(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Reactions

Product Name: (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
CAS No.: 112022-83-0
Chemical Name: (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole
Synonyms: (R)-2-METHYL-CBS-OXAZABOROLIDINE;(R)-ME CBS;(R)-METHYL OXAZABOROLIDINE;(R)-1-Methyl-3,3-diphenylhexahydropyrrolo[1,2-c][1,3,2]oxazaborole;idine;(R)-Me-CBS Catalyst;2-c][1;(R)-1-METH;3H-pyrrolo[1;2]oxazaborole
CBNumber: CB0763916
Molecular Formula: C18H20BNO
Formula Weight: 277.17
MOL File: 112022-83-0.mol

More

Less

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Property

Melting point:: 85-95 °C(lit.)
Boiling point:: 111 °C
Density: 0.95 g/mL at 25 °C
refractive index: 68 ° (C=1, MeOH)
Flash point:: 40 °F
storage temp.: room temp
solubility: soluble in Chloroform, Methanol
pka: 1.02±0.40(Predicted)
form: Liquid
color: Colorless to amber
optical activity: [α]22/D +76.8°, c = 1 in toluene
Water Solubility: Not miscible or difficult to mix in water.
Sensitive: Air & Moisture Sensitive
BRN: 9059874
Exposure limits: ACGIH: TWA 20 ppm
OSHA: Ceiling 300 ppm; TWA 200 ppm
NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)
InChIKey: VMKAFJQFKBASMU-QGZVFWFLSA-N
CAS DataBase Reference: 112022-83-0(CAS DataBase Reference)

More

Less

Safety

Hazard Codes: F,Xn,Xi
Risk Statements: 11-38-48/20-63-65-67-36/37-19-40
Safety Statements: 36/37-62-33-29-16-2-26
RIDADR: UN 1294 3/PG 2
WGK Germany: 3
F: 10
HazardClass: 3
PackingGroup: II
HS Code: 29319090

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H318Causes serious eye damage

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P501Dispose of contents/container to..…

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 457698
Product name: (R)-(+)-2-Methyl-CBS-oxazaborolidine solution
Purity: 1 M in toluene
Packaging: 5ml
Price: $110
Updated: 2024/03/01

Sigma-Aldrich

Product number: 457698
Product name: (R)-(+)-2-Methyl-CBS-oxazaborolidine solution
Purity: 1 M in toluene
Packaging: 25ml
Price: $408
Updated: 2024/03/01

TCI Chemical

Product number: D2130
Product name: (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Purity: >97.0%(T)
Packaging: 1g
Price: $40
Updated: 2024/03/01

TCI Chemical

Product number: D2130
Product name: (R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborolidine
Purity: >97.0%(T)
Packaging: 5g
Price: $116
Updated: 2024/03/01

Alfa Aesar

Product number: L09230
Product name: (R)-2-Methyl-CBS-oxazaborolidine monohydrate, 94%
Packaging: 1g
Price: $83.5
Updated: 2021/12/16

More

Less

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Chemical Properties,Usage,Production

Reactions

Convenient catalyst for the enantioselective borane reduction of ketones at ambient temperatures.
Asymmetric synthesis of α-chiral hydroxyalkylphosphines via a catalytic, enantioselective reduction of acylphosphines.
Nickel-catalyzed cross-couplings of benzylic pivalates with arylboroxines: Stereospecific formation of diarylalkanes and triarylmethanes.
Enantioselective reduction of prochiral ketones with NaBH4/Me2SO4/(S)-Me-CBS.

Chemical Properties

white to light yellow crystal powde

Uses

suzuki reaction

Uses

(R)-2-Methyl-CBS-oxazaborolidine is used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols. It is also used in a desymmetrizing reduction leading to (S)-4-hydroxycyclohexenone. It is useful in the production of stereospecific motifs such as α-hydroxy acids, α-amino acids, symmetrical ferrocenyl diols and propargyl alcohols.

Uses

CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Preparation Products And Raw materials

Raw materials

Preparation Products

4H-AMINO-6-BROMO-2,3-DIHYDROTHIOCHROMEN-1,1-DIOXIDE 4-Hydroxy-6-bromo-2,3-dihydrothiochromen-1,1-dioxide

More

Less

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Suppliers

Americas 1 Belgium 2 China 223 Europe 2 Germany 4 India 22 Japan 4 Russia 2 Slovakia 1 Switzerland 2 The Netherlands 1 United Kingdom 11 United States 32 Global 307

TCI Chemicals (India) Pvt. Ltd.

