BOC-BETA-ALA-OSU
- Product Name
- BOC-BETA-ALA-OSU
- CAS No.
- 32703-87-0
- Chemical Name
- BOC-BETA-ALA-OSU
- Synonyms
- Boc-β-Ala-Osu;BOC-BETA-ALA-OSU;Boc-L-Beta-Ala-Osu;BOC-BETA-ALANINE-OSU;BOC-B-ALANINE HYDROXYSUCCINIMIDESTER;Boc-β-alanine N-hydroxysuccinimide ester;BOC-BETA-ALANINE HYDROXYSUCCINIMIDE ESTER;N-Boc-^b-alanine N-succinimidyl ester, 98%;BOC-BETA-ALANINE N-HYDROXYSUCCINIMIDE ESTER;N-Boc-beta-alanine N-hydroxysuccinimide ester
- CBNumber
- CB0766452
- Molecular Formula
- C12H18N2O6
- Formula Weight
- 286.28
- MOL File
- 32703-87-0.mol
BOC-BETA-ALA-OSU Property
- Melting point:
- 100-101 °C
- Density
- 1.28±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 11.98±0.46(Predicted)
- Appearance
- White to off-white Solid
- CAS DataBase Reference
- 32703-87-0
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- B619545
- Product name
- Boc-β-Ala-OSu
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- 03778
- Product name
- Boc-β-alanineN-hydroxysuccinimideester,≥98%(HPLC)
- Purity
- ≥98%(HPLC)
- Packaging
- 25G
- Price
- $69.89
- Updated
- 2021/12/16
- Product number
- FB47798
- Product name
- Boc-b-alanine N-hydroxysuccinimide ester
- Packaging
- 10g
- Price
- $80
- Updated
- 2021/12/16
- Product number
- FB47798
- Product name
- Boc-b-alanine N-hydroxysuccinimide ester
- Packaging
- 25g
- Price
- $125
- Updated
- 2021/12/16
- Product number
- 093822
- Product name
- Boc-Beta-Ala-OSu
- Purity
- 95+%
- Packaging
- 100g
- Price
- $162
- Updated
- 2021/12/16
BOC-BETA-ALA-OSU Chemical Properties,Usage,Production
Chemical Properties
White to off-white powder
Uses
Boc-beta-Ala-OSu
Synthesis
6066-82-6
3303-84-2
32703-87-0
In a dry reaction flask equipped with a magnetic stirrer, Boc-β-alanine (0.50 g, 2.64 mmol) and N-hydroxybutanediimide (0.31 g, 2.72 mmol, 1.03 equiv) were dissolved in 3 mL of anhydrous dioxane. Subsequently, 1.25 equivalents of 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride (EDC-HCl, 0.63 g, 3.3 mmol) was added. The reaction solution became turbid and 2 mL of anhydrous dioxane was added additionally. The reaction mixture was stirred under nitrogen protection for 30 min, followed by continued stirring at room temperature overnight. Upon completion of the reaction, the solvent was evaporated under reduced pressure. The residue was dissolved with chloroform and washed three times (3×) with water. The organic layer was dried over anhydrous sodium sulfate and concentrated under reduced pressure. The resulting product was recrystallized in ethanol and dried in a desiccator to afford 2,5-dioxopyrrolidin-1-yl 3-((tert-butoxycarbonyl)amino)propionate (0.47 g, 62% yield). The 1H NMR spectral data of the product were in agreement with those reported in the literature.
References
[1] ACS Medicinal Chemistry Letters, 2018, vol. 9, # 6, p. 557 - 561
[2] Patent: WO2017/53486, 2017, A1. Location in patent: Page/Page column 11
[3] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981, p. 529 - 537
[4] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 24, p. 3603 - 3608
[5] Chemical Communications, 2010, vol. 46, # 20, p. 3553 - 3555
BOC-BETA-ALA-OSU Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-BETA-ALA-OSU Suppliers
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View Lastest Price from BOC-BETA-ALA-OSU manufacturers
- Product
- BOC-BETA-ALA-OSU 32703-87-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20T
- Release date
- 2024-08-01
- Product
- BOC-BETA-ALA-OSU 32703-87-0
- Price
- US $9.80/KG
- Min. Order
- 1g
- Purity
- ≥99%
- Supply Ability
- 100kg
- Release date
- 2020-01-10