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TRANS-4-AMINOCROTONIC ACID

Product Name
TRANS-4-AMINOCROTONIC ACID
CAS No.
38090-53-8
Chemical Name
TRANS-4-AMINOCROTONIC ACID
Synonyms
Afatinib Impurity 71;Afatinib impurity 42;rans-4-Aminocrotonicaci;TRANS-4-AMINOCROTONIC ACID;(E)-4-AMINO-2-BUTENOIC ACID;(E)-4-aminobut-2-enoic acid;2-Butenoic acid, 4-amino-, (2E)-;trans-4-Aminocrotonic acid, TACA;(6r-trans)-7-amino-8-oxo-3-[(1h-1,2,3-triazol-4-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
CBNumber
CB0758206
Molecular Formula
C4H7NO2
Formula Weight
101.1
MOL File
38090-53-8.mol
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TRANS-4-AMINOCROTONIC ACID Property

Melting point:
174-176 °C (decomp)
Boiling point:
300.4±25.0 °C(Predicted)
Density 
1.169±0.06 g/cm3(Predicted)
storage temp. 
Store at RT
solubility 
H2O: >20 mg/mL
form 
solid
pka
3.65±0.10(Predicted)
color 
white
Water Solubility 
Soluble to 100 mM in water
Stability:
Light Sensitive, Temperature Sensitive, Unstable in Solution
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
T004010
Product name
TACA
Packaging
10mg
Price
$65
Updated
2021/12/16
ApexBio Technology
Product number
B6217
Product name
TACA
Packaging
10mg
Price
$188
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004306
Product name
TACA
Purity
95.00%
Packaging
10MG
Price
$648.83
Updated
2021/12/16
ApexBio Technology
Product number
B6217
Product name
TACA
Packaging
50mg
Price
$795
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
API0004306
Product name
TACA
Purity
95.00%
Packaging
50MG
Price
$976.27
Updated
2021/12/16
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TRANS-4-AMINOCROTONIC ACID Chemical Properties,Usage,Production

Uses

TACA is a GABAA?and GABAC?agonist or antagonist for use in the treatment of vascular diseases, also used in the studies on cancer vaccines and carbohydrate epitopes.

Biological Activity

The trans-isomer of CACA. Potent GABA A agonist, GABA uptake inhibitor and substrate for GABA-T. Also GABA C agonist.

in vivo

TACA is a potent competitive inhibitor of GABA uptake in rat brain slices and thus is possibly a substrate for the GABA uptake system[3].

storage

Store at RT

TRANS-4-AMINOCROTONIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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38090-53-8, TRANS-4-AMINOCROTONIC ACIDRelated Search:


  • (E)-4-AMINO-2-BUTENOIC ACID
  • (6r-trans)-7-amino-8-oxo-3-[(1h-1,2,3-triazol-4-ylthio)methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • TRANS-4-AMINOCROTONIC ACID
  • trans-4-Aminocrotonic acid, TACA
  • Afatinib impurity 42
  • Afatinib Impurity 71
  • 2-Butenoic acid, 4-amino-, (2E)-
  • (E)-4-aminobut-2-enoic acid
  • rans-4-Aminocrotonicaci
  • 38090-53-8
  • BioChemical
  • Cell Biology
  • Cell Signaling and Neuroscience
  • Ligand-Gated Ion Channels
  • Ion Channels
  • GABA and Glycine Receptor Modulators
  • GABA/Glycine receptor