Boc-Hyp-OH

Product Name: Boc-Hyp-OH
CAS No.: 13726-69-7
Chemical Name: Boc-Hyp-OH
Synonyms: (2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid;BOC-HYP-OH;BOC-HYP;BOC-L-HYP-OH;N-BOC-L-HYDROXYPROLINE;(4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline;(2S,4R)-1-Boc-4-hydroxypyrrolidine-2-carboxylic Acid;N-ter;Teneint-E;BOC-TRANS-HYP-OH
CBNumber: CB5411793
Molecular Formula: C10H17NO5
Formula Weight: 231.25
MOL File: 13726-69-7.mol

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Boc-Hyp-OH Property

Melting point:: 123-127 °C(lit.)
alpha: -78 º (in H2O)
Boiling point:: 390.9±42.0 °C(Predicted)
Density: 1.312±0.06 g/cm3(Predicted)
refractive index: -68 ° (C=1, MeOH)
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
pka: 3.80±0.40(Predicted)
form: Powder
color: White to off-white
optical activity: [α]20/D 53.5±2°, c = 1% in DMF
Water Solubility: very faint turbidity
BRN: 4295484
InChIKey: BENKAPCDIOILGV-RQJHMYQMSA-N
CAS DataBase Reference: 13726-69-7(CAS DataBase Reference)
EPA Substance Registry System: (2S,4R)-1-tert-Butyl 4-hydroxy-1,2-pyrrolidinecarboxylate (13726-69-7)

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Safety

Safety Statements: 22-24/25
WGK Germany: 3
HS Code: 2933 99 80
HazardClass: IRRITANT

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.53026
Product name: Boc-Hyp-OH (cryst)
Purity: Novabiochem?
Packaging: 25g
Price: $344
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.53026
Product name: Boc-Hyp-OH (cryst)
Purity: Novabiochem?
Packaging: 100g
Price: $1030
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15544
Product name: Boc-Hyp-OH
Purity: ≥98.0% (TLC)
Packaging: 5g
Price: $36.6
Updated: 2024/03/01

Sigma-Aldrich

Product number: 15544
Product name: Boc-Hyp-OH
Purity: ≥98.0% (TLC)
Packaging: 25g
Price: $150
Updated: 2024/03/01

TCI Chemical

Product number: B1635
Product name: trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline
Purity: >98.0%(T)
Packaging: 5g
Price: $18
Updated: 2024/03/01

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Boc-Hyp-OH Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

Boc-Hyp-OH is used in the preparation of hydroxyproline derivatives. It is an intermediate in the synthesis of Fosinopril-d5 Sodium Salt (F727803), the labeled analogue of Fosinopril Sodium Salt (F727800), a phosphinic acid containing angiotensin converting enzyme (ACE) inhibitor. Antihypertensive.

Biological Activity

Boc-Hyp-OH is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). It is also a alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.

Boc-Hyp-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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Boc-Hyp-OH Suppliers

Americas 1 Belgium 2 Canada 1 China 367 Europe 3 France 3 Germany 8 Hungary 1 India 25 Japan 5 South Korea 1 Switzerland 4 The Netherlands 1 United Kingdom 13 United States 57 Global 492

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View Lastest Price from Boc-Hyp-OH manufacturers

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Boc-L-Hydroxyproline 13726-69-7
Price: US $0.00-0.00/Kg/Drum
Min. Order: 1KG
Purity: 99%HPLC
Supply Ability: 10 Tons
Release date: 2021-06-16

WUHAN FORTUNA CHEMICAL CO., LTD

Product: Boc-Hyp-OH 13726-69-7
Price: US $0.00/Kg/Drum
Min. Order: 1KG
Purity: 98%min
Supply Ability: 500kgs
Release date: 2021-09-24

Henan Bao Enluo International TradeCo.，LTD

Product: Boc-L-Hydroxyproline 13726-69-7
Price: US $100.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 1000tons
Release date: 2023-07-20

13726-69-7, Boc-Hyp-OHRelated Search:

L-Hydroxyproline BOC-D-PHE-OSU Boc-D-Valine 1-BOC-D-PYROGLUTAMIC ACID ETHYL ESTER Methyl N-(tert-butoxycarbonyl)-L-threoninate Boc-L-serine methyl ester BOC-GUANIDINE BOC-L-HYDROXYPROLINE METHYL ESTER,(2S,4R)-BOC 4-HYDROXYPROLINE METHYL ESTER,BOC-HYP-OME / BOC-L-HYDROXYPROLINE METHYL ESTER BOC-HYP(BZL)-OH 1-Boc-L-hydroxyproline ethyl ester N-Boc-trans-4-tosyloxy-L-proline methyl ester (2S, 4R)-BOC-GAMMA-MSO-PROLINE METHYL ESTER Boc-Hyp-OH BOC-CIS-HYDROXYPROLINE-OME L-Proline (2S,4R)-BOC-4-(2-NAPHTHYLMETHOXY)-PYRROLIDINE-2-CARBOXYLIC ACID BOC-HYP-OH DCHA (2S,4R)-BOC-4-(2-NAPHTHYLOXY)-PYRROLIDINE-2-CARBOXYLIC ACID

