ChemicalBook > CAS DataBase List > N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester

Product Name
N-Boc-trans-4-Hydroxy-L-proline methyl ester
CAS No.
74844-91-0
Chemical Name
N-Boc-trans-4-Hydroxy-L-proline methyl ester
Synonyms
1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-HYP-OME;Boc-L-Hyp-OMe;N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER;1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;GOSO-001;BOC-L-Hyp Methyl ester;BOC-HYDROXYPROLINE-OME;N-Boc-trans-4-hydroxy-L;(Tert-Butoxy)Carbonyl Hyp-OMe
CBNumber
CB2207339
Molecular Formula
C11H19NO5
Formula Weight
245.27
MOL File
74844-91-0.mol
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N-Boc-trans-4-Hydroxy-L-proline methyl ester Property

Melting point:
92-96 °C (lit.)
alpha 
-65 º (c=1 CHCl3)
Boiling point:
132°C/0.05mmHg(lit.)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in chloroform, dichloromethane and ethyl acetate.
form 
Crystalline Powder
pka
14.27±0.40(Predicted)
color 
White to light beige
optical activity
[α]20/D -65°, c = 1% in chloroform
InChI
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey
MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES
N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP
0.813 at 25℃
CAS DataBase Reference
74844-91-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
639737
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester
Purity
97%
Packaging
5g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
B3843
Product name
N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester
Purity
>95.0%(GC)
Packaging
1g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
B3843
Product name
N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester
Purity
>95.0%(GC)
Packaging
5g
Price
$97
Updated
2024/03/01
Alfa Aesar
Product number
H59027
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Packaging
1g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
H59027
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Packaging
5g
Price
$99.65
Updated
2024/03/01
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N-Boc-trans-4-Hydroxy-L-proline methyl ester Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

A potential iNOS inhibitor.

Uses

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Uses

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester roline scaffold.

N-Boc-trans-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-trans-4-Hydroxy-L-proline methyl ester Suppliers

Americas 1 Belgium 5 Canada 4 China 347 Europe 4 Germany 6 India 14 Japan 4 Switzerland 3 United Kingdom 10 United States 50 Global 448
Zepeptide Biotechnology (Shijiazhuang) Co., LTD
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13383293380 18032131480
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649498984@qq.com
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China
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Shanghai Xinxin Pharmaceutical Technology Co., Ltd.
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13671725141
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hickle@yeah.net
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China
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Nanjing Ally Chemical S&T Co., Ltd.
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025-025-58367986 18913956109
Fax
QQ:3209878052
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amy.xiang@ally-chem.com
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China
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Shanxi Bethlehem Pharm-Tech Co.,Ltd.
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19135651206 19135651206
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243332738@qq.com
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China
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J & K SCIENTIFIC LTD.
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010-82848833 400-666-7788
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86-10-82849933
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jkinfo@jkchemical.com
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006608290; 18621169109
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86-21-61259102
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market03@meryer.com
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China
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ChemFuture PharmaTech (Jiangsu) Ltd
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5108538618
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86 510 85386988-8017
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suger.wang@chemfuture.com
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China
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Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
ProdList
30132
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Sichuan Tongsheng Amino acids Co.,Ltd.
Tel
0838-2809458 13350585791
Fax
+86-838-2274207
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pharm@biots.cn
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China
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TAIYUAN RHF CO.,LTD.
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+86 351 7031519
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+86 351 7031519
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sales@RHFChem.com
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China
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View Lastest Price from N-Boc-trans-4-Hydroxy-L-proline methyl ester manufacturers

Henan Fengda Chemical Co., Ltd
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Nanjing Fred Technology Co., Ltd
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-02
Hebei Yanxi Chemical Co., Ltd.
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-29

74844-91-0, N-Boc-trans-4-Hydroxy-L-proline methyl esterRelated Search:

Tribenuron methyl Basic Violet 1 L-PROLINE-(4-3H(N)) CHLOROPHOSPHONAZO III Methylparaben BOC-L-Proline D-Proline L-Hydroxyproline Methyl salicylate cis-4-Hydroxy-L-proline Methanol Kresoxim-methyl Methyl acrylate N-Boc-trans-4-tosyloxy-L-proline methyl ester N-Boc-trans-4-amino-L-proline methyl ester hydrochloride N-Boc-trans-4-amino-L-proline methyl ester Methyl 1-tert-butoxycarbonyl-4-hydroxy-L-proline ethyl ester

