L-Homoserine

Product Name: L-Homoserine
CAS No.: 672-15-1
Chemical Name: L-Homoserine
Synonyms: HOMOSERINE;HSE;(S)-2-AMINO-4-HYDROXYBUTANOIC ACID;H-HOMOSER-OH;H-HSE-OH;H-HOSER-OH;H-HOMOSERINE;(2S)-2-Amino-4-hydroxybutanoic acid;RODH;SDR9C6
CBNumber: CB2854094
Molecular Formula: C4H9NO3
Formula Weight: 119.12
MOL File: 672-15-1.mol

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L-Homoserine Property

Melting point:: 203 °C (dec.)(lit.)
alpha: -8.5 º (c=2, H2O 22 ºC)
Boiling point:: 222.38°C (rough estimate)
Density: 1.3126 (rough estimate)
refractive index: 1.4183 (estimate)
storage temp.: Store below +30°C.
solubility: 1100g/l
pka: 2.71(at 25℃)
form: Crystalline Powder
color: White to light yellow
optical activity: -8.825 (H2O) +18.326 (2 mol dm-3 HCl)
Water Solubility: 1100 g/L (30 ºC)
Merck: 14,4739
BRN: 1721681
InChIKey: UKAUYVFTDYCKQA-VKHMYHEASA-N
LogP: -1.289 (est)
CAS DataBase Reference: 672-15-1(CAS DataBase Reference)

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Safety

Risk Statements: 36/37/38
Safety Statements: 24/25-44-35-26-28-7-4-3/9
WGK Germany: 3
F: 10
HS Code: 29225000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: H6515
Product name: L-Homoserine
Packaging: 1g
Price: $365
Updated: 2024/03/01

Sigma-Aldrich

Product number: H6515
Product name: L-Homoserine
Packaging: 5g
Price: $1720
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.14359
Product name: L-(-)-Homoserine
Purity: for synthesis
Packaging: 1g
Price: $147
Updated: 2024/03/01

TCI Chemical

Product number: H1030
Product name: L-Homoserine
Purity: >98.0%(T)
Packaging: 1g
Price: $62
Updated: 2024/03/01

TCI Chemical

Product number: H1030
Product name: L-Homoserine
Purity: >98.0%(T)
Packaging: 5g
Price: $204
Updated: 2024/03/01

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L-Homoserine Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystalline powder

Uses

L-Homoserine is used in the biosynthesis of methionine, threonine and isoleucine. It is also used as an internal standard for neurotransmitter analysis and amino acids quantification.

Definition

ChEBI: L-homoserine is the L-enantiomer of homoserine. It has a role as a human metabolite, an algal metabolite, a Saccharomyces cerevisiae metabolite and an Escherichia coli metabolite. It is an enantiomer of a D-homoserine. It is a tautomer of a L-homoserine zwitterion.

Synthesis Reference(s)

Journal of the American Chemical Society, 80, p. 3147, 1958 DOI: 10.1021/ja01545a057
The Journal of Organic Chemistry, 24, p. 1794, 1959 DOI: 10.1021/jo01093a610

General Description

L-Homoserine is a variant of serine with an additional carbon on its side chain.

Biochem/physiol Actions

L-Homoserine is synthesized by deoxidation process, catalysed by homoserine dehydrogenase. This is one of the steps in the synthesis of L-threonine. The carbon flux in in bacteria such as E. coli is maintained by this reaction.

Purification Methods

Likely impurities are N-chloroacetyl-L-homoserine, N-chloroacetyl-D-homoserine, L-homoserine, homoserine lactone, homoserine anhydride (formed in strong solutions of homoserine if slightly acidic). It cyclises to the lactone in strongly acidic solution. It crystallises from water by adding 9 volumes of EtOH. [Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 pp 2612-2616 1961, Beilstein 4 IV 3187.]

L-Homoserine Preparation Products And Raw materials

Raw materials

Preparation Products

DL-Threonine L-Lysine hydrochloride

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L-Homoserine Suppliers

Americas 1 Belgium 1 Canada 1 China 372 Europe 3 Germany 9 India 9 Japan 7 Slovakia 1 South Korea 1 Switzerland 1 United Kingdom 13 United States 57 USA 1 Global 477

Shanghai Yurlic Chemical S&T Co.Ltd.

Tel: 021-37285141 15618858630
Fax: 021-37285142
Email: yancf@yulibiotech.com
Country: China
ProdList: 170
Advantage: 58

Wuxi maimo topp biotechnology co., LTD

Tel: 15061806929
Email: linda-fu@mimotopes.cn
Country: China
ProdList: 5834
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Hubei Chanmol Biotech Co., Ltd.