(2S,4R)-1-(tert-butoxycarbonyl)-4-hydroxypyrrolidine-2-carboxylic acid

(2S,4R)-N-t-Butoxycarbonyl-4-hydroxypyrrolidine-2-carboxylic Acid

Boc-(2S,4R)-4-Hydroxy-2-pyrrolidinecarboxylic Acid

N-ter

N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline ,98%

Boc-L-trans-hydroxyproline(Boc-trans-Hyp-OH) ,98.5%(HPLC)

1,2-Pyrrolidinedicarboxylicacid,4-hydroxy-,1-(1,1-diMethylethyl)ester,(2S,4R)-

(2S)-1-[(tert-butoxy)carbonyl]-4-hydroxypyrrolidine-2-carboxylic acid

trans-N-Boc-4-hydroxy-L-proline trans-Boc-Hyp-OH

(2S,4R)-4-Hydroxy-1,2-pyrrolidinedicarboxylic acid 1-(tert-butyl) ester

(2S,4R)-1-(tertbutoxycarbonyl-4-hydroxypyrrolidine acid

Boc-Hyp-OH, >=98.0%

<i>trans</i>-N-(<i>tert-</i>Butoxycarbonyl)-4-hydroxy-L-proline

N-Boc-(2S,4R)-4-hydroxyproline

BOC-(2S,4R)-(-)-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID

BOC-L-HYDROXYPROLINE

BOC-L-HYP-OH

BOC-L-4-HYDROXYPROLINE

BOC-HYDROXYPROLINE

BOC-HYP-OH

BOC-TRANS-HYP-OH

BOC-TRANS-4-HYDROXY-L-PROLINE

BOC-L-T-4-HYDROXYPROLINE

BOC-L-TRANS-4-HYDROXYPROLINE

Boc-L-trans-4-hydroxyproline≥ 99% (Assay)

Boc-Hyp-OH (cryst) Novabiochem

Boc-Hyp-OH >=98.0% (TLC)

(2S,4R)-N-ALPHA-T-BUTOXYCARBONYL-4-HYDROXYPYRROLIDINE-2-CARBOXYLIC ACID

RARECHEM EM WB 0136

N-T-BOC-TRANS-4-HYDROXY-L-PROLINE

N-(TERT-BUTOXYCARBONYL)-L-4-HYDROXYPROLINE

N-TERT-BUTOXYCARBONYL-L-HYDROXYPROLINE

N-ALPHA-TERT-BUTYLOXYCARBONYL-L-4-HYDROXYPROLINE

N-ALPHA-T-BUTOXYCARBONYL-TRANS-4-HYDROXY-L-PROLINE

（2S，4R)-1-（tertbutoxycarbonyl）-4-hydroxypyrrolidine carboxylic acid

(Tert-Butoxy)Carbonyl Hyp-OH (Hyp of Animal Origin)

(Tert-Butoxy)Carbonyl Hyp-OH (Hyp of Non-Animal Origin)

Teneint-E

(4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline

BOC-HYPOZANTHINE extrapure

Boc-L-hydroxyproline, trans-N-(tert-Butoxycarbonyl)-4-hydroxy-L-proline

trans-Boc-Hyp-OH

trans-N-Boc-4-hydroxy-L-proline

1-[(tert-Butoxy)carbonyl]-4-hydroxy-L-proline

(2S,4R)-N-Boc-trans-4-hydroxy-L-proline

(2S,4R)-4-Hydroxypyrrolidine-2-carboxylic acid, N-BOC protected 97%

N-ALPHA-T-BOC-TRANS-4-HYDROXY-L-PROLINE

N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE

N-ALPHA-T-BOC-L-HYDROXYPROLINE

N-ALPHA-T-BOC-L-TRANS-4-HYDROXYPROLINE

N-BOC-TRANS-4-HYDROXY-L-PROLINE

N-BOC-L-4-HYDROXYPROLINE

N-BOC-L-TRANS-4-HYDROXYPROLINE

N-BOC-4-HYDROXY-L-PROLINE

TRANS-N-(TERT-BUTOXYCARBONYL)-4-HYDROXY-L-PROLINE

Butoxycarbonylhydroxypyroline

Boc-4-hydroxy-L-proline

TRANS-N-(TERT-BUTOXYCARBONYL)-4-HYDROXY-