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Phthalic acid

Product Name
Phthalic acid
CAS No.
88-99-3
Chemical Name
Phthalic acid
Synonyms
NSC 5348;Phthalsure;Sunftal 20;THALIC ACID;phthalicaci;AURORA 15195;PATHALIC ACID;PHTHALIC ACID;acidephtalique;Acide phtalique
CBNumber
CB6289456
Molecular Formula
C8H6O4
Formula Weight
166.13
MOL File
88-99-3.mol
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Phthalic acid Property

Melting point:
210-211 °C (dec.)(lit.)
Boiling point:
214.32°C (rough estimate)
Density 
1.593
vapor pressure 
7.8 hPa (191 °C)
refractive index 
1.5100 (estimate)
Flash point:
168 °C
storage temp. 
Store below +30°C.
solubility 
methanol: 0.1 g/mL, clear
pka
2.89(at 25℃)
form 
Powder
color 
White
PH
2 (5g/l, H2O, 20℃)
Water Solubility 
7 g/L (25 ºC)
Merck 
14,7371
BRN 
608199
Stability:
Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey
XNGIFLGASWRNHJ-UHFFFAOYSA-N
CAS DataBase Reference
88-99-3(CAS DataBase Reference)
NIST Chemistry Reference
1,2-Benzenedicarboxylic acid(88-99-3)
EPA Substance Registry System
Phthalic acid (88-99-3)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36-37/39
WGK Germany 
1
RTECS 
TH9625000
TSCA 
Yes
HS Code 
29173980
Hazardous Substances Data
88-99-3(Hazardous Substances Data)
Toxicity
LD50 orally in rats: 7.9 g/kg (Shaffer)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H303May be harmfulif swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
8.22298
Product name
Phthalic acid
Purity
for synthesis
Packaging
100 g
Price
$30.15
Updated
2021/03/22
Sigma-Aldrich
Product number
8.22298
Product name
Phthalic acid
Purity
for synthesis
Packaging
1 kg
Price
$118.4
Updated
2021/03/22
Sigma-Aldrich
Product number
402915
Product name
Phthalic acid
Purity
ACS reagent, ≥99.5%
Packaging
1kg
Price
$170
Updated
2021/03/22
Sigma-Aldrich
Product number
Y0000766
Product name
Phthalic acid
Purity
European Pharmacopoeia (EP) Reference Standard
Price
$190
Updated
2021/03/22
Sigma-Aldrich
Product number
1535899
Product name
Phthalic acid
Purity
United States Pharmacopeia (USP) Reference Standard
Packaging
50mg
Price
$406
Updated
2021/03/22
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Phthalic acid Chemical Properties,Usage,Production

Description

Phthalic acid is an aromatic dicarboxylic acid, with formula C6H4(CO2H)2. It is an isomer of isophthalic acid and terephthalic acid. Although phthalic acid is of modest commercial importance, the closely related derivative phthalic anhydride is a commodity chemical produced on a large scale.

Chemical Properties

PHTHALIC ACID,C6H4(COOH)2, mp 208 °C (ortho), 330 °C (meta and iso), the ortho form sublimes and the meta and iso forms decompose with heat, sp gr 1.593 (ortho). Phthalic acid is very slightly soluble in H2O, soluble in alcohol, and slightly soluble in ether. The solid form is colorless, crystalline

Uses

It is a dibasic acid, with pKa's of 2.89 and 5.51. The mono potassium salt, potassium hydrogen phthalate is a standard acid in analytical chemistry. Typically phthalate esters are prepared from the widely available phthalic anhydride. Reduction of phthalic acid with sodium amalgam in the presence of water gives the 1,3- cyclohexadiene derivative.

Uses

Organic reagent used to synthesize phthalates.

Definition

ChEBI: A benzenedicarboxylic acid cosisting of two carboxy groups at ortho positions.

Definition

phthalic acid: colourlesscrystalline dicarboxylic acid,C6H4(COOH)2; r.d. 1.6; m.p. 207°C.The two –COOH groups are substitutedon adjacent carbon atoms ofthe ring, the technical name beingbenzene-1,2-dicarboxylic acid. Theacid is made from phthalic anhydride(benzene-1,2-dicarboxylic anhydride,C8H4O3), which is made by the catalyticoxidation of naphthalene. Theanhydride is used in making plasticizersand polyester resins.

