3-(BOC-AMINO)-1-PROPANOL

Product Name: 3-(BOC-AMINO)-1-PROPANOL
CAS No.: 58885-58-8
Chemical Name: 3-(BOC-AMINO)-1-PROPANOL
Synonyms: Boc-NH-Pr-OH;Zinc02556980;Boc-b-Ala-ol;Boc-β-Ala-ol;Boc-β-Alaninol;BOC-BETA-ALA-OL;Boc-Bata-Ala-ol;BOC-NH-(CH2)3-OH;3-(BOC-AMINO)PROPANOL;BOC-3-AMINO-1-PROPANOL
CBNumber: CB7301634
Molecular Formula: C8H17NO3
Formula Weight: 175.23
MOL File: 58885-58-8.mol

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3-(BOC-AMINO)-1-PROPANOL Property

Boiling point:: 293℃
Density: 1.025 g/mL at 20 °C(lit.)
refractive index: n20/D 1.453
Flash point:: >230 °F
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Sparingly), Methanol (Sparingly)
form: clear liquid
pka: 12.57±0.46(Predicted)
color: Colorless to Almost colorless
BRN: 1860807
InChI: InChI=1S/C8H17NO3/c1-8(2,3)12-7(11)9-5-4-6-10/h10H,4-6H2,1-3H3,(H,9,11)
InChIKey: XDJCYKMWJCYQJM-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)NCCCO
CAS DataBase Reference: 58885-58-8(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 23-24/25-37/39-26
WGK Germany: 3
F: 10-21
HS Code: 29241990

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 416444
Product name: 3-(Boc-amino)-1-propanol
Purity: 97%
Packaging: 10ml
Price: $75.71
Updated: 2025/07/31

Sigma-Aldrich

Product number: 416444
Product name: 3-(Boc-amino)-1-propanol
Purity: 97%
Packaging: 50ml
Price: $292
Updated: 2025/07/31

TCI Chemical

Product number: H0900
Product name: 3-(tert-Butoxycarbonylamino)-1-propanol
Purity: >96.0%(GC)
Packaging: 5mL
Price: $41
Updated: 2025/07/31

TCI Chemical

Product number: H0900
Product name: 3-(tert-Butoxycarbonylamino)-1-propanol
Purity: >96.0%(GC)
Packaging: 25mL
Price: $116
Updated: 2025/07/31

TRC

Product number: B619275
Product name: N-Boc-3-aminopropanol
Packaging: 25g
Price: $155
Updated: 2021/12/16

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3-(BOC-AMINO)-1-PROPANOL Chemical Properties,Usage,Production

Chemical Properties

colorless to yellow or brown liquid

Uses

Amine protected, difunctional reagent employed in the synthesis of phosphatidyl ethanolamines and ornithine.

reaction suitability

reagent type: cross-linking reagent

Synthesis

24424-99-5

156-87-6

58885-58-8

General procedure for the synthesis of tert-butyl N-(3-hydroxypropyl)carbamate: 1. an anhydrous dichloromethane (DCM, 50 mL) solution of di-tert-butyl dicarbonate ((Boc)2O, 25.0 g, 114.5 mmol) was added slowly and dropwise under nitrogen protection to an anhydrous DCM solution (100 mL) of 3-amino-1-propanol (41, 7.8 g, 104.5 mmol) under stirring. 2. The reaction mixture was stirred at room temperature for 12 h. The progress of the reaction was monitored by thin layer chromatography (TLC, 50% petroleum ether/ethyl acetate) to confirm complete consumption of the feedstock. 3. Upon completion of the reaction, the reaction solution was diluted with ether (Et2O, 150 mL) and washed sequentially with phosphate buffer (0.5 M, pH 5.4, 2 × 70 mL), saturated aqueous sodium bicarbonate (70 mL) and brine (2 × 70 mL). 4. The organic phase was dried with anhydrous magnesium sulfate (MgSO4), filtered and the excess solvent was removed by evaporation under reduced pressure to afford the colorless viscous oily product tert-butyl N-(3-hydroxypropyl)carbamate (42, 18.3 g, 100% yield). Product characterization data: 1H NMR (270 MHz, CDCl3): δ 1.44 (s, 9H, CH3), 1.67 (m, 2H, H2'), 3.26 (q, 2H, J = 6.23 Hz, H3'), 3.65 (dd, 2H, J = 5.86, 5.68 Hz, H1'), 3.78 (dt, 1H, J = 6.04, 5.87 Hz, OH), 5.18 (br, 1H, NH). 13C NMR (67.8 MHz, CDCl3): δ 28.4 (CH3), 32.6 (C2'), 37.1 (C3'), 59.3 (C1'), 79.4 (Cquater), 157.1 (CO); MS (E/I) m/l, 1H, J = 6.04, 5.87 Hz, OH, 5.18 (br, 1H, NH). MS (E/I) m/z (relative strength): 176 (M+, 30), 120 (100), 119 (31), 102 (49), 83 (33), 76 (67), 74 (36). HRMS (E/I) Calculated value C8H17O3N: m/e 175.1200, measured value m/e 175.1208; IR (Nujol) ν IR (Nujol) ν (cm-1): 3355, 2976, 2936, 2878, 1810, 1694, 1531, 1455, 1392, 1366, 1278, 1253, 1173, 1072, 996, 914, 870, 781, 752, 638.

