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DI-TERT-BUTYL IMINODIACETATE

Product Name
DI-TERT-BUTYL IMINODIACETATE
CAS No.
85916-13-8
Chemical Name
DI-TERT-BUTYL IMINODIACETATE
Synonyms
NH-bis(C1-Boc);N-BIS(T-BUTYLACETATE)AMINE;DI-TERT-BUTYL IMINODIACETATE;DL-tert-Butyl Iminodiacetate;Di-tert-butylIminodiacetate>Di-tert-butyl iminodiacetate 98%;di-tert-butyl 2,2'-iminodiacetate;Di-tert-butyl Iminodiacetate;Di-tert-butyl 2,2'-iminobis[acetate];Di-tert-butyl iminodiacetate≥ 98%(GC)
CBNumber
CB0738891
Molecular Formula
C12H23NO4
Formula Weight
245.32
MOL File
85916-13-8.mol
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DI-TERT-BUTYL IMINODIACETATE Property

Melting point:
38-42 °C(lit.)
Boiling point:
298.0±25.0 °C(Predicted)
Density 
1.011±0.06 g/cm3(Predicted)
Flash point:
>230 °F
storage temp. 
2-8°C(protect from light)
solubility 
soluble in Methanol
form 
powder to lump to clear liquid
pka
4.52±0.20(Predicted)
color 
White or Colorless to Almost white or Almost colorless
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36/37/39
WGK Germany 
3
HS Code 
29224999
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
511323
Product name
Di-tert-butyl iminodiacetate
Purity
98%
Packaging
1g
Price
$59.47
Updated
2025/07/31
Sigma-Aldrich
Product number
511323
Product name
Di-tert-butyl iminodiacetate
Purity
98%
Packaging
5g
Price
$225.28
Updated
2025/07/31
TCI Chemical
Product number
D4109
Product name
Di-tert-butyl Iminodiacetate
Purity
>97.0%(GC)
Packaging
1g
Price
$57
Updated
2025/07/31
TCI Chemical
Product number
D4109
Product name
Di-tert-butyl Iminodiacetate
Purity
>97.0%(GC)
Packaging
5g
Price
$186
Updated
2025/07/31
TRC
Product number
D492920
Product name
DL-tert-ButylIminodiacetate
Packaging
100mg
Price
$60
Updated
2021/12/16
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DI-TERT-BUTYL IMINODIACETATE Chemical Properties,Usage,Production

Chemical Properties

White to tan solid

Uses

Di-tert-butyl iminodiacetate may be used as a reagent in the synthesis of:

  • multi-carboxylic acid-containing carbocyanine dyes
  • monosubstituted difunctionalized polyhedral oligomeric silsesquioxanes (POSS) monomers
  • multigenerational fluorinated dendrimers
  • 2,6-dipyrazol-1-ylpyridine derivatives
It may also be used for the preparation of di-tert-butyl N-(4-allyloxy-4-oxobutanoyl)iminodiacetate.

General Description

Di-tert-butyl iminodiacetate is a secondary amine.

Synthesis

107-59-5

85916-13-8

The general procedure for the synthesis of di-tert-butyl iminodiacetate from tert-butyl chloroacetate is as follows: in a 250 mL three-necked flask equipped with a thermometer, condenser tube and mechanical stirring device, 120 mL of methanol was added. Under continuous stirring, 120.0 g of tert-butyl chloroacetate (0.8 mol) was heated to 65 °C and 5.1 g of ammonia (0.3 mol) was slowly passed through. The reaction was carried out for 2 hours and then continued to hold the reaction for 5 hours. After the reaction mixture was cooled to room temperature, it was filtered to remove the resulting white solid ammonium chloride. The filtrate was concentrated by rotary evaporation to recover about 110 mL of methanol. The concentrated residue was cooled to 0 °C to induce precipitation of the product. The precipitate was collected by filtration to give 23.3 g of di-tert-butyl iminodiacetate with a melting point of 41 °C.

IC 50

Non-cleavable Linker

References

[1] Patent: CN108191686, 2018, A. Location in patent: Paragraph 0040-0073

DI-TERT-BUTYL IMINODIACETATE Preparation Products And Raw materials

Raw materials

Preparation Products

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DI-TERT-BUTYL IMINODIACETATE Suppliers

J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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TCI (Shanghai) Development Co., Ltd.
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021-67121386
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021-67121385
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Sales-CN@TCIchemicals.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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Suzhou Highfine Biotech Co., Ltd
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0512-69209928 18796809688
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0512-68417696
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zhouyingxiang@highfine.com
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China
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Sichuan Guanghan Bio-Tech Co., Ltd
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+86-28-86127071
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+86-28-86127072
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info@sino-produce.com
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China
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Shandong Xiya Chemical Co., Ltd
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4009903999 13355009207
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0539-6365991
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3007715519@qq.com
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Syntechem Co.,Ltd
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Tianjin heowns Biochemical Technology Co., Ltd.
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400 638 7771
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China
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Sinopharm Chemical Reagent Co,Ltd.
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86-21-63210123
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86-21-63290778 86-21-63218885
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sj_scrc@sinopharm.com
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China
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Lavem Chine Pharm Company
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028-62070218 18190869852
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86-28-8527-5264
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sales@lavemc.com
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China
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View Lastest Price from DI-TERT-BUTYL IMINODIACETATE manufacturers

Henan Fengda Chemical Co., Ltd
Product
DI-TERT-BUTYL IMINODIACETATE 85916-13-8
Price
US $34.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-04-08
Career Henan Chemical Co
Product
DI-TERT-BUTYL IMINODIACETATE 85916-13-8
Price
US $1.00/KG
Min. Order
1KG
Purity
≥98%
Supply Ability
200KG
Release date
2019-08-30

85916-13-8, DI-TERT-BUTYL IMINODIACETATERelated Search:


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