2,3-Difluoropyridine-4-carboxylic acid

Product Name: 2,3-Difluoropyridine-4-carboxylic acid
CAS No.: 851386-31-7
Chemical Name: 2,3-Difluoropyridine-4-carboxylic acid
Synonyms: 2,3-Difluoroisonicotinic acid;2,3-Fifluoroisonicotinic acid;2,3-Difluoro-4-carboxypyridine;2,3-Difluoroisonicotinic acid 97%;2,3-difluoro-4-pyridinecarboxylic acid;2,3-Difluoropyridine-4-carboxylic acid;2,3-difluoroisonicotinic acid, 98%min;4-Pyridinecarboxylic acid, 2,3-difluoro-;2,3-Difluoropyridine-4-carboxylicacid,97%;2,3-Difluoropyridine-4-carboxylic acid ISO 9001：2015 REACH
CBNumber: CB11471031
Molecular Formula: C6H3F2NO2
Formula Weight: 159.09
MOL File: 851386-31-7.mol

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2,3-Difluoropyridine-4-carboxylic acid Property

Melting point:: 159-160 °C
Boiling point:: 377.4±37.0 °C(Predicted)
Density: 1.535
storage temp.: 2-8°C
solubility: soluble in Methanol
form: powder to crystal
pka: 2.10±0.10(Predicted)
color: White to Orange to Green
InChI: 1S/C6H3F2NO2/c7-4-3(6(10)11)1-2-9-5(4)8/h1-2H,(H,10,11)
InChIKey: FFGHMEKFPCGYEG-UHFFFAOYSA-N
SMILES: OC(=O)c1ccnc(F)c1F
CAS DataBase Reference: 851386-31-7

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 2933399990
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 759392
Product name: 2,3-Difluoropyridine-4-carboxylic acid
Purity: 97%
Packaging: 1g
Price: $68.9
Updated: 2023/06/20

TCI Chemical

Product number: D5131
Product name: 2,3-Difluoroisonicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $24
Updated: 2026/03/19

TCI Chemical

Product number: D5131
Product name: 2,3-Difluoroisonicotinic Acid
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $105
Updated: 2026/03/19

TRC

Product number: D445393
Product name: 2,3-Difluoropyridine-4-carboxylic acid
Packaging: 500mg
Price: $75
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD63571
Product name: 2,3-Difluoroisonicotinic acid
Packaging: 5G
Price: $80
Updated: 2021/12/16

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2,3-Difluoropyridine-4-carboxylic acid Chemical Properties,Usage,Production

Uses

2,3-Difluoropyridine-4-carboxylic acid is particularly important as starting materials for agrochemicals and pharmaceuticals.

Synthesis

To a solution of n-BuLi (26.1 mL, 52.09 mmol) in THF (70 mL, Na distilled) was added N,N-diisopropylamine (7.30 mL, 52.09 mmol) and 2,3-difluoropyridine (5.00 g, 43.41 mmol) successively at -78 C. The resulting mixture was stirred at -78C for 1 hour and then poured over crushed dry ice (excess). The reaction was allowed to warm up to room temperature for 1 h and after evaporation of the excess dry ice and THF, the residue was added to water (100 mL) and washed with EtOAc (2 x 50 mL). The aqueous layer was then acidified to pH 1 and extracted with EtOAc (2 x 100 mL). The combined organic extracts were dried and evaporated to give the product 2,3-difluoropyridine-4-carboxylic acid. Yield = 2.39 g, 35%.

2,3-Difluoropyridine-4-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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2,3-Difluoropyridine-4-carboxylic acid Suppliers

Americas 1 Belgium 1 China 131 Europe 1 France 1 Germany 8 India 5 Japan 1 Switzerland 1 Ukraine 1 United Kingdom 6 United States 38 Global 195

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View Lastest Price from 2,3-Difluoropyridine-4-carboxylic acid manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 2,3-Difluoropyridine-4-carboxylic acid 851386-31-7
Price: US $1.10/g
Min. Order: 1g
Purity: 99.0% min
Supply Ability: 100 tons min
Release date: 2021-05-26

Career Henan Chemical Co

Product: 2,3-Difluoropyridine-4-carboxylic acid 851386-31-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 1ton
Release date: 2019-07-11

Career Henan Chemical Co

Product: 2,3-Difluoropyridine-4-carboxylic acid 851386-31-7
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: Customized
Release date: 2018-12-14

851386-31-7, 2,3-Difluoropyridine-4-carboxylic acidRelated Search:

2-Picolinic acid 3-(Trifluoromethyl)benzoic acid Chromium picolinate Ethyl 2-(Chlorosulfonyl)acetate Zinc picolinate 2,3-Difluoropyridine Folic acid Ascoric Acid CARBOXYLIC ACID 2,3,5-TRIFLUOROPYRIDINE-4-CARBOXYLIC ACID, 97 2,3,6-TRIFLUOROISONICOTINIC ACID 2-Amino-3,5,6-trifluoro-4-pyridinecarboxylicacidethylester 2,3,5,6-TETRAFLUOROPYRIDINE-4-CARBOXYLIC ACID phosphoric acid 2,3-Difluoropyridine-4-carboxylic acid

2,3-Difluoropyridine-4-carboxylic acid

4-Pyridinecarboxylic acid, 2,3-difluoro-

2,3-Difluoropyridine-4-carboxylic acid, 4-Carboxy-2,3-difluoropyridine

2,3-Difluoro-4-carboxypyridine

2,3-Fifluoroisonicotinic acid

2,3-difluoro-4-pyridinecarboxylic acid

2,3-Difluoroisonicotinic acid

2,3-Difluoroisonicotinic acid 97%

2,3-Difluoropyridine-4-carboxylicacid,97%

2,3-Difluoropyridine-4-carboxylic acid ISO 9001：2015 REACH

2, 3-difluoroisonicotinic acid /2, 3-difluoropyridine-4-carboxylic acid

2,3-difluoroisonicotinic acid, 98%min

851386-31-7

Fluorine series