ChemicalBook > CAS DataBase List > N-Boc-trans-4-Hydroxy-L-proline methyl ester

N-Boc-trans-4-Hydroxy-L-proline methyl ester

Product Name
N-Boc-trans-4-Hydroxy-L-proline methyl ester
CAS No.
74844-91-0
Chemical Name
N-Boc-trans-4-Hydroxy-L-proline methyl ester
Synonyms
1-tert-Butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate;BOC-HYP-OME;Boc-L-Hyp-OMe;N-BOC-4-HYDROXY-L-PROLINE METHYL ESTER;1-tert-butyl 2-methyl (2S,4R)-4-hydroxypyrrolidine-1,2-dicarboxylate;GOSO-001;BOC-L-Hyp Methyl ester;BOC-HYDROXYPROLINE-OME;N-Boc-trans-4-hydroxy-L;(Tert-Butoxy)Carbonyl Hyp-OMe
CBNumber
CB2207339
Molecular Formula
C11H19NO5
Formula Weight
245.27
MOL File
74844-91-0.mol
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N-Boc-trans-4-Hydroxy-L-proline methyl ester Property

Melting point:
92-96 °C (lit.)
alpha 
-65 º (c=1 CHCl3)
Boiling point:
132°C/0.05mmHg(lit.)
Density 
1.216±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
solubility 
Soluble in chloroform, dichloromethane and ethyl acetate.
form 
Crystalline Powder
pka
14.27±0.40(Predicted)
color 
White to light beige
optical activity
[α]20/D -65°, c = 1% in chloroform
InChI
InChI=1S/C11H19NO5/c1-11(2,3)17-10(15)12-6-7(13)5-8(12)9(14)16-4/h7-8,13H,5-6H2,1-4H3/t7-,8+/m1/s1
InChIKey
MZMNEDXVUJLQAF-SFYZADRCSA-N
SMILES
N1(C(OC(C)(C)C)=O)C[C@H](O)C[C@H]1C(OC)=O
LogP
0.813 at 25℃
CAS DataBase Reference
74844-91-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xn
Risk Statements 
20/21/22-36/37/38
Safety Statements 
24/25-36-26
WGK Germany 
3
HazardClass 
IRRITANT
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
639737
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester
Purity
97%
Packaging
5g
Price
$26
Updated
2024/03/01
TCI Chemical
Product number
B3843
Product name
N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester
Purity
>95.0%(GC)
Packaging
1g
Price
$33
Updated
2024/03/01
TCI Chemical
Product number
B3843
Product name
N-(tert-Butoxycarbonyl)-trans-4-hydroxy-L-proline Methyl Ester
Purity
>95.0%(GC)
Packaging
5g
Price
$97
Updated
2024/03/01
Alfa Aesar
Product number
H59027
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Packaging
1g
Price
$30.65
Updated
2024/03/01
Alfa Aesar
Product number
H59027
Product name
N-Boc-trans-4-hydroxy-L-proline methyl ester, 97%
Packaging
5g
Price
$99.65
Updated
2024/03/01
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N-Boc-trans-4-Hydroxy-L-proline methyl ester Chemical Properties,Usage,Production

Chemical Properties

Clear Colourless Oil

Uses

A potential iNOS inhibitor.

Uses

It is used in the synthesis of For-Met-Leu-Phe-OMe (fMLF-OMe) analogues based on Met residue replacement by 4-amino-proline scaffold.

Uses

(2S,4R)-4-Hydroxypyrrolidine-1,2-dicarboxylic Acid 1-tert-Butyl Ester 2-Methyl Ester roline scaffold.

N-Boc-trans-4-Hydroxy-L-proline methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-trans-4-Hydroxy-L-proline methyl ester Suppliers

TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23680
Advantage
75
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View Lastest Price from N-Boc-trans-4-Hydroxy-L-proline methyl ester manufacturers

Nanjing Fred Technology Co., Ltd
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1 ton
Release date
2024-01-02
Henan Fengda Chemical Co., Ltd
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $6.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Hebei Yanxi Chemical Co., Ltd.
Product
N-Boc-trans-4-Hydroxy-L-proline methyl ester 74844-91-0
Price
US $20.00-1.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
20 tons
Release date
2023-11-29

74844-91-0, N-Boc-trans-4-Hydroxy-L-proline methyl esterRelated Search:


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