2-FLUORO-4-PYRIDINEMETHANOL
- Product Name
- 2-FLUORO-4-PYRIDINEMETHANOL
- CAS No.
- 131747-60-9
- Chemical Name
- 2-FLUORO-4-PYRIDINEMETHANOL
- Synonyms
- (2-Fluoropyridin-4-yl)methanol;2-FLUORO-4-PYRIDINEMETHANOL;(2-fluoro-4-pyridyl)methanol;4-PyridineMethanol, 2-fluoro-;2-Fluoro-4-hydroxymethylpyridine;2-Fluoro-4-pyridinemethanol ,96%;4-Pyridinemethanol,2-fluoro-(9CI);(2-fluoro-4-pyridyl)methanol - [F82319]
- CBNumber
- CB0752138
- Molecular Formula
- C6H6FNO
- Formula Weight
- 127.12
- MOL File
- 131747-60-9.mol
2-FLUORO-4-PYRIDINEMETHANOL Property
- Melting point:
- 59.3-60.4 °C
- Boiling point:
- 247.4±25.0 °C(Predicted)
- Density
- 1.262±0.06 g/cm3(Predicted)
- storage temp.
- Storage temp. 2-8°C
- form
- solid
- pka
- 13.05±0.10(Predicted)
- Appearance
- White to off-white Solid
- InChIKey
- IAFXOPAZVVMMLE-UHFFFAOYSA-N
Safety
- Hazard Codes
- F
- Risk Statements
- 10-36/37/38-20/21/22
- Safety Statements
- 16-26-36
- HazardClass
- IRRITANT
- HS Code
- 29333990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
N-Bromosuccinimide Price
- Product number
- MNO000064
- Product name
- (2-Fluoropyridin-4-yl)methanol
- Purity
- Aldrich
- Packaging
- 1g
- Price
- $185
- Updated
- 2025/07/31
- Product number
- B435035
- Product name
- (2-Fluoropyridin-4-yl)methanol
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 064055
- Product name
- (2-Fluoropyridin-4-yl)methanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $69
- Updated
- 2021/12/16
- Product number
- 4H01-3-32
- Product name
- (2-Fluoropyridin-4-yl)methanol
- Purity
- 97%
- Packaging
- 250mg
- Price
- $113
- Updated
- 2021/12/16
- Product number
- PC905392
- Product name
- (2-Fluoropyridin-4-yl)methanol
- Purity
- 98%
- Packaging
- 1g
- Price
- $232
- Updated
- 2021/12/16
2-FLUORO-4-PYRIDINEMETHANOL Chemical Properties,Usage,Production
Chemical Properties
Light yellow low melting solid
Synthesis
1006300-11-3
131747-60-9
General procedure for the synthesis of 2-fluoro-4-pyridinemethanol (37) from 2-fluoro-4-pyridinecarboxylic acid phenylmethyl ester (36) (4.536 g, 19.62 mmol): to a stirred solution of 2-fluoro-4-pyridinecarboxylic acid phenylmethyl ester (36) in anhydrous methanol (40 mL) was added sodium methanolate (1.06 g, 19.62 mmol) under ice bath cooling. After stirring for 30 min, an excess of ammonium chloride was added to the reaction mixture. Subsequently, the mixture was concentrated by evaporation under vacuum and the residue was purified by silica gel column chromatography (eluent: ether/hexane, 1:1, v/v) to afford 2.34 g (94% yield) of 2-fluoro-4-pyridinylmethanol (37) as a white solid with a melting point of 70-71°C. 1H NMR (200 MHz, CDCl3) δ: 2.40 (1H, t, J = 4.0 Hz), 4.78 (2H, d, J = 4.0 Hz), 6.97 (1H, s), 7.15 (1H, m), 8.15 (1H, d, J = 5.0 Hz); Mass Spectrum (EI): m/z 127 (M+).
References
[1] Patent: US2008/70920, 2008, A1. Location in patent: Page/Page column 37-38
[2] Bioorganic and Medicinal Chemistry Letters, 2010, vol. 20, # 5, p. 1585 - 1588
2-FLUORO-4-PYRIDINEMETHANOL Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 2-FLUORO-4-PYRIDINEMETHANOL manufacturers
- Product
- 2-FLUORO-4-PYRIDINEMETHANOL 131747-60-9
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2020-01-02