4-(Diethylamino)salicylaldehyde
- Product Name
- 4-(Diethylamino)salicylaldehyde
- CAS No.
- 17754-90-4
- Chemical Name
- 4-(Diethylamino)salicylaldehyde
- Synonyms
- 4-(diethylamino)salicyladehyde;4-Diethylamino-2-hydroxybenzaldehyde;-6-;4(3H;6+3);amino)saL;5]thieno[2;8-tetrahydro-2;4-d]pyriMidine-2;Methyl 4-aMino-4
- CBNumber
- CB3499007
- Molecular Formula
- C11H15NO2
- Formula Weight
- 193.24
- MOL File
- 17754-90-4.mol
4-(Diethylamino)salicylaldehyde Property
- Melting point:
- 60-62 °C (lit.)
- Boiling point:
- 329.46°C (rough estimate)
- Density
- 1.0945 (rough estimate)
- refractive index
- 1.5041 (estimate)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 8.29±0.10(Predicted)
- form
- Powder or Crystalline Powder
- color
- Pale brown to pink to purple
- Water Solubility
- Insoluble in water.
- Sensitive
- Air Sensitive
- BRN
- 2212234
- InChIKey
- XFVZSRRZZNLWBW-UHFFFAOYSA-N
- CAS DataBase Reference
- 17754-90-4(CAS DataBase Reference)
- EPA Substance Registry System
- Benzaldehyde, 4-(diethylamino)-2-hydroxy- (17754-90-4)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 225681
- Product name
- 4-(Diethylamino)salicylaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $50.4
- Updated
- 2025/07/31
- Product number
- 225681
- Product name
- 4-(Diethylamino)salicylaldehyde
- Purity
- 98%
- Packaging
- 25g
- Price
- $77.1
- Updated
- 2025/07/31
- Product number
- D1752
- Product name
- 4-(Diethylamino)salicylaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 25g
- Price
- $32
- Updated
- 2025/07/31
- Product number
- D1752
- Product name
- 4-(Diethylamino)salicylaldehyde
- Purity
- >98.0%(GC)(T)
- Packaging
- 250g
- Price
- $129
- Updated
- 2025/07/31
- Product number
- 277937
- Product name
- 6-
- Packaging
- 250mg
- Price
- $368
- Updated
- 2021/12/16
4-(Diethylamino)salicylaldehyde Chemical Properties,Usage,Production
Chemical Properties
4-(Diethylamino)salicylaldehyde is beige to purple crystalline powder
Uses
4-(Diethylamino)salicylaldehyde was used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.
Uses
4-(Diethylamino)salicylaldehyde is usually used in the synthesis of Schiff-base ligand by monocondensation with diaminomaleonitrile.
Definition
ChEBI: 4-(Diethylamino)salicylaldehyde is a hydroxybenzaldehyde.
Synthesis
68-12-2
91-68-9
17754-90-4
The temperature of the reaction system was maintained at 5-10 °C under continuous stirring and phosphorus oxychloride (POCl3, 2.75 mL, 0.03 mol) was slowly added dropwise to N,N-dimethylformamide (DMF, 3.65 mL, 0.05 mol). Subsequently, 3-(N,N-diethylamino)phenol (0.01 mmol) dissolved in DMF (6 mL) was slowly added to the above cooled mixture at the same temperature. The reaction mixture was stirred at a constant temperature at 75 °C for 4 hours. After the reaction was completed, the mixture was cooled to room temperature and slowly poured into 60 mL of ice water. The reaction mixture was neutralized with sodium carbonate solution and a brown solid precipitated. The solid product was collected by filtration, washed with cold water, dried and recrystallized from ethanol to give the pure 4-(diethylamino)salicylaldehyde in 80% yield with a melting point of 62 °C (literature value: 62 °C).
References
[1] Organic and Biomolecular Chemistry, 2017, vol. 15, # 12, p. 2575 - 2584
[2] Journal of Fluorescence, 2015, vol. 25, # 6, p. 1615 - 1628
[3] Chemical Communications, 2016, vol. 52, # 60, p. 9434 - 9437
[4] Chemistry Letters, 2011, vol. 40, # 3, p. 279 - 281
[5] Patent: US2789125, 1953,
4-(Diethylamino)salicylaldehyde Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-(Diethylamino)salicylaldehyde manufacturers
- Product
- 4-(Diethylamino)salicylaldehyde 17754-90-4
- Price
- US $30.00-10.00/KG
- Min. Order
- 50KG
- Purity
- 99%
- Supply Ability
- 500000kg
- Release date
- 2024-10-25
- Product
- 4-(Diethylamino)salicylaldehyde 17754-90-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 10000KGS
- Release date
- 2025-03-15
- Product
- 4-(Diethylamino)salicylaldehyde 17754-90-4
- Price
- US $95.00-62.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2023-09-14