N-Boc-L-Homoserine

Product Name: N-Boc-L-Homoserine
CAS No.: 41088-86-2
Chemical Name: N-Boc-L-Homoserine
Synonyms: Boc-Hse;Boc-HoSer;BOC-HSE-OH;Boc-HSer-OH;Boc-HoSer-OH;Boc-Homoserine;BOC-HOMOSER-OH;BOC-L-HOMOSERINE;N-Boc-L-homoserine;N-T-BOC-L-HOMOSERINE
CBNumber: CB6226376
Molecular Formula: C9H17NO5
Formula Weight: 219.24
MOL File: 41088-86-2.mol

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N-Boc-L-Homoserine Property

Melting point:: 140°C(lit.)
Boiling point:: 421.6±40.0 °C(Predicted)
Density: 1.204±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Store in freezer, under -20°C
pka: 3.87±0.10(Predicted)
form: powder to crystal
color: White to Almost white
optical activity: Consistent with structure
InChI: InChI=1S/C9H17NO5/c1-9(2,3)15-8(14)10-6(4-5-11)7(12)13/h6,11H,4-5H2,1-3H3,(H,10,14)(H,12,13)/t6-/m0/s1
InChIKey: PZEMWPDUXBZKJN-LURJTMIESA-N
SMILES: C(O)(=O)[C@H](CCO)NC(OC(C)(C)C)=O

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Safety

WGK Germany: 3
HS Code: 2922.49.4950

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: B4645
Product name: Boc-Homoser-OH
Packaging: 1g
Price: $422
Updated: 2023/06/20

Sigma-Aldrich

Product number: B4645
Product name: Boc-Homoser-OH
Packaging: 5g
Price: $1510
Updated: 2023/06/20

TCI Chemical

Product number: B4025
Product name: N-(tert-Butoxycarbonyl)-L-homoserine
Purity: >98.0%(HPLC)(T)
Packaging: 1g
Price: $68
Updated: 2025/07/31

TCI Chemical

Product number: B4025
Product name: N-(tert-Butoxycarbonyl)-L-homoserine
Purity: >98.0%(HPLC)(T)
Packaging: 5g
Price: $271
Updated: 2025/07/31

TRC

Product number: B656230
Product name: N-Boc-L-Homoserine
Packaging: 1g
Price: $155
Updated: 2021/12/16

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N-Boc-L-Homoserine Chemical Properties,Usage,Production

Uses

Protected L-Homoserine (H615010).

Synthesis

672-15-1

24424-99-5

41088-86-2

The general procedure for the synthesis of N-Boc-L-homoserine from L-homoserine and di-tert-butyl dicarbonate was as follows: L-homoserine (4.76 g, 40 mmol) and sodium carbonate (Na2CO3, 8.48 g, 80 mmol) were dissolved in water (200 mL). To this solution, 1,4-dioxane (50 mL) was added and stirred for 5 minutes. Di-tert-butyl dicarbonate (Boc2O, 13.80 mL, 60 mmol) was slowly added to the solution under ice bath conditions, followed by stirring the reaction mixture overnight at room temperature. Upon completion of the reaction, the mixture was washed with petroleum ether to remove unreacted organic matter. Additional water was added to the mixture and the pH was adjusted to 2 with 2 mol/L hydrochloric acid (HCl) to induce precipitation of N-Boc-L-homoserine. The formed suspension was extracted with ethyl acetate (EtOAc), and the organic layers were combined and washed sequentially with water and brine. The organic layer was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated to give the crude product (about 8.55 g).

References

[1] Journal of Organic Chemistry, 1986, vol. 51, # 26, p. 5047 - 5050
[2] Journal of Peptide Science, 2013, vol. 19, # 5, p. 308 - 314
[3] Journal of Organic Chemistry, 2008, vol. 73, # 8, p. 3212 - 3217
[4] Tetrahedron Letters, 2002, vol. 43, # 33, p. 5727 - 5729
[5] Journal of Organic Chemistry, 2003, vol. 68, # 23, p. 8853 - 8858

N-Boc-L-Homoserine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-L-Homoserine Suppliers

Americas 1 Belgium 1 Canada 2 China 149 Europe 1 Germany 3 India 4 Japan 4 Poland 1 South Korea 1 Switzerland 3 United Kingdom 6 United States 26 Global 202

Kanghua (Shanghai) New Drug Development Co., Ltd.

Tel: 021-61263370 18901917034
Email: xingli@glbiochem.com
Country: China
ProdList: 5637
Advantage: 58

HINOVA PHARMACEUTICALS INC.

Tel: 18244267397
Email: cxinghua127@163.com
Country: China
ProdList: 97
Advantage: 58

Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Ark Pharm, Inc.

Tel: 847-367-3680
Fax: 847-367-3681
Email: sales@arkpharminc.com
Country: United States
ProdList: 1670
Advantage: 56

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

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View Lastest Price from N-Boc-L-Homoserine manufacturers

Career Henan Chemical Co

Product: N-Boc-L-Homoserine 41088-86-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100Kg
Release date: 2020-06-30

Career Henan Chemical Co

Product: (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoic acid 41088-86-2
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99
Supply Ability: 100KG
Release date: 2020-06-30

41088-86-2, N-Boc-L-HomoserineRelated Search:

D-Cycloserine tert-Butanol Boc-Ser(tBu)-OH L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE L-Homoserine DL-Serine N-Carbobenzyloxyglycine BOC-HYP-OL N-Boc-L-Phenylalaninol N-Boc-exo-3-aminotropane BOC-D-Methionine N-Boc-D-Phenylalaninol BOC-D-ALPHA-T-BUTYLGLYCINE N-Boc-D-Valino Boc-Lys-OH Boc-Hyp-OH 4-tert-Butyl N-[(tert-butoxy)carbonyl]-L-aspartate dicyclohexylamine salt Boc-Asp-OtBu

N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine

N-Boc-L-homoserine

N-tert-Butoxycarbonyl-L-homoserine

Boc-Homoserine

N-T-BOC-L-HOMOSERINE

N-T-BUTOXYCARBONYL-L-HOMOSERINE

(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoic acid

BOC-L-HOMOSERINE

N-tert-Butoxycarbonyl-L-homoserin

Boc-HoSer-OH

(S)-2-(tert-Butoxycarbonylamino)-4-hydroxybutanoic Acid

(2S)-4-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid

Boc-L-homoserine、Boc-Homoser-OH

BOC-HSE-OH

BOC-HOMOSER-OH

N-(tert-Butoxycarbonyl)-L-homoserine &gt

L-Homoserine, N-[(1,1-dimethylethoxy)carbonyl]-

(S)-2-(Boc-amino)-4-hydroxybutyric Acid

(S)-2-(tert-Butoxycarbonylamino)-4-hydroxybutyric Acid

N-α-(t-Butoxycarbonyl)-L-homoserine

Boc-HoSer

Boc-Hse

Boc-HSer-OH

(tert-butoxy carbonyl)-L-homoserine

41088-86-2

Modified Amino Acids

A - H

Biochemicals and Reagents

Amino Acids and Peptides

BioChemical

Amino Acids & Derivatives

Amino Acid Derivatives