Tel: --
Fax: --
Email: sales-in@tcichemicals.com
Country: India
ProdList: 6768
Advantage: 58

Manus Aktteva

Tel: --
Fax: --
Email: info@manusaktteva.in
Country: India
ProdList: 581
Advantage: 34

Alfa Aesar

Tel: --
Fax: --
Email: tech@alfa.com
Country: India
ProdList: 6905
Advantage: 58

Siddhi Specialities

Tel: --
Fax: --
Email: siddhispecialities@gmail.com
Country: India
ProdList: 162
Advantage: 58

Atul Bioscience Ltd (ABL)

Tel: --
Fax: --
Email: pharma@atul.co.in
Country: India
ProdList: 26
Advantage: 58

Pharma Direct International

Tel: --
Fax: --
Email: pharmadirectintl@gmail.com
Country: India
ProdList: 44
Advantage: 58

VASIN BIO LIFE SCIENCES PVT LTD

Tel: --
Fax: --
Email: info@vasinbio.com
Country: India
ProdList: 2092
Advantage: 58

Manus Aktteva Biopharma LLP

Tel: --
Fax: --
Country: India
ProdList: 655
Advantage: 58

Atlanta Associates

Tel: --
Fax: --
Country: India
ProdList: 184
Advantage: 58

Chaturya Biotech (Tanuj Life Sciences)

Tel: --
Fax: --
Email: info@chaturyabiotech.com
Country: India
ProdList: 398
Advantage: 58

Atul Limited - PP Site

Tel: --
Fax: --
Country: India
ProdList: 23
Advantage: 58

Nchem Laboratories

Tel: --
Fax: --
Country: India
ProdList: 156
Advantage: 58

S. Amit Speciality Chemicals Pvt. Ltd.

Tel: --
Fax: --
Email: gupta@s-amit.com
Country: India
ProdList: 177
Advantage: 58

ALTAIR ALCHEMY Laboratories

Tel: --
Fax: --
Email: altair@altair-alchemy.com
Country: India
ProdList: 324
Advantage: 58

Hrishabh Life Sciences

Tel: --
Fax: --
Email: info@hrishabhlife.com
Country: India
ProdList: 158
Advantage: 58

Hychem Laboratories

Tel: --
Fax: --
Email: info@hychemlabs.com
Country: India
ProdList: 105
Advantage: 58

A.J Chemicals

Tel: --
Fax: --
Email: sales@ajchem.in
Country: India
ProdList: 6100
Advantage: 58

Avra Synthesis Pvt Ltd

Tel: --
Fax: --
Email: info@avrasynthesis.com
Country: India
ProdList: 1603
Advantage: 30

CHEMSWORTH

Tel: --
Fax: --
Email: info@chemsworth.com
Country: India
ProdList: 6700
Advantage: 30

More

Less

View Lastest Price from (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 112022-83-0
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 5tons
Release date: 2021-11-09

Henan Aochuang Chemical Co.,Ltd.

Product: (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 112022-83-0
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-09-26

Zhuozhou Wenxi import and Export Co., Ltd

Product: (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole 112022-83-0
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-08-11

112022-83-0, (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaboroleRelated Search:

2-Methyl-1-propanol Piperazine n-Butyllithium Potassium pyrophosphate Tetrahydrofuran Benzoic acid Sodium sulfide 2-Amino-2-methyl-1-propanol CATECHOLBORANE N-Benzylcinchonidinium chloride ent-EzetiMibe EzetiMibe (3R,4R,3'S)-IsoMer (R)-3-((S)-5-(4-fluorophenyl)-5-hydroxypentanoyl)-4-phenyloxazolidin-2-one (3R,4R)-1-(4-fluorophenyl)-3-((R)-3-(4-fluorophenyl)-3-hydroxypropyl)-4-(4-hydroxyphenyl)azetidin-2-one 4a€-O-Benzyloxy (3S,4S)-Ezetimibe (4S)-3-(2,2-dimethylpropanoyl)-4-phenyl-1,3-oxazolidin-2-one 4-BENZOYLBUTYRIC ACID 2-Oxazolidinone, 3-[(2R,5S)-5-(4-fluorophenyl)-2-[(S)-[(4-fluorophenyl)amino][4-[(trimethylsilyl)oxy]phenyl]methyl]-1-oxo-5-[(trimethylsilyl)oxy]pentyl]-4-phenyl-, (4S)-rel-

