Glycine ethyl ester hydrochloride

Product Name: Glycine ethyl ester hydrochloride
CAS No.: 623-33-6
Chemical Name: Glycine ethyl ester hydrochloride
Synonyms: ETHYL GLYCINATE HYDROCHLORIDE;GLYCINE ETHYL ESTER;GLYCINE ETHYL ESTER HCL;GEE;H-GLY-OET HCL;ETHYL AMINOACETATE HYDROCHLORIDE;usafdo-10;ycine EthyL;Gly-OEt HCl;GLYCINE-OET HCL
CBNumber: CB5275670
Molecular Formula: C4H9NO2.ClH
Formula Weight: 139.58
MOL File: 623-33-6.mol

More

Less

Glycine ethyl ester hydrochloride Property

Melting point:: 145-146 °C(lit.)
Density: 1.371 g/cm3
storage temp.: 2-8°C
solubility: >1000 g/L (20 °C)
form: Crystalline Powder
pka: pK1:7.66(＋1) (25°C)
color: White
Odor: Odorless
PH: 2.9 (10g/l, H2O, 20℃)
Water Solubility: >1000 g/L (20 ºC)
Sensitive: Hygroscopic
BRN: 3594034
InChIKey: TXTWXQXDMWILOF-UHFFFAOYSA-N
CAS DataBase Reference: 623-33-6(CAS DataBase Reference)
EPA Substance Registry System: Glycine, ethyl ester, hydrochloride (623-33-6)

More

Less

Safety

Hazard Codes: Xi
Risk Statements: 41-36/37/38
Safety Statements: 26-39-24/25-37/39
WGK Germany: 3
RTECS: MC0525000
TSCA: Yes
HS Code: 29224995

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H318Causes serious eye damage

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G6503
Product name: Glycine ethyl ester hydrochloride
Purity: 99%
Packaging: 5G
Price: $35.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: G6503
Product name: Glycine ethyl ester hydrochloride
Purity: 99%
Packaging: 100g
Price: $65.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: G6503
Product name: Glycine ethyl ester hydrochloride
Purity: 99%
Packaging: 500g
Price: $97.7
Updated: 2024/03/01

TCI Chemical

Product number: G0102
Product name: Glycine Ethyl Ester Hydrochloride
Purity: >99.0%(T)
Packaging: 25g
Price: $19
Updated: 2024/03/01

TCI Chemical

Product number: G0102
Product name: Glycine Ethyl Ester Hydrochloride
Purity: >99.0%(T)
Packaging: 500g
Price: $75
Updated: 2024/03/01

More

Less

Glycine ethyl ester hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Uses

Glycine ethyl ester (GEE) is used in conjunction with N-(3-Dimethylaminopropyl)-N?-ethylcarbodiimide (EDC) for carboxyl-foot printing studies of proteins. The GEE/EDC protocol effects specific derivatization of glutamate and aspartate carboxyl side chains on intact proteins. This reaction is readily done under aqueous conditions at physiological pH. It is mainly used as a pharmaceutical raw material. Glycine ethyl ester hydrochloride is an important intermediate for preparing chrysanthemic acid or two chlorine chrysanthemic acid and is mainly used in the synthesis of anti-inflammatory drugs, but also can be used for the synthesis of four imidazole acetic acid.

Uses

As a Glycine (G615990) ester, Glycine ethyl ester hydrochloride can be used as parakeratosis inhibitor and external composition for skin.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

A production method for glycine ethyl ester hydrochloride:First add dehydrated ethanol in 1# reactor, pass into anhydrous hydrogen chloride to obtain hydrochloric acid-ethanol solution; Add a certain amount of triethyl orthoformate and glycine and hydrochloric acid-ethanol solution in 2# reactor, in the Reaction under action; after the reaction is complete, distill and recover ethanol and ethyl formate; then add alcohol-ether mixture, wash, filter, concentrate, recrystallize, and vacuum dry to obtain ethyl glycine hydrochloride.

