PPADS TETRASODIUM SALT

Product Name: PPADS TETRASODIUM SALT
CAS No.: 192575-19-2
Chemical Name: PPADS TETRASODIUM SALT
Synonyms: PPADS;PPADS Tetrasodium;4'-disulfonic acid;PPADS (sodium salt);PPADS TETRASODIUM SALT;PPADS tetrasodium salt hydrate;PPADS tetrasodium salt, anhydrous;Pyridoxalphosphate-6-azophenyl-2';pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni;PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA
CBNumber: CB0758079
Molecular Formula: C14H15N3NaO12PS2
Formula Weight: 535.37
MOL File: 192575-19-2.mol

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PPADS TETRASODIUM SALT Property

storage temp.: −20°C
solubility: H₂O: >10 mg/mL
form: solid
color: red to orange
Water Solubility: Soluble to 100 mM in water
Stability:: Unstable in Aqueous Solution

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Safety

Safety Statements: 22-24/25
WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: P178
Product name: Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity: solid, ≥98% (HPLC)
Packaging: 10mg
Price: $100
Updated: 2024/03/01

Sigma-Aldrich

Product number: P178
Product name: Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity: solid, ≥98% (HPLC)
Packaging: 50mg
Price: $234.6
Updated: 2024/03/01

Cayman Chemical

Product number: 14537
Product name: PPADS (sodium salt)
Purity: ≥95%
Packaging: 10mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 14537
Product name: PPADS (sodium salt)
Purity: ≥95%
Packaging: 50mg
Price: $183
Updated: 2024/03/01

Sigma-Aldrich

Product number: P178
Product name: Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate
Purity: solid, ≥98% (HPLC)
Packaging: 250mg
Price: $1610
Updated: 2023/06/20

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PPADS TETRASODIUM SALT Chemical Properties,Usage,Production

Uses

P2X and P2Y purinergic receptors are ATP-sensitive receptors responsible for mediating a large variety of excitatory postsynaptic responses including fast transmission at central synapses, contraction of smooth muscle cells, platelet aggregation, macrophage activation, and apoptosis. PPADS is a non-selective P2 purinergic antagonist that blocks recombinant P2X1-5 (IC50s = 1-2.6 μM), native P2Y2-like (IC50 = ~0.9 mM), and recombinant P2Y4 (IC50 = ~15 mM) receptors. PPADS antagonism of ATP-sensitive P2 receptors produces neuroprotective effects in an ischemia model with permanent middle cerebral artery occlusion in spontaneously hypertensive rats.

Uses

PPADS Tetrasodium is an non-selective purinergic antagonists of P2 ATP receptors. PPADS Tetrasodium is also a potential neuroprotective agents for the treatment of autoimmune and demyelinating disease.

Definition

ChEBI: Tetrasodium 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate is an organic sodium salt that is the tetrasodium salt of 5'-phosphopyridoxal-6-azobenzene-2,4-disulfonic acid It has a role as a purinergic receptor P2X antagonist. It is an organic sodium salt and an organosulfonate salt. It contains a 5'-phosphonatopyridoxal-6-azobenzene-2,4-disulfonate.

storage

-20°C (desiccate)

PPADS TETRASODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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PPADS TETRASODIUM SALT Suppliers

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192575-19-2, PPADS TETRASODIUM SALTRelated Search:

Pyridoxal phosphate PPADS TETRASODIUM SALT ISO-PPADS TETRASODIUM SALT

PPADS Tetrasodium

PPADS tetrasodium salt, anhydrous

PPADS (sodium salt)

4-[(2E)-2-[4-formyl-6-methyl-5-oxo-3-(phosphonatooxymethyl)pyridin-2-ylidene]hydrazinyl]benzene-1,3-disulfonate

PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULFONIC ACID TETRASODIUM SALT

PYRIDOXALPHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID 4NA

PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DISULPHONIC ACID TETRASODIUM

PPADS

PPADS TETRASODIUM SALT

pyridoxal-phosphate-6-azophenyl-2',4'- disulfoni

PYRIDOXAL-PHOSPHATE-6-AZOPHENYL-2',4'-DI -SULPHONIC ACID TETRAS

PPADS hydrate tetrasodium salt, 4-[[4-Formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]azo]-1,3-benzenedisulfonic acid tetrasodium salt

Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) hydrate tetrasodium salt

4-[[4-FORMYL-5-HYDROXY-6-METHYL-3-[(PHOSPHONOOXY)METHYL]-2-PYRIDINYL]AZO]-1,3-BENZENEDISULFONIC ACID TETRASODIUM

PPADS tetrasodium salt hydrate

Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate

4'-disulfonic acid

Pyridoxalphosphate-6-azophenyl-2'

192575-19-2

C14H10N3Na4O12PS2

Adenosines/P2 Nucleotide Receptor - Antagonists

Adenosines/P2 Nucleotide Receptors (Purinergics)

GPCR Modulators

GPCR Proteins

Ligand-Gated Ion Channels

Membrane Protein Biology Tools

Modulators and Antibodies

P2X Receptor Modulators

Proteins and Derivatives

Aldehydes

Antagonists

Bioactive Small Molecules

Biochemicals and Reagents

Building Blocks

C13-C60

Carbonyl Compounds

Cell Biology

Cell Signaling and Neuroscience

Chemical Synthesis

Ion Channels

Neuroscience

Neurotransmission

Neurotransmitters

Organic Building Blocks

P