References

[1] Synthesis, 1990, p. 366 - 368
[2] Bioorganic and Medicinal Chemistry Letters, 1998, vol. 8, # 21, p. 3059 - 3064
[3] Patent: US6414148, 2002, B1
[4] Patent: US6747144, 2004, B1. Location in patent: Page column 28
[5] Patent: US2010/222324, 2010, A1. Location in patent: Page/Page column 50

3-(BOC-AMINO)-1-PROPANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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3-(BOC-AMINO)-1-PROPANOL Suppliers

Americas 1 Belgium 1 China 169 Europe 1 France 1 Germany 5 India 6 Italy 1 Japan 3 Slovakia 1 Switzerland 4 United Kingdom 7 United States 28 Global 228

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View Lastest Price from 3-(BOC-AMINO)-1-PROPANOL manufacturers

Henan Aochuang Chemical Co.,Ltd.

Product: 3-(BOC-AMINO)-1-PROPANOL 58885-58-8
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-13

Career Henan Chemical Co

Product: 3-(BOC-AMINO)-1-PROPANOL 58885-58-8
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 10KG
Release date: 2019-08-05

58885-58-8, 3-(BOC-AMINO)-1-PROPANOLRelated Search:

tert-Butyl N-(3-aminopropyl)-N-methylcarbamate tert-butyl (3-bromo-2-fluorophenyl)carbamate tert-butyl (3-(2-(3-((5-cyanopyrazin-2-yl)amino)-1H-pyrazol-5-yl)-5-fluoro-3-methoxyphenoxy)propyl)carbamate tert-butyl (3-(5-fluoro-2-(isoxazol-5-yl)-3-methoxyphenoxy)propyl)carbamate Boc-Asp-OtBu Boc-Hyp-OH BOC-ASP(OBZL)-OSU Boc-Asp(Ochx)-OH Boc-beta-alanine BOC-HYP(BZL)-OH N-Boc-L-Homoserine Boc-Asp-OH Boc-D-aspartic acid 4-benzyl ester 4-tert-Butyl N-[(tert-butoxy)carbonyl]-L-aspartate dicyclohexylamine salt Boc-D-aspartic acid 4-cyslohexyl ester (R)-1-(Boc-amino)-2-propanol, 98% 2R-BOC-AMINO-1-PROPANOL,(R)-(+)-2-(BOC-AMINO)-1-PROPANOL,(R)-2-(BOC-AMINO)-1-PROPANOL (S)-(-)-2-(BOC-AMINO)-1-PROPANOL,(S)-2-(BOC-AMINO)-1-PROPANOL,(S)-2-(Boc-amino)-1-propanol=N-(tert-Butoxycarbonyl)-L-alaninol

TERT-BUTYL (3-HYDROXYPROPYL)CARBAMATE

TERT-BUTYL N-(3-HYDROXYPROPYL)CARBAMATE

N-(3-HYDROXYPROPYL)CARBAMIC ACID TERT-BUTYL ESTER

N-T-BUTOXYCARBONYL-3-AMINO-1-PROPANOL

N-T-BUTOXYCARBONYL-BETA-ALANINOL

tert-ButylN-(3hydeoxypropyl)carbamate

Boc-NH-Pr-OH

CARBAMIC ACID,(3-HYDROXYPROPYL)-, 1,1-DIMETHYLETHYL ESTER

BOC-NH-(CH2)3-OH

BOC-3-AMINO-1-PROPANOL

BOC-BETA-ALA-OL

LABOTEST-BB LT00452356

3-(T-BUTOXYCARBONYLAMINO)-1-PROPANOL

3-(TERT-BUTOXYCARBONYLAMINO)-1-PROPANOL

(3-HYDROXY-PROPYL)-CARBAMIC ACID TERT-BUTYL ESTER

3-(N-BOC-AMINO) PROPANOL

3-(BOC-AMINO)-1-PROPANOL

3-(BOC-AMINO)PROPANOL

N-t-Butyloxycarbonyl-3-hydroxy-propylamine

3-(BOC-amino)-1-propanol,97%

Zinc02556980

3-(Boc-amino)-1-propanol,tert-Butyl N-(3-hydroxypropyl)carbamate

3-(Boc-amino)-1-propanol tert-Butyl N-(3-Hydroxypropyl)carbamate N-(3-Hydroxypropyl)carbamic Acid tert-Butyl Ester

3-(N-tert-Butoxycarbonylamino)-1-propanol

3-(N-tert-Butoxycarbonylamino)propanol

3-(tert-Butoxycarbonylamino)propanol

Boc-b-Ala-ol

3-(<i>tert</i>-Butoxycarbonylamino)-1-propanol

Carbamic acid, N-(3-hydroxypropyl)-, 1,1-dimethylethyl ester

Boc-β-Alaninol≥ 99% (TLC)

N-tert-Butyloxycarbonyl-3-hydroxy-propylamine

N-Boc-3-amino-1-propanol

3-(Boc-aMino)-1-propanol 97%

N-tert-butoxycarbonyl-3-aminopropanol

tert-butyl-n-(3-hydroypropyl)carbamate

3-(tert-Butoxycarbonylamino)-1-propanol&gt

Boc-β-Ala-ol

Boc-β-Alaninol

Boc-Bata-Ala-ol

tert-Butyl 3-hydroxypropylcarbamate - [B8386]

58885-58-8

CH33COCONHCH2CH2CH2OH

ESTER

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