Purification Methods

Crystallise it from absolute EtOH or EtOH/Et2O. [Marvel Org Synth Coll Vol II 310 1943, Beilstein 4 II 780, 4 III 3 75.]

Glycine ethyl ester hydrochloride Preparation Products And Raw materials

Raw materials

Hydrogen chloride ethanol solution Ethanol Hydrochloric acid alcohol Glycine weak Hydrochloric acid Hydrogen Hexamethylenetetramine

Preparation Products

1-(Boc-amino)cyclopropanecarboxylic acid N-Boc-3-cyano-4-hydroxypyrrolidine ethyl 2-(3-bromo-2-oxopyrazin-1(2H)-yl)acetate ETHYL 2-[(2-THIENYLCARBONYL)AMINO]ACETATE 2,2-Dimethyl-3-(2-methylpropyl)cyclopropanecarboxylic acid p-(methoxymethyl)benzyl ester tert-butyl 3-(aminomethyl)-4-hydroxypyrrolidine-1-carboxylate Ethyl N-(diphenylmethylene)glycinate Ethyl imidazole-4-carboxylate ethyl 2-(3,4-dihydro-2,3-dioxopyrazin-1(2H)-yl)acetate N-(ETHOXYCARBONYL)-N-(ETHOXYCARBONYKLETHYL)GLYCINE ETHYL ESTER H-GLY-AMC HBR 1-Aminocyclopropanecarboxylic acid Glycine methyl ester hydrochloride N-FORMYLGLYCINE ETHYL ESTER 3-BROMO-6-METHYL-2-OXO-1(2H)-PYRAZINEACETIC ACID ETHYL ESTER Anagrelide ethyl 2-(3,4-dihydro-6-methyl-2,3-dioxopyrazin-1(2H)-yl)acetate Ethyl diazoacetate 4-Imidazolemethanol hydrochloride Tetramethrin 4-BOC-AMINOMETHYL-1-N-BOC-PYRROLIDIN-3-OL 4,5,6,7-TETRAHYDRO-2-METHYLFURO[2,3-C]PYRIDINE

More

Less

Glycine ethyl ester hydrochloride Suppliers

Americas 1 Austria 1 Belgium 3 Canada 1 China 591 Europe 5 France 1 Germany 13 Hungary 1 India 66 Japan 8 Poland 1 Slovakia 1 South Korea 1 Switzerland 6 United Kingdom 15 United States 60 Global 775

kaichuang

Tel: 0513-18051647519 18051647519
Email: 815605858@qq.com
Country: China
ProdList: 12
Advantage: 58

Shandong Vantage Specialty Chemicals Biotechnology Co., Ltd.

Tel: 133-96369453 18678026865
Fax: 0536-2101172
Email: sdfantai@163.com
Country: China
ProdList: 867
Advantage: 58

Mountainous Chemical Co.,Ltd

Tel: 0523-87306168 18352621837
Fax: +86-523-87306528
Email: sales@mountainouschem.com
Country: China
ProdList: 15
Advantage: 58

Jinan Wald Chemical Co., Ltd.

Tel: 0531-88773586 13210588999
Fax: 053188773586
Email: 304264064@qq.com
Country: China
ProdList: 192
Advantage: 58

Yangzhou modier Electronic Materials Co., Ltd

Tel: 0514-82098883; 13761402923
Email: market@modeltemol.com
Country: China
ProdList: 923
Advantage: 58

Hebei Mojin Biotechnology Co.,Ltd

Tel: 0311-15028179902 15028179902
Fax: 18503279000
Email: bella@hbmojin.com
Country: China
ProdList: 111
Advantage: 58

Shandong Debek Bioengineering Co. LTD

Tel: 13854830608; 13854830608
Email: 13854830608@163.com
Country: China
ProdList: 1514
Advantage: 58

SUZHOU YINGKE BIOTECHNOLOGY CO.,LTD.

Tel: 0512-62896201 13806138270
Email: sales@szykbio.com
Country: China
ProdList: 18
Advantage: 58

Beijing Leaderherb Bio-Tech. Co., LTD.

