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Tetramethrin

Product Name
Tetramethrin
CAS No.
7696-12-0
Chemical Name
Tetramethrin
Synonyms
TTM;Doom;sp1103;biwenan;py-kill;sp-1103;Butamin;ent27339;fmc-9260;insectol
CBNumber
CB9420520
Molecular Formula
C19H25NO4
Formula Weight
331.41
MOL File
7696-12-0.mol
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Tetramethrin Property

Melting point:
60-80°C
Boiling point:
468.68°C (rough estimate)
Density 
d2020 1.108
vapor pressure 
0.94×10-3 Pa (30 °C)
refractive index 
nD21.5 1.5175
storage temp. 
Sealed in dry,2-8°C
Water Solubility 
1.83 mg l-1 (25 °C)
form 
neat
pka
-2.55±0.20(Predicted)
Merck 
13,9296
BRN 
8807938
Stability:
Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference
7696-12-0(CAS DataBase Reference)
NIST Chemistry Reference
Tetramethrin(7696-12-0)
EPA Substance Registry System
Tetramethrin (7696-12-0)
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Safety

Hazard Codes 
Xn,N
Risk Statements 
20-50/53
Safety Statements 
24/25-61-60
RIDADR 
UN 2588
WGK Germany 
2
RTECS 
GZ1730000
HazardClass 
9
PackingGroup 
III
HS Code 
29251900
Hazardous Substances Data
7696-12-0(Hazardous Substances Data)
Toxicity
LD50 orally in mice: 1000 mg/kg (Kato)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
45681
Product name
Tetramethrin
Purity
PESTANAL
Packaging
250mg-r
Price
$80.7
Updated
2020/08/18
Sigma-Aldrich
Product number
45681
Product name
Tetramethrin
Purity
PESTANAL?, analytical standard
Packaging
250 mg
Price
$83.3
Updated
2021/03/22
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Tetramethrin Chemical Properties,Usage,Production

Description

Form: Colorless crystals with slight pyrethrum-like odor

Chemical Properties

white crystals or powder

Uses

Tetramethrin is a synthetic pyrethroid pesticide used in large-scale commercial agricultural applications as well as in consumer products for domestic purposes.

Uses

Insecticide.

Uses

Tetramethrin is used to control flies, wasps, cockroaches and other insects in public health, home and garden situations.

General Description

Colorless crystals with slight odor. Non corrosive. Used as an insecticide.

Air & Water Reactions

Hydrolysis occurs with strong acid or base.

Reactivity Profile

A pyrethroid. Tetramethrin is an ester and nitrile. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Agricultural Uses

Insecticide: Tetramethrin is often formulated as an aerosol and used primarily for indoor pest control or in mosquito coils. It is also used in shampoos to control fleas and ticks on pets. It is often formulated with other insecticides and synergists. Not approved for use in EU countries. Registered for use in the U.S.

Trade name

FMC 9260®; ENT-27339; EVERCIDE INTERMEDIATE® 2265 (tetramethrin + fenvalerate); MULTICIDE®; NEO-PYNAMIN®; NEOPYNAMINE®; NEOPYNAMIN FORTE®; NIAGARA®-9260; NIA®- 9260; PHTHALTHRIN®; SP-1103; SUMITOMO® SP-1103

Metabolic pathway

Tetramethrin was the second synthetic pyrethroid to be produced commercially (1964). The compound has a rapid knock-down action and a reasonable killing activity which is enhanced by use with synergists. It is usually used with piperonyl butoxide and in the presence of other insecticides. It has two chiral centres, both in the acid group, and therefore is a 1 RS-cis-trans mixture. A(1R)-rich product containing cis- and trans-isomers in the ratio 20:80 is also used in public health; this is named dtetramethrin. The two products will not be distinguished here because metabolic studies have been performed with various combinations of isomers. Most published information relates to its mode of action in insects and its metabolism in rodents. This is a reflection of its limited outdoor and field use.

Degradation

Tetramethrin is a stable chemical but it is base labile and it is also sensitive to strong acids. It is hydrolysed to (1RS)-cis-trans-2,2-dimethyl-3-(2- methylprop-1-enyl)cyclopropanecarboxylic acid (chrysanthemic acid, 2) and tetrahydrophthalimide (4). It is oxidised by m-chloroperbenzoic acid to form epoxy-tetramethrin (5) which is ring-opened to the diol (6) in dilute aqueous acid (Smith and Casida, 1981). This reaction has been postulated as initiating the opening of the cyclopropane ring with the ultimate formation of CO 2 in biological systems (see below). Another biomimetic reaction of tetramethrin and its ester cleavage product 4 is Michael addition of thiols to the double bond. Glutathionyl-tetramethrin (7) is formed by incubation of the constituents in buffered aqueous methanol (Smith et al., 1982). Its formation on incubation with mouse liver microsomes is probably non-enzymatic. At the time of this discovery there appeared to be no equivalent reaction in vivo but the more recent discovery of sulfonate metabolites (see below) demonstrates its role.
The chrysanthemic acid esters are very sensitive to photodegradation, being subject to ring-opening initiated by the formation of epoxides such as 5 (Ruzo et al., 1982) as described under bioallethrin and phenothrin. Isomerisation was observed only in de-oxygenated benzene solution because photo-oxidative degradation predominated under most conditions. Many products were seen in oxygenated benzene solution and in a thin film in sunlight.
These chemical and photochemical reactions are summarised in Scheme 1.

Toxicity evaluation

Acute oral LD50 for rats: >5,000 mg/kg

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Tetramethrin Suppliers

Guangzhou Zeqin Pharmaceutical Technology Co. , Ltd.
Tel
Fax
3181266507@qq.c
Email
3181266507@qq.com
Country
China
ProdList
134
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58
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
BEST-REAGENT
Tel
400-1166-196;028-84555506- ;028-84555506-
Email
cdhxsj@163.com;1955352637@qq.com;cdhxsj@163.com
Country
China
ProdList
11718
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
028-85911938-
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9750
Advantage
55
T&W GROUP
Tel
021-61551611-
Fax
+86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9646
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58
Huge Rise International Limited
Tel
13905483216 Mr Tao
Fax
+86 (538) 698-1196
Email
taoanye@163.com
Country
China
ProdList
13
Advantage
59
Cheng Du Micxy Chemical Co.,Ltd
Tel
028-85632863-
Fax
028-85632863
Email
sales@micxy.com;
Country
China
ProdList
13065
Advantage
58
Shanghai Aladdin Bio-Chem Technology Co.,LTD
Tel
021-20337333-801
Fax
021-50323701
Email
market@aladdin-e.com
Country
China
ProdList
24980
Advantage
65
The future of Shanghai Industrial Co., Ltd.
Tel
021-61552785
Fax
021-55660885
Email
sales@shshiji.com
Country
China
ProdList
9542
Advantage
55
Nanjing Sunlida Biological Technology Co., Ltd.
Tel
025-57798810- ;025-57798810-
Fax
025-57019371
Email
sales@sunlidabio.com;sales@sunlidabio.com
Country
China
ProdList
3756
Advantage
55
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View Lastest Price from Tetramethrin manufacturers

Hubei Langyou International Trading Co., Ltd
Product
Tetramethrin 7696-12-0
Price
US $100.00/KG
Min. Order
1KG
Purity
95%
Supply Ability
10000 tons
Release date
2021-08-19
Zhuozhou Wenxi import and Export Co., Ltd
Product
Tetramethrin 7696-12-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-11
Zhuozhou Wenxi import and Export Co., Ltd
Product
Tetramethrin 7696-12-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-09

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