6-Iodoquinoline

Product Name: 6-Iodoquinoline
CAS No.: 13327-31-6
Chemical Name: 6-Iodoquinoline
Synonyms: 6-IodoquinoL;6-Iodchinolin;6-lodoquinoline;6-Iodoquinolone;6-IODOQUINOLINE;Quinoline, 6-iodo-;6-Iodoquinoline>6-Iodo-1-azanaphthalene;6-Iodoquinoline ISO 9001：2015 REACH
CBNumber: CB0762146
Molecular Formula: C9H6IN
Formula Weight: 255.06
MOL File: 13327-31-6.mol

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6-Iodoquinoline Property

Melting point:: 91°C
Boiling point:: 120 °C(Press: 1 Torr)
Density: 1.7856 (estimate)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: soluble in Methanol
form: powder to crystal
pka: 4.23±0.10(Predicted)
color: White to Light yellow to Light orange
InChIKey: WKTASELJZCIVBR-UHFFFAOYSA-N
CAS DataBase Reference: 13327-31-6

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Safety

Hazard Codes: Xn
Risk Statements: 22-41
Safety Statements: 26-24/25
WGK Germany: 3
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 731412
Product name: 6-Iodoquinoline
Packaging: 500mg
Price: $67.74
Updated: 2025/07/31

TCI Chemical

Product number: I0931
Product name: 6-Iodoquinoline
Purity: min. 98.0 %
Packaging: 1G
Price: $45
Updated: 2025/07/31

TRC

Product number: I737105
Product name: 6-Iodoquinolone
Packaging: 100mg
Price: $75
Updated: 2021/12/16

SynQuest Laboratories

Product number: 3H32-H-06
Product name: 6-Iodoquinoline
Purity: 98%
Packaging: 250mg
Price: $21
Updated: 2021/12/16

Matrix Scientific

Product number: 073400
Product name: 6-Iodoquinoline
Purity: 95+%
Packaging: 1g
Price: $34
Updated: 2021/12/16

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6-Iodoquinoline Chemical Properties,Usage,Production

Uses

Reactant for:

Room temperature CuI-catalyzed N-arylation using 2-pyridinyl β-ketones ligands

Synthesis

5332-25-2

13327-31-6

General procedure for the synthesis of 6-iodoquinoline from 6-bromoquinoline: sodium iodide (4.32 g, 28.8 mmol), copper(I) iodide (137 mg, 0.72 mmol), N,N'-dimethyl-cyclohexane-1,2-diamine (0.227 mL, 1.44 mmol) and 6-bromoquinoline (3 g, 14.4 mmol) in a solution of dioxane (15 mL). The reaction tube was flushed with nitrogen and sealed with a PTFE septum. Nitrogen was bubbled into the solution through a needle for 10 min to ensure that gas escaped through the needle. After removing the needle, the reaction mixture was stirred at 110°C for 15 hours. Upon completion of the reaction, the green suspension was cooled to room temperature, poured into ice water and extracted with dichloromethane. The organic layer was collected, dried with anhydrous magnesium sulfate, filtered and concentrated in vacuum. The crude product was purified by silica gel column chromatography, eluting sequentially with 100% dichloromethane and dichloromethane/methanol (95:5, v/v) to afford 3.56 g (97% yield) of 6-iodoquinoline as a light yellow solid.1H-NMR (DMSO-d6) δ: 8.93 (1H, dd, J = 1.5, 4.1 Hz), 8.47 (1H, d, J = 2.0 Hz ), 8.33 (1H, d, J = 8.6 Hz), 8.02 (1H, dd, J = 2.0, 8.6 Hz), 7.80 (1H, d, J = 8.6 Hz), 7.56 (1H, dd, J = 4.1, 8.6 Hz).

References

[1] Patent: WO2007/75567, 2007, A1. Location in patent: Page/Page column 117-118
[2] Patent: WO2011/18454, 2011, A1. Location in patent: Page/Page column 63-64
[3] Patent: WO2011/20861, 2011, A1. Location in patent: Page/Page column 69
[4] Patent: WO2008/155378, 2008, A1. Location in patent: Page/Page column 70-71
[5] Patent: CN104250257, 2017, B. Location in patent: Paragraph 0258-0260

6-Iodoquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Iodoquinoline Suppliers

Canada 1 China 143 Europe 1 France 2 Germany 3 India 10 Japan 1 Switzerland 2 The Netherlands 1 Ukraine 2 United Kingdom 7 United States 22 Global 195

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

ChangShu Haitian Fine Chemicals Co.,Ltd

Tel: 13913622609
Fax: 86-512-52893680
Email: 974295387@qq.com
Country: China
ProdList: 192
Advantage: 61

ShangHai DEMO Chemical Co.,Ltd

Tel: 400-021-7337 2355568890
Fax: 0086-21-50182339
Email: sales@demochem.com
Country: China
ProdList: 2572
Advantage: 57

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
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Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
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Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Tetranov Biopharm

Tel: 13526569071
Email: sales@leadmedpharm.com
Country: China
ProdList: 7892
Advantage: 64

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View Lastest Price from 6-Iodoquinoline manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 6-Iodchinolin 13327-31-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-06

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: 6-Iodchinolin 13327-31-6
Price: US $10.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-06-06

Henan Aochuang Chemical Co.,Ltd.

Product: 6-Iodoquinoline 13327-31-6
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

13327-31-6, 6-IodoquinolineRelated Search:

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6-IODOQUINOLINE

6-Iodo-1-azanaphthalene

6-Iodoquinoline&gt

6-IodoquinoL

Quinoline, 6-iodo-

6-Iodoquinoline ISO 9001：2015 REACH

6-Iodchinolin

6-Iodoquinolone

6-lodoquinoline

13327-31-6

C9H6N

Halides

Quinolines, Isoquinolines & Quinoxalines

pharmacetical