L(+)-allo-Threonine

Product Name: L(+)-allo-Threonine
CAS No.: 28954-12-3
Chemical Name: L(+)-allo-Threonine
Synonyms: Allo-Thr-OH;H-ALLO-THR-O;H-ALLO-THR-OH;L-allo-Thr-OH;l-allothreonin;ALLO-THREONINE;H-L-ALLO-THR-OH;L-ALLO-THREONINE;allo-l-threonine;H-ALLO-THR(BUT)-OH
CBNumber: CB8691943
Molecular Formula: C4H9NO3
Formula Weight: 119.12
MOL File: 28954-12-3.mol

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L(+)-allo-Threonine Property

Melting point:: 272 °C (dec.)(lit.)
alpha: 9 º (c=2, H2O)
Boiling point:: 222.38°C (rough estimate)
Density: 1.3126 (rough estimate)
refractive index: 10 ° (C=5, H2O)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Water (Slightly)
pka: pK1: 2.108(+1);pK2: 9.096(0) (25°C)
form: Crystalline Powder
color: White to off-white
optical activity: [α]23/D +9.0°, c = 2 in H2O
BRN: 1721645
InChI: InChI=1S/C4H9NO3/c1-2(6)3(5)4(7)8/h2-3,6H,5H2,1H3,(H,7,8)/t2-,3-/m0/s1
InChIKey: AYFVYJQAPQTCCC-HRFVKAFMSA-N
SMILES: C(O)(=O)[C@H]([C@@H](O)C)N
CAS DataBase Reference: 28954-12-3(CAS DataBase Reference)

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Safety

Safety Statements: 24/25
WGK Germany: 3
RTECS: BA4055000
HS Code: 29225090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 210269
Product name: L-allo-Threonine
Purity: 99%
Packaging: 250MG
Price: $404
Updated: 2023/01/07

TCI Chemical

Product number: A1519
Product name: L-Allothreonine
Purity: >99.0%(HPLC)
Packaging: 1g
Price: $455
Updated: 2025/07/31

TCI Chemical

Product number: A1519
Product name: L-Allothreonine
Purity: >99.0%(HPLC)
Packaging: 100mg
Price: $125
Updated: 2025/07/31

TRC

Product number: A548535
Product name: L-allo-Threonine
Packaging: 10g
Price: $1240
Updated: 2021/12/16

Usbiological

Product number: 259922
Product name: L-Allothreonine
Packaging: 1g
Price: $508
Updated: 2021/12/16

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L(+)-allo-Threonine Chemical Properties,Usage,Production

Chemical Properties

white to off-white crystalline powder

Uses

L-allo-Threonine is a reactant used in the synthesis of an antibiotic, globomycin, and its congener, SF-1902 A5.

Definition

ChEBI: L-allothreonine is the L-enantiomer of allothreonine. It has a role as an Escherichia coli metabolite and a Saccharomyces cerevisiae metabolite. It is an allothreonine and a L-alpha-amino acid. It is an enantiomer of a D-allothreonine. It is a tautomer of a L-allothreonine zwitterion.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64420-00-4

72-19-5

The general procedure for the synthesis of L-threonine from 5-(1-hydroxyethyl)urea (CAS:64420-00-4) is as follows: in a 1 L autoclave, 144 g (1 mol) of 5-(1-hydroxyethyl)urea, 68 g of 25% ammonia, 110 g of calcium hydroxide (1.5 mol), 500 g of water, and 50 mL of n-butanol were added in sequence. The mixture was heated to 160-170°C and the reaction pressure was maintained at 1.5-2.0 MPa for 4 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the pH was adjusted by passing carbon dioxide to 8. The reaction mixture was filtered and the mother liquor was concentrated under reduced pressure. To the residue, 150 g of methanol was added and refluxed for 2 h. Crystals were precipitated after cooling. The crystals were collected by filtration, and the filter cake was dried under vacuum at 120°C for 4 h. 106.4 g of 2-amino-3-hydroxybutyric acid was obtained with a purity of 96% and a yield of 89.4%.

References

[1] Patent: CN104892521, 2018, B. Location in patent: Paragraph 0069; 0070

L(+)-allo-Threonine Preparation Products And Raw materials

Raw materials

Preparation Products

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L(+)-allo-Threonine Suppliers

Americas 1 Belgium 1 Canada 1 China 226 Europe 1 Germany 4 India 3 Japan 5 South Korea 1 Switzerland 1 United Kingdom 8 United States 34 Global 286

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View Lastest Price from L(+)-allo-Threonine manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: L-Allothreonine 28954-12-3
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 1000kg
Release date: 2021-08-28

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-L-allo-Thr-OH 28954-12-3
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1T
Release date: 2023-09-25

Hebei Chuanghai Biotechnology Co., Ltd

Product: L(+)-allo-Threonine 28954-12-3
Price: US $30.00-10.00/KG
Min. Order: 50KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-05

28954-12-3, L(+)-allo-ThreonineRelated Search:

4-Aminobutyric acid ALTRENOGEST L-Threonine DL-4-Amino-3-hydroxybutyric acid 3-Hydroxybutyric acid Glycine L-Alanine H-PHG-OME HCL (S)-(+)-2-Amino-3-hydroxy-3-methylbutanoic acid POLYOXIN B (2S,3S)-2-Amino-3-methoxybutanoic acid TRANS-3-HYDROXY-L-PROLINE MYRIOCIN (2S,3S)-(2S,3R)-2-AMINO-3-HYDROXY-4-METHYLPENTANOIC ACID (2R,3R)-(-)-ALLO-THREONINE,D(-)-ALLO-THREONINE,D-ALLO-THREONINE DL-ALLO-THREONINE FMOC-ALLO-THR(TBU)-OH H-ALLO-THR(TBU)-OH,ALLO-THREONINE(TBU)-OH,O-T-BUTYL-L-ALLO-THREONINE

l-allothreonin

O-T-BUTYL-L-ALLO-THREONINE

H-ALLO-THR(BUT)-OH

H-ALLO-THR-O

H-ALLO-THR-OH

H-ALLO-THR(TBU)-OH

H-L-ALLO-THR-OH

L(+)-ALLO-THREONINE

L-ALLO-THREONINE

(2S 3S)-(+)-2-AMINO-3-HYDROXYBUTYRIC ACID

(2S,3S)-2-AMINO-3-HYDROXYBUTYRIC ACID

(2S,3S)-(+)-ALLO-THREONINE

ALLO-THREONINE(TBU)-OH

ALLO-THREONINE

H-allo-Thr-OH(L-Allo-Threonine)

Allo-Thr-OH

(2S 3S)-(+)-2-AMINO-3-HYDROXYBUTYRIC ACID 99%

H-L-allo-Thr(tBu)-OH

O-t-Butyl-allo-L-threonine

(2S,3S)-3-Hydroxy-2-aminobutanoic acid

L(+)-allo-Threonine,99%

(2S,3S)-2-Amino-3-hydroxybutyric acid, H-L-allo-Thr-OH

L-allo-Thr-OH

allo-l-threonine

L(+)-allo-Threonine/C4H9NO3

L-Allothreonine&gt

L(+)-allo-Threonine USP/EP/BP

L-Allothreonine (9CI, ACI)

<sc>L</sc>-<i>allo</i>-Threonine

L-allo-Threonine 98~102%

28954-12-3

Unnatural Amino Acid Derivatives

Threonine Derivatives

Specialty Synthesis

Peptide Synthesis

amino acid derivative

Threonine [Thr, T]

Amino Acids