Ethyl L-phenylalaninate hydrochloride

Product Name: Ethyl L-phenylalaninate hydrochloride
CAS No.: 3182-93-2
Chemical Name: Ethyl L-phenylalaninate hydrochloride
Synonyms: ETHYL 2-AMINO-3-PHENYLPROPANOATE HYDROCHLORIDE;Phe-OEt HCl;L-Phe-OEt.HCL;H-PHE-OET HCL;H-L-Phe-OEt*HCl;Ethyl L-phenylalanin;PHENYLALANINE-OET HCL;L-phenylalanine ethylester;L-PHANYLALANINEETHYLESTERHCL;L-PhenylalanineEthylEster>99%
CBNumber: CB0776127
Molecular Formula: C11H16ClNO2
Formula Weight: 229.7
MOL File: 3182-93-2.mol

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Ethyl L-phenylalaninate hydrochloride Property

Melting point:: 155-156 °C(lit.)
alpha: 33.7 º (c=2, C2H5OH 21 ºC)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Methanol, Water
form: Fine Needle-Like Crystalline Solid
color: White
optical activity: [α]20/D 7.8°, c = 2 in H2O
Water Solubility: Soluble in methanol and water.
Sensitive: Hygroscopic
BRN: 3657823
InChI: InChI=1/C11H15NO2.ClH/c1-2-14-11(13)10(12)8-9-6-4-3-5-7-9;/h3-7,10H,2,8,12H2,1H3;1H/t10-;/s3
InChIKey: FPFQPLFYTKMCHN-MEQOOBBNNA-N
SMILES: C1(C=CC=CC=1)C[C@H](N)C(=O)OCC.Cl |&1:7,r|
CAS DataBase Reference: 3182-93-2(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 22-24/25-26
WGK Germany: 3
HS Code: 29224995

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 220701
Product name: L-Phenylalanine ethyl ester hydrochloride
Purity: 99%
Packaging: 10g
Price: $61.6
Updated: 2025/07/31

Sigma-Aldrich

Product number: 220701
Product name: L-Phenylalanine ethyl ester hydrochloride
Purity: 99%
Packaging: 50g
Price: $287.7
Updated: 2025/07/31

TCI Chemical

Product number: P1949
Product name: Ethyl L-Phenylalaninate Hydrochloride
Packaging: 5G
Price: $43
Updated: 2025/07/31

TCI Chemical

Product number: P1949
Product name: Ethyl L-Phenylalaninate Hydrochloride
Packaging: 25G
Price: $86
Updated: 2025/07/31

Usbiological

Product number: 164695
Product name: L-Phenylalanine Ethyl Ester Hydrochloride
Packaging: 1g
Price: $319
Updated: 2021/12/16

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Ethyl L-phenylalaninate hydrochloride Chemical Properties,Usage,Production

Chemical Properties

Crystalline

Uses

L-Phenylalanine Ethyl Ester Hydrochloride is an derivative of L-Phenylalanine (P319415), an essential amino acid.

reaction suitability

reaction type: solution phase peptide synthesis

Synthesis

64-17-5

63-91-2

3182-93-2

1. L-phenylalanine (5 g, 30 mmol) was dissolved in anhydrous ethanol (30 mL). 2. slowly add trimethylchlorosilane (TMSCl, 6.915 mL, 54 mmol) to the reaction system at room temperature. 3. A reflux condenser was assembled and the reaction system was heated in an oil bath at 80 °C. 4. 4. The reaction mixture was allowed to react overnight under stirring conditions. 5. On the following day, the reaction system was cooled to room temperature and the reaction solution was subsequently concentrated under reduced pressure. 6. 6. The concentrated residue was dissolved in ether (Et2O). 7. The resulting slurry was filtered and the separated solid product was further washed with ether. 8. The washed solid was dried under high vacuum to afford the target product (S)-ethyl 2-amino-3-phenylpropionate hydrochloride (6.86 g, 99% yield). 9. The structure of the product was confirmed by 1H NPD analysis. 9. The structure of the product was confirmed by 1H NMR (400 MHz, DMSO-d6): δ8.52 (s, 3H), 7.30 (m, 5H), 4.24 (ABX, JAX=7.8 Hz, JBX=6.2 Hz, 1H), 4.11 (m, 2H), 3.17, 3.05 (ABX, JAB=-14 Hz, JBX=5.8 Hz, JAX=7.6 Hz, 2H), 1.09 (t, J=6.8 Hz, 3H).

References

[1] Patent: US2017/71964, 2017, A1. Location in patent: Paragraph 0594-0595
[2] Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006, vol. 45, # 8, p. 1942 - 1944
[3] Tetrahedron Letters, 2015, vol. 56, # 49, p. 6900 - 6903
[4] Chemical Communications, 2011, vol. 47, # 42, p. 11784 - 11786
[5] Recueil des Travaux Chimiques des Pays-Bas, 1990, vol. 109, # 7/8, p. 413 - 418

Ethyl L-phenylalaninate hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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Ethyl L-phenylalaninate hydrochloride Suppliers

Austria 1 Belgium 2 China 255 Europe 3 Germany 6 India 8 Japan 7 Russia 1 South Korea 1 Switzerland 2 United Kingdom 10 United States 41 Global 337

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View Lastest Price from Ethyl L-phenylalaninate hydrochloride manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: H-L-Phe-OEt.HCl 3182-93-2
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-03-22

Shaanxi Dideu Medichem Co. Ltd

Product: Ethyl L-phenylalaninate hydrochloride 3182-93-2
Price: US $1.00/Kg
Min. Order: 1Kg
Purity: 98%
Supply Ability: 20T
Release date: 2024-07-08

Zhuozhou Wenxi import and Export Co., Ltd

Product: Ethyl L-phenylalaninate hydrochloride 3182-93-2
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-07-10

3182-93-2, Ethyl L-phenylalaninate hydrochlorideRelated Search:

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PHENYLALANINE-OET HCL

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ethyl L-phenylalaninate hydrochloride

Phe-OEt HCl

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L-PHANYLALANINEETHYLESTERHCL

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(S)-Ethyl 2-aMino-3-phenylpropanoate hydrochloride

L-Phe-OEt.HCL

Ethyl L-phenylalanin

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Ethyl L-Phenylalaninate Hydrochloride,99%e.e.

L-PHENYLALANINE ETHYL ESTER HCL

L-(+)-PHENYLALANINE ETHYL ESTER HYDROCHLORIDE

L-PHENYLALANINE ETHYL ESTER HYDROCHLORIDE

ETHYL 2-AMINO-3-PHENYLPROPANOATE HYDROCHLORIDE

L-ETHYL PHENYLALANATE HYDROCHLORIDE

H-PHE-OET HCL

L-Phenylalanine ethyl ester hydrochloride, 98.5%

Ethyl L-phenylalaninate hydrochloride USP/EP/BP

<sc>L</sc>-Phenylalanine ethyl ester hydrochloride

3182-93-2

C6H5CH2CHNH2CO2C2H5

C11H16O2NCL

C6H5CH2CHNH2COOC2H5HCl

AMINE

Specialty Synthesis

Peptide Synthesis

Phenylalanine

Amino Acid Derivatives

Phenylalanine [Phe, F]

Amino hydrochloride

Amino Acid Derivatives

Peptide Synthesis

Phenylalanine

Amino Acids

Other enzyme inhibitors and activators

Other Enzyme Inhibitors and Activators.