Tel: 0711-3812399 18062309155
Email: 156941107@qq.com
Country: China
ProdList: 3001
Advantage: 58

Anhui Tokind Advanced Material Co., Ltd.

Tel: 0554-2114112 18118134211
Email: tokind@tokinchem.com
Country: China
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Advantage: 58

Wuhan woxuan Technology Co., Ltd

Tel: 13322067656
Email: 3199863540@qq.com
Country: China
ProdList: 5081
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Shanghai Boyle Chemical Co., Ltd.

Tel: 021-50182298 021-50180596
Fax: +86-21-57758967
Email: sales@boylechem.com
Country: China
ProdList: 2208
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J & K SCIENTIFIC LTD.

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Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
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Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
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INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15839
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View Lastest Price from L-Homoserine manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: L-homoserine 672-15-1
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99
Supply Ability: 5000
Release date: 2024-11-14

WUHAN FORTUNA CHEMICAL CO., LTD

Product: L-Homoserine 672-15-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 5000kg/month
Release date: 2021-10-13

Honest Joy Holdings Limited

Product: L-Homoserine 672-15-1
Price: US $0.00/KG
Min. Order: 1KG
Purity: 98.0%
Supply Ability: 100 tons
Release date: 2022-02-18

672-15-1, L-HomoserineRelated Search:

trans-4-Hydroxy-L-proline methyl ester hydrochloride beta-Methyl L-aspartate hydrochloride H-ASP(OTBU)-OTBU HCL Dimethyl L-aspartate hydrochloride H-CIS-HYP-OME HCL H-ASP(OET)-OET HCL L-Threonine DL-4-Amino-3-hydroxybutyric acid L(+)-allo-Threonine allo-DL-Threonine DL-GAMMA-AMINO-B-HYDROXYBUTYRIC ACIDCRYS TALLINE 2-Hydroxy-4-amino butanoic acid (S)-N-Carbobenzyloxy-4-amino-2-hydroxybutyric acid DL-Homoserine (S)-(+)-4-AMINO-3-HYDROXYBUTANOIC ACID D(-)-allo-Threonine H-ASP-OBZL HCL H-ASP(OTBU)-OME HCL

(S)-(-)-2-AMINO-4-HYDROXYBUTYRIC ACID

(S)-2-AMINO-4-HYDROXYBUTYRIC ACID

L-2-AMINO-4-HYDROXYBUTANOIC ACID

L-2-AMINO-4-HYDROXYBUTYRIC ACID

L-2-AMINO-4-HYDROXYBUTYRIC ACID HYDROCHLORIDE

H-L-HSE-OH

H-HSE-OH

H-HOSER-OH

H-HOSER-OH HCL

H-HOMOSER-OH

H-HOMOSERINE

HSE

HOMOSERINE

HOMOSERINE-L

2-AMINO-4-HYDROXYBUTYRIC ACID

L-2-Amino-4-hydroxybutyricacid=H-Hser-OH

(S)-2-AMINO-4-HYDROXYBUTANOIC ACID

(S)-Homeserine

HOMOSERINE, (S)-2-AMINO-4-HYDROXYBUTYRIC ACID

L-Homoserine, (S)-2-Amino-4-hydroxybutyric acid

H-HOSER-OHCL

L-Beta-Homo-Ser

(2S)-2-Amino-4-hydroxybutanoic acid

H-HoSer-OHCl;H-HoSer-OHCl

L-Homoserine,97%

(S)-2-Amino-4-hydroxybutyric acid Hse

L-Homoserine 98%

(S)-2-Amino-4-hydroxybutyric acid Hse H-HoSer-OH

H-Hser-OH ,98%

L-Homoserine

NSC 206251

L-(-)-HOMOSERINE FOR SYNTHESIS

L-HoMoserine, 95+%

HSD17B6

RODH

SDR9C6

L-Homoserine, >=98%

L-Homoserine&gt

L-Homoserine USP/EP/BP

laevo-homoserine

(2S)-2-azaniumyl-4-hydroxybutanoate

L-Homoserine 672-15-1

L-Homoserine (9CI, ACI)

(2S)-2-amino-4-hydroxybutanoic acid (homoserine)

Lysine Impurity 12 (L-?Homoserine)

Carisoprodol Impurity 3 (Carisoprodol EP Impurity C)

LChemicalbook-2-AMINO-4-HYDROXYBUTYRICACID

672-15-1

6-00-6

627-15-1

HOCH2CH2CHNH2COOH

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Homo-Amino Acids

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Specialty Synthesis