ALPHA,ALPHA-DIPHENYL-D-PROLINOL METHYLBORONIC ACID CYCL-AMIDE-ESTER

(R)-(+)-2-METHYL-CBS-OXAZABOROLIDINE

(R)-Methyloxazaborolidine,1-1.5Mintoluene[(R)-MeCBS]CoreyCatalyst

(r)-(+)-2-methyl-cbs-oxazaborolidine solution

(r)-2-methyl-cbs-oxazaborolidine, 1m soln. in toluene

α,α-diphenyl-d-prolinol methylboronic acid cycl-amide-ester

α,α-diphenyl-d-prolinolmethylboronic acid cyclamide ester

(R)-(+)-Methyl-CBS-oxazaborolidine

(R)-Me-CBS Catalyst

α,α-Diphenyl-D-prolinolmethylboronic acid cyclamide ester, (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, (R)-1-Methyl,3,3-diphenyl-tetrahydro-pyrrolo(1,2-c)(1,3,2)oxazaborole

(R-Methyl-Corey-Bakshi-Shibata catalyst

(R)-Tetrahydro-1-methyl-3,3-triphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 1-1.5M in toluene [(R)-Methyl oxazaborolidine] Corey Catalyst

(3aR)-1-Methyl-3,3-diphenyl-3aα,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole

(3aR)-3,3aα,4,5-Tetrahydro-1-methyl-3,3-diphenyl-6H-1-bora-2-oxa-6a-azapentalene

(3aR)-3,3-Diphenyl-1-methyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole

(3aR)-Tetrahydro-1-methyl-3,3-diphenyl-3H-pyrrolo[1,2-c][1,3,2]oxazaborole

(5R)-2-Methyl-4,4-diphenyl-1-aza-2-bora-3-oxabicyclo[3.3.0]octane

1-Methyl-3,3-diphenyl-3aα,4,5,6-tetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole

(R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(R)-TETRAHYDRO-1-METHYL-1,3-DIPHENYL-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZOBOROLE

(R)-(+)-2-Methyl-CBS-oxazaborolidine >=95%

(R)-(+)-2-Methyl-CBS-oxazaborolidine solution 1 M in THF

(R)-(+)-2-Methyl-CBS-oxazaborolidine solution 1 M in toluene

(R)-(+)-2-Methyl-CBS-oxazaborolindine

(R)-2-Methyl-CBS-oxazaborolidine (R)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(R)-2-Methyl-CBS-oxazaborolidine (1mol/L)

(R)-2-Methyl-CBS-oxazaborolidine (solid)

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine]

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine] (R)-CBS Catalyst

(R)- METHYL OXAZABOROLIDINE IN TOLUENE 1M. IN CYLINDER

(R)-1-METHYL,3,3-

(R)-1-METH

(R)-2-METHYL-CBS-OXAZABOROLIDINE

(R)-2-METHYL-CBS-OXAZABOROLIDINE MONOHYDRATE

(R)-1-METHYL,3,3-DIPHENYL-TETRAHYDRO-PYRROLO(1,2-C)(1,3,2)OXAZABOROLE

(R)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZABOROLE

(R)-3,3-DIPHENYL-1-METHYLTETRAHYDRO-3H-PYRROLO-[1,2-C][1,3,2]OXAZABOROLE

(R)-5,5-DIPHENYL-2-METHYL-3,4-PROPANO-1,3,2-OXAZABOROLIDINE

(R)-TETRAHYDRO-1-METHYL-3,3-DIPHENYL-1H,3H-PYRROLO[1,2-C][1,3,2] OXAZABOROLE

(R)-TETRAHYDRO-1-METHYL-3,3-DIPHENYL-1H,3H-PYRROLO[1,2-C][1,3,2]OXAZOBOROLE

(R)-ME CBS

(R)-METHYL OXAZABOROLIDINE

(R)-methyloxazaborolidine,(R)-mecbs,in

(R)-methyloxazaborolidine,(R)-mecbs,intoluene

(R)-Methyloxazaborolidine,1-1.5Mintoluene[(R)-MeCBS]

( R )-2-Methyl-CBS-Oxazaborolidine.H20

(R)-Methyl oxazaborolidine, in toluene, 1M solution

(R)-(+)-2-METHYL-CBS-OXAZABOROLIDINE, 1M SOLUTION IN TOLUENE

(R)-2-METHYL-CBS-OXAZABOROLIDINE, 1M IN&

(R)-5,5-Diphenyl-2-methyl-3,4-propano-1,3,2-oxazaborlidine

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole,0.9-1.1Mintoluene[(R)-Methyloxazaborolidine]CoreyCatalyst

(R)-Tetrahydro-1-Methyl-3

0.9-1.1Mintoluene[(R)-Methyloxazaborolidine]CoreyCatalyst

2]oxazaborole

2-c][1

3-diphenyl-1H

3H-pyrrolo[1

(R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrole[1,2-c][1,3,2]oxazaborole, 0.9-1.1M in toluene [(R)-Methyloxazaborolidine] Corey Catalyst