ChemicalBook > CAS DataBase List > Indole-5-carboxylic acid

Indole-5-carboxylic acid

Product Name
Indole-5-carboxylic acid
CAS No.
1670-81-1
Chemical Name
Indole-5-carboxylic acid
Synonyms
1H-INDOLE-5-CARBOXYLIC ACID;JACS-1670-81-1;5-CARBOXYINDOLE;5-Carboxy-1H-indole;RARECHEM AL BO 0206;TIMTEC-BB SBB003951;Indolecarboxylicacid,5-;5-INDOLECARBOXYLIC ACID;INDOLE-5-CARBOXYLIC AICD;INDOLE-5-CARBOXYLIC ACID
CBNumber
CB0736428
Molecular Formula
C9H7NO2
Formula Weight
161.16
MOL File
1670-81-1.mol
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Indole-5-carboxylic acid Property

Melting point:
211-213 °C (lit.)
Boiling point:
287.44°C (rough estimate)
Density 
1.2480 (rough estimate)
refractive index 
1.5050 (estimate)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in ethanol (50 mg/ml), dimethyl sulfoxide and methanol.
form 
Powder
pka
4.40±0.30(Predicted)
color 
Light beige to yellow
BRN 
124391
InChIKey
IENZCGNHSIMFJE-UHFFFAOYSA-N
CAS DataBase Reference
1670-81-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn,Xi
Risk Statements 
36/37/38-21/22
Safety Statements 
22-24/25-36/37/39-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TCI Chemical
Product number
I0029
Product name
Indole-5-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
1g
Price
$42
Updated
2024/03/01
TCI Chemical
Product number
I0029
Product name
Indole-5-carboxylic Acid
Purity
>98.0%(GC)(T)
Packaging
5g
Price
$81
Updated
2024/03/01
Alfa Aesar
Product number
A18627
Product name
Indole-5-carboxylic acid, 98%
Packaging
1g
Price
$40.65
Updated
2024/03/01
Alfa Aesar
Product number
A18627
Product name
Indole-5-carboxylic acid, 98%
Packaging
5g
Price
$133
Updated
2024/03/01
Alfa Aesar
Product number
A18627
Product name
Indole-5-carboxylic acid, 98%
Packaging
25g
Price
$493.65
Updated
2024/03/01
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Indole-5-carboxylic acid Chemical Properties,Usage,Production

Chemical Properties

light beige to yellow powder

Uses

Reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators 1 Reactant for preparation of indolyl-quinolines via metal- and solvent-free autoxidative coupling reaction 2 Reactant for preparation of anthranilic acids using bromamine-B oxidant and palladium chloride catalyst 3 Reactant for synthesis of indirubin derivatives 4 Reactant for preparation of amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway 5 Reactant for preparation of piperazine-bisamide analogs as human growth hormone secretagogue receptor antagonists for treatment of obesity.

Uses

Indole-5-carboxylic acid is the suitable reagent used to study the intermolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films. Also used as reactant for preparation of tryptophan dioxygenase inhibitors pyridyl-ethenyl-indoles, as potential anticancer immunomodulators, synthesis of indirubin derivatives and amide conjugates with ketoprofen, as inhibitors of Gli1-mediated transcription in Hedgehog pathway.

Uses

Indole-5-carboxylic acid is the suitable reagent used to study the intramolecular excited state proton transfer in indole-2-carboxylic acid and indole-5-carboxylic acid in various solvents in acidic, basic, and neutral media by steady state and time resolved fluorescence spectroscopy. It may be used in the electrochemical synthesis of poly(indole-5-carboxylic acid) (PICA) films.

Definition

ChEBI: Indole-5-carboxylic acid is an indolecarboxylic acid in which the carboxy group is the only substituent and is located at position 5. It has a role as a plant metabolite.

General Description

Indole-5-carboxylic acid is an indole derivative. On electropolymerization, it affords electroactive polymer film of poly(indole-5-carboxylic-acid). Different concentrations of indole-5-carboxylic acid in sulfuric acid solution has been investigated for the preventive action against mild steel corrosion. On electropolymerization it affords a trimeric product. Characterization studies of the trimeric product by 1H NMR and various one- and two-dimensional NMR techniques have been reported.

Indole-5-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Indole-5-carboxylic acid manufacturers

Zhuozhou Wenxi import and Export Co., Ltd
Product
Indole-5-carboxylic acid 1670-81-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-08-11
Chemwill Asia Co.,Ltd.
Product
Indole-5-carboxylic acid in stock Factory 1670-81-1
Price
US $1.00/KG
Min. Order
1KG
Purity
TOP 3 Factory in China
Supply Ability
Top 3 production capacity Factory
Release date
2019-04-03
Nanjing jinheyou Trading Co., Ltd.
Product
Indole-5-carboxylic acid 1670-81-1
Price
US $0.00/g
Min. Order
1g
Purity
95%min
Supply Ability
20kg/month
Release date
2019-12-20

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