beta-Methyl L-aspartate hydrochloride
- Product Name
- beta-Methyl L-aspartate hydrochloride
- CAS No.
- 16856-13-6
- Chemical Name
- beta-Methyl L-aspartate hydrochloride
- Synonyms
- L-Aspartic;(S)-2-amino-4-methoxy-4-oxobutanoic acid;(S)-2-AMino-4-Methoxy-4-oxobutanoic acid hydrochloride;H-ASP(OME).HCL;L-Asp(Ome).HCL;H-Asp(OMe)-OHCl;H-L-Asp(Ome).HCL;H-ASP(OME)-OH·HCL;H-ASP(OME)-OH HCL;L-Asp(OMe)-OH·HCl
- CBNumber
- CB8267036
- Molecular Formula
- C5H10ClNO4-
- Formula Weight
- 183.59
- MOL File
- 16856-13-6.mol
beta-Methyl L-aspartate hydrochloride Property
- Melting point:
- 191-193°C
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
- form
- Solid
- color
- White to Almost white
- CAS DataBase Reference
- 16856-13-6(CAS DataBase Reference)
Safety
- Safety Statements
- 24/25
- WGK Germany
- 3
- HS Code
- 29224999
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M2024
- Product name
- 4-Methyl L-Aspartate Hydrochloride
- Purity
- >95.0%(T)
- Packaging
- 5g
- Price
- $40
- Updated
- 2025/07/31
- Product number
- M2024
- Product name
- 4-Methyl L-Aspartate Hydrochloride
- Purity
- >95.0%(T)
- Packaging
- 25g
- Price
- $120
- Updated
- 2025/07/31
- Product number
- 259972
- Product name
- L-Aspartic acid b-methyl ester hydrochloride
- Packaging
- 25g
- Price
- $322
- Updated
- 2021/12/16
- Product number
- A788935
- Product name
- L-AsparticAcid4-MethylEsterHydrochloride
- Packaging
- 5g
- Price
- $120
- Updated
- 2021/12/16
- Product number
- CS-0019407
- Product name
- β-MethylL-aspartatehydrochloride
- Purity
- >97.0%
- Packaging
- 500g
- Price
- $120
- Updated
- 2021/12/16
beta-Methyl L-aspartate hydrochloride Chemical Properties,Usage,Production
Chemical Properties
White crystalline powder
Uses
L-Aspartic acid 4-methyl ester is a protected form of L-Aspartic acid. L-Aspartic acid is a nonessential amino acid that is used to biosynthesize other amino acids within the human body. L-Aspartic acid also increases membrane conductance of mammalian neurons by voltage-dependent means, causing depolarization and nerve impulses that travel to key areas of the central nervous system.
Synthesis
67-56-1
56-84-8
16856-13-6
At -10°C, 5 g of L-aspartic acid (37.6 mmol) was slowly added to 26 mL of anhydrous methanol solution containing 3.8 mL (41.2 mmol) of SOCl? The reaction mixture was stirred continuously at room temperature for 2 h. Subsequently, 75 mL of diethyl ether was added to promote precipitation of the product. The resulting white solid was collected by filtration and washed with 2 x 50 mL of diethyl ether to give the final (S)-aspartic acid-β-methyl ester hydrochloride in 85% yield. The product was a white solid.1H NMR (300 MHz, DMSO) characterized the data as follows: δ (ppm) = 3.05 (dd, J = 3.4,4.7 Hz, 2H, CH?), 3.78 (s, 3H, OCH?), 4.31-4.35 (m, 1H, CHN).
Purification Methods
Recrystallise it from MeOH by adding anhydrous Et2O [Bach et al. Biochemical Preparations 13 20 1971].
References
[1] Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1989, p. 833 - 834
[2] Journal of Organic Chemistry, 1988, vol. 53, # 9, p. 1900 - 1903
[3] Patent: WO2013/30193, 2013, A1. Location in patent: Paragraph 30
[4] Journal of Organic Chemistry, 1985, vol. 50, # 24, p. 4982 - 4984
[5] Chemical Communications, 2001, # 18, p. 1710 - 1711
beta-Methyl L-aspartate hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from beta-Methyl L-aspartate hydrochloride manufacturers
- Product
- H-L-Asp(Ome).HCL 16856-13-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-22
- Product
- beta-Methyl L-aspartate hydrochloride 16856-13-6
- Price
- US $1.10/g
- Min. Order
- 1g
- Purity
- 99.0% min
- Supply Ability
- 100 tons min
- Release date
- 2021-05-25
- Product
- beta-Methyl L-aspartate hydrochloride 16856-13-6
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-11