N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE

Product Name: N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE
CAS No.: 23008-56-2
Chemical Name: N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE
Synonyms: N-(4-chlorophenyl)-2-nitroaniline;C.I.10336;Disperse Yellow 22;TIMTEC-BB SBB003165;C.I.Disperse Yellow 22;SRA Fast Golden Yellow XII;2-NITRO-4'-CHLORDIPHENYLAMIN;4'-CHLORO-2-NITRODIPHENYLAMINE;4-Chloro-2'-nitrodiphenylamine;2-NITRO-4'-CHLORO DIPHENYLAMINE
CBNumber: CB0748894
Molecular Formula: C12H9ClN2O2
Formula Weight: 248.67
MOL File: 23008-56-2.mol

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N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE Property

Melting point:: 145-148 °C(lit.)
Boiling point:: 377.2±27.0 °C(Predicted)
Density: 1.387±0.06 g/cm3(Predicted)
storage temp.: 2-8°C(protect from light)
pka: -3.90±0.40(Predicted)
Appearance: Brown to dark brown Solid
InChI: InChI=1S/C12H9ClN2O2/c13-9-5-7-10(8-6-9)14-11-3-1-2-4-12(11)15(16)17/h1-8,14H
InChIKey: RCLKXSIRDRWUGX-UHFFFAOYSA-N
SMILES: C1(NC2=CC=C(Cl)C=C2)=CC=CC=C1[N+]([O-])=O
CAS DataBase Reference: 23008-56-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-36
WGK Germany: 3
Hazard Note: Irritant
HS Code: 2921490090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: N495948
Product name: 2-Nitro-4''-chlorodiphenylamine
Packaging: 1g
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 240349
Product name: N-(4-Chlorophenyl)-2-nitroaniline
Purity: 98%
Packaging: 1g
Price: $20
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4655-5-10
Product name: 4'-Chloro-2-nitrodiphenylamine
Purity: 98%
Packaging: 1g
Price: $24
Updated: 2021/12/16

AK Scientific

Product number: Z2392
Product name: 2-(4-Chlorophenylamino)nitrobenzene
Packaging: 1g
Price: $77
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4655-5-10
Product name: 4'-Chloro-2-nitrodiphenylamine
Purity: 98%
Packaging: 5G
Price: $87
Updated: 2021/12/16

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N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE Chemical Properties,Usage,Production

Uses

2-?Nitro-?4''-?chlorodiphenylamine is a reagent used in the synthesis of novel 4-phenoxyquinoline derivatives as c-Met kinase inhibitors. Intermediate for Clofazimine.

Preparation

4-Chlorobenzenamine and 1-Chloro-2-nitrobenzene?condensation

Synthesis

106-47-8

1493-27-2

23008-56-2

GENERAL METHOD: Suspend NaH (75 mmol) in DMF (60 mL) at 0°C and slowly add 4-chloroaniline (50 mmol). After stirring for 30 min at 0°C, a solution of 1-fluoro-2-nitrobenzene (60 mmol) in DMF (30 mL) was added dropwise. The reaction mixture was gradually warmed to room temperature and stirred continuously for 16 hours. Upon completion of the reaction, the mixture was carefully poured into a stirred saturated NH4Cl solution (500 mL) and the precipitate was collected by filtration. The filter cake was washed with water and purified by recrystallization from methanol to give the target product N-(4-chlorophenyl)-2-nitroaniline (15h). The product was an orange solid with a yield of 72.3% and a melting point of 135.1-137.0 °C. 1H NMR (400 MHz, DMSO-d6) δ 9.31 (s, 1H), 8.12 (d, J = 8.0 Hz, 1H), 7.53 (t, J = 7.6 Hz, 1H), 7.44 (d, J = 8.8 Hz, 2H), 7.34 (d, J = 8.8 Hz, 2H), 7.22 (d, J = 8.4 Hz, 1H), 6.93 (t, J = 7.6 Hz, 1H).MS (ESI) m/z (%): 247.2 [M-H]-.