Production Methods

Phthalic acid is produced by the catalytic oxidation of naphthalene directly to phthalic anhydride and a subsequent hydrolysis of the anhydride.
Phthalic acid was first obtained by French chemist Auguste Laurent in 1836 by oxidizing naphthalene tetrachloride. Believing the resulting substance to be a naphthalene derivative, he named it "naphthalic acid". After the Swiss chemist Jean Charles Galissard de Marignac determined its correct formula, Laurent gave it its present name. Manufacturing methods in the nineteenth century included oxidation of naphthalene tetrachloride with nitric acid, or, better, oxidation of the hydrocarbon with fuming sulfuric acid, using mercury or mercury(II) sulfate as a catalyst.

Synthesis Reference(s)

The Journal of Organic Chemistry, 30, p. 2414, 1965 DOI: 10.1021/jo01018a074

General Description

White crystals or fine white powder.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

Phthalic acid is a carboxylic acid. Phthalic acid is sensitive to exposure to extreme heat. Phthalic acid reacts violently with nitric acid. Phthalic acid is incompatible with sodium nitrite. Phthalic acid is also incompatible with oxidizers. .

Fire Hazard

Phthalic acid is combustible.

Safety Profile

Moderately toxic by ingestion and intraperitoneal routes. A skin and mucous membrane irritant. Combustible when heated. In the form of dust (anhydride) it can explode. Mixtures with sodmm nitrite explode when heated. Violent reaction with HNO3. When heated to decomposition it emits acrid smoke and irritating fumes. Used in synthesis of dyes and dyestuffs, in medcines and perfumes.

Safety

The toxicity of phthalic acid is low with LD50 (mouse) of 550 mg/kg. However, many phthalate esters have been implicated as endocrine disruptors.

Purification Methods

Crystallise phthalic acid from water. [Beilstein 9 IV 3167.]

Isomers

Phthalic acid is one of three isomers of benzene dicarboxylic acid, the others being iso phthalic acid and terephthalic acid. Sometimes the term "phthalic acids" is used to refer to this family of isomers, but in the singular, "phthalic acid", refers exclusively to the ortho- isomer.

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Phthalic acid Suppliers

Shenzhen Vtolo Chemicals Co., Ltd.
Tel
13534282526
Fax
+86 0755 2767-0086-806
Email
yolanda@vtolo.com
Country
China
ProdList
231
Advantage
55
J & K SCIENTIFIC LTD.
Tel
010-82848833- ;010-82848833-
Fax
86-10-82849933
Email
jkinfo@jkchemical.com;market6@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
21-61259100-
Fax
86-21-61259102
Email
sh@meryer.com
Country
China
ProdList
40265
Advantage
62
Alfa Aesar
Tel
400-610-6006; 021-67582000
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30160
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386 / 800-988-0390
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24555
Advantage
81
Beijing dtftchem Technology Co., Ltd.
Tel
010-60275820-
Fax
010-60270825
Email
elainezt@sina.com
Country
China
ProdList
1401
Advantage
62
BeiJing Hwrk Chemicals Limted
Tel
0757-86329057-
Fax
0757-86311057
Email
kennyrong@hwrkchemical.com
Country
China
ProdList
17295
Advantage
55
Energy Chemical
Tel
021-58432009-
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44068
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028-
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12281
Advantage
60
Adamas Reagent, Ltd.
Tel
400-600-9262
Email
bxy@titansci.com
Country
China
ProdList
13915
Advantage
59
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View Lastest Price from Phthalic acid manufacturers

Hebei Dongdu Import and Export Co. LTD
Product
phthalic acid 88-99-3
Price
US $50000.00/T
Min. Order
1T
Purity
99%
Supply Ability
20tons
Release date
2020-12-17
Hebei Guanlang Biotechnology Co., Ltd.
Product
Phthalic acid 88-99-3
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2021-02-20
Hebei Miaobian Biotechnology Co., Ltd
Product
Phthalic acid 88-99-3
Price
US $10.00/KG
Min. Order
1KG
Purity
99.99
Supply Ability
10Ton
Release date
2020-12-21

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