Glycine methyl ester hydrochloride
- Product Name
- Glycine methyl ester hydrochloride
- CAS No.
- 5680-79-5
- Chemical Name
- Glycine methyl ester hydrochloride
- Synonyms
- METHYL GLYCINATE HYDROCHLORIDE;GLYCINE METHYL ESTER HCL;METHYL GLYCINATE HCL;AMINOACETIC ACID METHYL ESTER HYDROCHLORIDE;MURA-005;Gly-OmeHCl;ycine MethyL;H-Gly-OMe.HCI;JACS-5680-79-5;GLYCINE-OME HCL
- CBNumber
- CB6713993
- Molecular Formula
- C3H8ClNO2
- Formula Weight
- 125.55
- MOL File
- 5680-79-5.mol
Glycine methyl ester hydrochloride Property
- Melting point:
- 175 °C (dec.)(lit.)
- Density
- 1.000
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- >1000 g/L (20°C)
- form
- Powder or Cyrstals
- color
- White
- Water Solubility
- >1000 g/L (20 ºC)
- Sensitive
- Hygroscopic
- BRN
- 3593644
- Stability:
- Stable. Incompatible with strong oxidizing agents.
- InChI
- InChI=1S/C3H7NO2.ClH/c1-6-3(5)2-4;/h2,4H2,1H3;1H
- InChIKey
- COQRGFWWJBEXRC-UHFFFAOYSA-N
- SMILES
- C(=O)(OC)CN.Cl
- CAS DataBase Reference
- 5680-79-5(CAS DataBase Reference)
Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
- HS Code
- 29224995
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- G6600
- Product name
- Glycine methyl ester hydrochloride
- Purity
- 99%
- Packaging
- 5g
- Price
- $51.9
- Updated
- 2025/07/31
- Product number
- G6600
- Product name
- Glycine methyl ester hydrochloride
- Purity
- 99%
- Packaging
- 100g
- Price
- $63.9
- Updated
- 2025/07/31
- Product number
- G0246
- Product name
- Glycine Methyl Ester Hydrochloride
- Purity
- >97.0%(HPLC)(N)
- Packaging
- 25g
- Price
- $24
- Updated
- 2025/07/31
- Product number
- G0246
- Product name
- Glycine Methyl Ester Hydrochloride
- Purity
- >97.0%(HPLC)(N)
- Packaging
- 500g
- Price
- $100
- Updated
- 2025/07/31
- Product number
- G6600
- Product name
- Glycine methyl ester hydrochloride
- Purity
- 99%
- Packaging
- 500g
- Price
- $124
- Updated
- 2025/07/31
Glycine methyl ester hydrochloride Chemical Properties,Usage,Production
Chemical Properties
Crystalline
Uses
Glycine methyl ester hydrochloride a non-essential amino acid used for human development.
Uses
A Glycine ester, a non-essential amino acid for human development.
reaction suitability
reaction type: solution phase peptide synthesis
Synthesis
67-56-1
56-40-6
5680-79-5
(2) Preparation of glycine methyl ester hydrochloride: 60 mL of methanol was added to a 100 mL round-bottomed flask under ice-bath conditions, followed by the slow dropwise addition of 4 mL of sulfoxide chloride (SOCl2) through a constant-pressure dropping funnel (with a drying tube on top). The resulting off-gas was absorbed using NaOH solution. After stirring the reaction mixture for 1 h, 8 mmol of glycine was added and stirring was continued for 30 min at room temperature. Subsequently, the reaction system was warmed up to 66 °C and refluxed for 6 hours. The progress of the reaction was monitored by thin layer chromatography (TLC) using 2% ninhydrin ethanol solution as a color developer until the disappearance of the raw material spot. After completion of the reaction, the solvent was removed by evaporation to give glycine methyl ester hydrochloride in 100% yield.
Purification Methods
Crystallise the ester salt from MeOH. [Werbin & Spoerri J Am Chem Soc 69 1682 1947, Beilstein 4 H 340, 4 III 1116.]
References
[1] Synthetic Communications, 1998, vol. 28, # 3, p. 471 - 474
[2] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788,15
[3] European Journal of Organic Chemistry, 2012, # 29, p. 5774 - 5788
[4] Patent: US2014/206741, 2014, A1. Location in patent: Paragraph 0131
[5] European Journal of Organic Chemistry, 2017, vol. 2017, # 3, p. 695 - 703
Glycine methyl ester hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Glycine methyl ester hydrochloride manufacturers
- Product
- H-Gly-Ome.HCl 5680-79-5
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-03-29
- Product
- Glycine methyl ester hydrochloride 5680-79-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-11-01
- Product
- Glycine methyl ester hydrochloride 5680-79-5
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 98%
- Supply Ability
- 1ton
- Release date
- 2022-09-23