Properties and Applications

Brilliant yellow

StandardVinegar fiber	Ironing Fastness		Light Fastness	Persperation Fastness		Washing Fastness
StandardVinegar fiber	Fading	Stain	Light Fastness	Fading	Stain	Fading	Stain
ISO			7	4	4	3	2

References

[1] Patent: CN106916069, 2017, A. Location in patent: Paragraph 0016; 0017; 0018; 0019; 0020; 0021; 0022-0024
[2] Organic Process Research and Development, 2016, vol. 20, # 2, p. 452 - 464
[3] Molecules, 2012, vol. 17, # 4, p. 4545 - 4559
[4] Synlett, 2003, # 4, p. 564 - 566
[5] Bioorganic and Medicinal Chemistry, 2017, vol. 25, # 16, p. 4475 - 4486

N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE Suppliers

China 88 France 1 India 4 Switzerland 1 United Kingdom 4 United States 11 Global 109

Hangzhou Copiore Chemical Co., Ltd.

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View Lastest Price from N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE manufacturers

Honest Joy Holdings Limited

Product: N-(4-chlorophenyl)-2-nitroaniline 23008-56-2
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.1%
Supply Ability: 100 tons
Release date: 2022-01-14

Zhuozhou Wenxi import and Export Co., Ltd

Product: N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE 23008-56-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

Career Henan Chemical Co

Product: N-(4-CHLOROPHENYL)-2-NITROBENZENAMINEE 23008-56-2
Price: US $1.00/KG
Min. Order: 1KG
Purity: 97%-98%
Supply Ability: 200KG
Release date: 2019-09-03

23008-56-2, N-(4-CHLOROPHENYL)-2-NITROBENZENAMINERelated Search:

N-(4-fluoro-2-Methoxy-5-nitrophenyl)-4-(1-Methylindol-3-yl)pyriMidin-2-aMine N-(5-Chloro-2-methylphenyl)-7- nitrobenzo[c][1,2,5]oxadiazol-4-amine Disperse Yellow 223 C.I. Disperse Yellow 218 Disperse Yellow 224 Disperse Yellow 220 Disperse Yellow 229 Disperse Yellow 221 Disperse yellow 227 Disperse Yellow 219 Disperse Yellow 226 2,4-DINITROBENZENESULFONYL CHLORIDE 2-Nitrodiphenylamine 5-CHLORO-2-NITRODIPHENYLAMINE N1-(4-Chlorophenyl)benzene-1,2-diamine N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE

2-NITRO-4'-CHLORO DIPHENYLAMINE

2-NITRO-4'-CHLORDIPHENYLAMIN

N-(4-CHLOROPHENYL)-2-NITROBENZENAMINEE

4'-CHLORO-2-NITRODIPHENYLAMINE

4-Chloro-N-(2-nitrophenyl)aniline

C.I.10336

C.I.Disperse Yellow 22

SRA Fast Golden Yellow XII

(4-chlorophenyl)-(2-nitrophenyl)amine

TIMTEC-BB SBB003165

N-(4-CHLOROPHENYL)-2-NITROBENZENAMINE

N-(4-chlorophenyl)-2-nitroaniline

4'-Chloro-2-nitrodiphenylamine98%

2-(4-Chlorophenylamino)-1-nitrobenzene

N-(4-Chloropheny)-2-NitrobenzenamineI

Benzenamine, N-(4-chlorophenyl)-2-nitro-

C.I.Disperse Yellow 22:C.I.1033

Disperse Yellow 22

4-Chloro-2'-nitrodiphenylamine

2-Nitro-4′-chlorodiphenylamine, CAS 23008-56-2

N-(4-chlorophenyl)-2-nitroaniline 95%

23008-56-2

ClC6H4NHC6H4NO2