikosaponin A-RM
  • Saikosaponin A, 10 mM in DMSO
  • 20736-09-8
  • C42H68O13
  • chemical reagent
  • pharmaceutical intermediate
  • phytochemical
  • reference standards from Chinese medicinal herbs (TCM).
  • standardized herbal extract
  • Inhibitors
  • Saponins