  • N-T-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-(TERT-BUTOXYCARBONYL)-TRANS-HYDROXYL-L-PROLINE METHYL ESTER
  • N-ALPHA-T-BUTOXYCARBONYL-L-HYDROXYPROLINE METHYL ESTER
  • N-BOC-TRANS-4-HYDROXYL-L-PROLINE METHYL ESTER
  • N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-BOC-L-TRANS-4-HYDROXY-PROLINE METHYL ESTER
  • (2R,4R)-4-HYDROXY-PYRROLIDINE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-METHYL ESTER
  • (2S,4R)-1-(TERT-BUTOXYCARBONYL)-2-CARBOMETHOXY-4-HYDROXYPYRROLIDINE
  • (2S,4R)-BOC 4-HYDROXYPROLINE METHYL ESTER
  • (2S,4R)-1-BOC-4-hydroxy pyrrolidine-2-carboxylic acid methyl ester
  • 1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate
  • 1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • (2S,4R)-1-tert-butyl 2-Methyl 4-hydroxypyrrolidine-1,2-dicarboxy
  • (2S,4R)-1-(tert-Butoxycarbonyl)-4-hydroxy-2-(methoxycarbonyl)pyrrolidine, trans-1-(tert-Butoxycarbonyl)-4-hydroxy-L-proline methyl ester
  • 1-(tert-butyl) 2-Methyl (2S,4R)-4-hydroxytetrahydro-1H-pyrrole-1,2-dicarboxylate
  • (2S,4R)-1-tert-butyl 2-Methyl 4-hydro×ypyrrolidine-1,2-dicarbo×ylate
  • 1-(tert-butyl) 2-Methyl (2S,4R)-4-hydro×ytetrahydro-1H-pyrrole-1,2-dicarbo×ylate
  • N-Boc-trans-4-hydroxy-L-proline Methyl Ester trans-Boc-Hyp-OMe 1-tert-Butyl 2-Methyl (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylate (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
  • 1,2-Pyrrolidinedicarboxylic acid, 4-hydroxy-, 1-(1,1-diMethylethyl) 2-Methyl ester, (2S,4R)-
  • N-Boc-trans-4-hydroxy-L-proline methyl ester 97%
  • N-BOC-L-Hydroxyproline methyl ester
  • BOC-L-Hyp Methyl ester
  • Boc-L-Hyp-OMe
  • trans-N-Boc-4-hydroxy-L-proline Methyl Ester
  • <i>N</i>-(<i>tert</i>-Butoxycarbonyl)-<i>trans</i>-4-hydroxy-L-proline methyl ester
  • 1-tert-butyl 2-methyl (2S,4R)-4-hydroxy-1,2-pyrrolidinedicarboxylate
  • O1-tert-Butyl O2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • (2S,4R)-N-Boc-trans-4-hydroxy-L-proline methyl ester
  • BOC-L-4-HYDROXYPROLINE METHYL ESTER
  • BOC-HYP-OME
  • BOC-HYDROXYPROLINE-OME
  • BOC-L-T-4-HYDROXYPROLINE METHYL ESTER
  • BOC-L-HYDROXYPROLINE METHYL ESTER
  • BOC-L-4-TRANS-HYDROXYPROLINE METHYL ESTER
  • BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER
  • N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL &
  • N-Boc-trans-hydro-L-prolinemethylester
  • N-tert-Butoxycarbonyl-trans-4-hydroxy-L-proline methyl ester
  • N-(tert-Butoxycarbonyl)-trans-hydroxy-L-proline methyl ester
  • (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester
  • Methyl (4R)-N-Boc-4-hydroxy-L-prolinate
  • N-tert-Butoxycarbonyl-L-hydroxyproline Methyl Ester
  • BOC-HYP-OME / BOC-L-HYDROXYPROLINE METHYL ESTER
  • N-BOC-trans-4-Hydroxy-L-proline methyl ester,97%
  • N-BOC-transydro-L-prolinemethylester
  • Boc-L-4-trans-hydroxyproline methyl ester≥ 99% (HPLC, Chiral purity)
  • trans-N-Boc-4-hydroxy-L-proline Methyl Ester,99%e.e.
  • 1-O-tert-butyl 2-O-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate
  • (Tert-Butoxy)Carbonyl Hyp-OMe
  • GOSO-001
  • (2S,4R)-N-Boc-4-hydroxyproline methyl ester
  • N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester &gt
  • N-Boc-trans-4-hydroxy-L
  • (2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl 2-Methyl Ester
  • N-BOC-TRANS-4-HYDROXY-L-PROLINE METHYL ESTER,74844-91-0
  • N-Boc-trans-4-Hydroxy-L-proline methyl ester USP/EP/BP
  • Tert butoxycarbonyl-l-hydroxyproline methyl ester