Dimethyl L-aspartate hydrochloride
- Product Name
- Dimethyl L-aspartate hydrochloride
- CAS No.
- 32213-95-9
- Chemical Name
- Dimethyl L-aspartate hydrochloride
- Synonyms
- L-ASPARTIC ACID DIMETHYL ESTER HCL;Dimethyl L;H-Asp(OMe)-OMe;H-ASP(OME)-OME HCL;L-Asp(Ome)-Ome·HCl;H-L-ASP(ME)-OME HCL;L-Aspartic acid di;Asparagine Impurity 22;Dimethyl L-Aspartate HCl;ASPARTIC ACID(OME)-OME HCL
- CBNumber
- CB3700615
- Molecular Formula
- C6H12ClNO4
- Formula Weight
- 197.62
- MOL File
- 32213-95-9.mol
Dimethyl L-aspartate hydrochloride Property
- Melting point:
- 115-117 °C(lit.)
- alpha
- 15 º (c=1, MeOH)
- refractive index
- 12 ° (C=1.4, H2O)
- storage temp.
- Inert atmosphere,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly), Water (Slightly)
- form
- Powder
- color
- White to Off-white
- Water Solubility
- Soluble in water (almost transparency) and methanol.
- InChI
- InChI=1/C6H11NO4.ClH/c1-10-5(8)3-4(7)6(9)11-2;/h4H,3,7H2,1-2H3;1H/t4-;/s3
- InChIKey
- PNLXWGDXZOYUKB-WCCKRBBISA-N
- SMILES
- [C@@H](N)(C(=O)OC)CC(=O)OC.Cl |&1:0,r|
- CAS DataBase Reference
- 32213-95-9(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 456233
- Product name
- L-Aspartic acid dimethyl ester hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $91.6
- Updated
- 2023/01/07
- Product number
- 456233
- Product name
- L-Aspartic acid dimethyl ester hydrochloride
- Purity
- 97%
- Packaging
- 25g
- Price
- $161
- Updated
- 2023/01/07
- Product number
- A1506
- Product name
- Dimethyl L-Aspartate Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 5g
- Price
- $47
- Updated
- 2025/07/31
- Product number
- A1506
- Product name
- Dimethyl L-Aspartate Hydrochloride
- Purity
- >98.0%(N)(T)
- Packaging
- 25g
- Price
- $186
- Updated
- 2025/07/31
- Product number
- D462345
- Product name
- Dimethyl L-Aspartate Hydrochloride
- Packaging
- 5g
- Price
- $80
- Updated
- 2021/12/16
Dimethyl L-aspartate hydrochloride Chemical Properties,Usage,Production
Chemical Properties
white to off-white crystalline powder
Uses
Dimethyl L-Aspartate Hydrochloride was used in the synthesis of enzyme and pH dual responsive L-amino acid based biodegradable polymer nanocarrier that can be used for multidrug delivery to cancer cells.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
67-56-1
56-84-8
32213-95-9
Example 1; This example demonstrates the synthesis of dimethyl (S)-2-aminosuccinate hydrochloride from L-aspartic acid. The steps were as follows: a solution of L-aspartic acid (13.5 g, 100 mmol) dissolved in 100 ml of methanol was slowly added dropwise to pure thionyl chloride, and the reaction mixture was stirred continuously for 48 hours at room temperature. After completion of the reaction, the reaction mixture was concentrated in vacuum using a rotary evaporator. Subsequently, it was extracted and washed by adding methanol (3 x 30 ml) and dichloromethane (3 x 30 ml) to finally obtain L-aspartic acid dimethyl ester hydrochloride (19.5 g, quantitative yield) in white powder form.
References
[1] Organic and Biomolecular Chemistry, 2009, vol. 7, # 20, p. 4309 - 4316
[2] Patent: US2007/142467, 2007, A1. Location in patent: Page/Page column 5
[3] Chemical Communications, 2011, vol. 47, # 23, p. 6569 - 6571
[4] Journal of Medicinal Chemistry, 2012, vol. 55, # 23, p. 10460 - 10474
[5] Organic and Biomolecular Chemistry, 2015, vol. 13, # 15, p. 4514 - 4523
Dimethyl L-aspartate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Dimethyl L-aspartate hydrochloride manufacturers
- Product
- L-Asp(OMe)-OMeHCl 32213-95-9
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-12
- Product
- Dimethyl L-aspartate hydrochloride 32213-95-9
- Price
- US $0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-31
- Product
- Dimethyl L-aspartate hydrochloride 32213-95-9
- Price
- US $30.00-12.00/kg
- Min. Order
- 1kg
- Purity
- 0.99
- Supply Ability
- 20 tons
- Release date
- 2023-11-01