Tel: 010-51288246
Email: 300abc@sina.com
Country: China
ProdList: 72
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

More

Less

View Lastest Price from Glycine ethyl ester hydrochloride manufacturers

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Glycine ethyl ester hydrochloride 623-33-6
Price: US $79.00-38.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-12-24

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-Gly-Oet.HCl 623-33-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-27

Hebei Weibang Biotechnology Co., Ltd

Product: Glycine ethyl ester hydrochloride 623-33-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-29

623-33-6, Glycine ethyl ester hydrochlorideRelated Search:

Trinexapac-ethyl Topotecan hydrochloride Glycine methyl ester hydrochloride Ethyl L-phenylalaninate hydrochloride Glycine Ethylparaben Ethanol Ethyl acetate Ethyl nipecotate 4-Aminophenylacetic acid Creatine ethyl ester hydrochloride L-Cysteine ethyl ester hydrochloride ISOXADIFEN-ETHYL 7-Amino-heptanoic acid ethyl ester hydrochloride Ethyl cyanoacetate 4-Hydroxy-D-(-)-2-phenylglycine L-Arginine ethyl ester dihydrochloride Ethyl acrylate

Glycineethylesterhydrochlor

Glycocollethylesterhydrochloride

usafdo-10

glycine ethyhydnchlordeester

Glycineethylester·HCl,Glycineethylesterhydrochloride

Ethyl 2-aminoacetate, hydrochloride

Glycine ethyl ester hydrochloride ,98%

2-Aminoacetic acid ethyl·hydrochloride

Aminoacetic acid ethyl·hydrochloric acid

Glycine ethyl·hydrochloride

(2-Ethoxy-2-oxoethyl)aMMoniuM Chloride

Glycine Ethyl Ester Monohydrochloride

Glycine Hydrochloride Ethyl Ester

ETHYL GLYCINATE HYDROCHLORIDE FOR SYNTHE

Glycine ethyl ester HC1

Glycine ethyl ester hydrochloride, 99% 100GR

Glycine ethyl ester hydrochloride, 99% 500GR

Glycine ethylester HCI

ycine EthyL

RARECHEM AL BW 0032

H-GLY-OET HCL

GLYCINE ETHYL ESTER

GLYCINE ETHYL ESTER HCL

GLYCINE ETHYL ESTER HYDROCHLORIDE

GLYCINE-OET HCL

ETHYL AMINOACETATE HCL

ETHYL AMINOACETATE HYDROCHLORIDE

ETHYL GLYCINATE HYDROCHLORIDE

AMINO-ACETIC ACID ETHYL ESTER

AMINOACETIC ACID ETHYL ESTER HYDROCHLORIDE

Ethyl glycinate hydrochloride~H-Gly-OEt.HCl

Ethyl Glycinate, HCl (1.00893)

Glycine ethyl ester hydrochloride 99%

Gly-OEt HCl

Glycineethylesterhydrochloride,99%

GEE

GlyClne ethyl ester HCl

Ethyl glycinate hydrochloride for synthesis

Glycine ethyl ether hydrochloride

GLYCINE ETHYL ESTER .HCl (623-33-6)

GlycineEthylEsterHydrochloride&gt

Ethylglycinathydrochlorid

Glycine Impurity 10

glycine ethyl ester hydrochloric acid

Ethyl glycine hydrochloride

Glycine ethyl ester hydrochloride USP/EP/BP

Glycine ethyl ester hydrochloride25

GLYCINE ETHYL ESTER HYDROCHLORIDE For Synthesis

Glycine hexanoate hydrochloride

Ethyl glycerate hydrochloride

Glycine Ethyl Ester Hydrochloride (Ethyl Glycinate Hydrochloride)

Glycine ethylester hydrochloride - Assay 99%

Glycine Ethylester Hydrochloride 99% For Synthesis

623-33-6

C4H9NO2HClC4H10ClNO2

C4H9NO2xHCl

CH3CH2O2CCH2NH2HCl

NH2CH2COOC2H5HCl