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N-Boc-L-Homoserine

Product Name
N-Boc-L-Homoserine
CAS No.
41088-86-2
Chemical Name
N-Boc-L-Homoserine
Synonyms
Boc-Hse;Boc-HoSer;BOC-HSE-OH;Boc-HSer-OH;Boc-HoSer-OH;Boc-Homoserine;BOC-HOMOSER-OH;BOC-L-HOMOSERINE;N-Boc-L-homoserine;N-T-BOC-L-HOMOSERINE
CBNumber
CB6226376
Molecular Formula
C9H17NO5
Formula Weight
219.24
MOL File
41088-86-2.mol
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N-Boc-L-Homoserine Property

Melting point:
140°C(lit.)
Boiling point:
421.6±40.0 °C(Predicted)
Density 
1.204±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Store in freezer, under -20°C
pka
3.87±0.10(Predicted)
form 
powder to crystal
color 
White to Almost white
optical activity
Consistent with structure
InChI
InChI=1S/C9H17NO5/c1-9(2,3)15-8(14)10-6(4-5-11)7(12)13/h6,11H,4-5H2,1-3H3,(H,10,14)(H,12,13)/t6-/m0/s1
InChIKey
PZEMWPDUXBZKJN-LURJTMIESA-N
SMILES
C(O)(=O)[C@H](CCO)NC(OC(C)(C)C)=O
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Safety

WGK Germany 
3
HS Code 
2922.49.4950
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
B4645
Product name
Boc-Homoser-OH
Packaging
1g
Price
$422
Updated
2023/06/20
Sigma-Aldrich
Product number
B4645
Product name
Boc-Homoser-OH
Packaging
5g
Price
$1510
Updated
2023/06/20
TCI Chemical
Product number
B4025
Product name
N-(tert-Butoxycarbonyl)-L-homoserine
Purity
>98.0%(HPLC)(T)
Packaging
1g
Price
$68
Updated
2025/07/31
TCI Chemical
Product number
B4025
Product name
N-(tert-Butoxycarbonyl)-L-homoserine
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$271
Updated
2025/07/31
TRC
Product number
B656230
Product name
N-Boc-L-Homoserine
Packaging
1g
Price
$155
Updated
2021/12/16
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N-Boc-L-Homoserine Chemical Properties,Usage,Production

Uses

Protected L-Homoserine (H615010).

Synthesis

672-15-1

24424-99-5

41088-86-2

The general procedure for the synthesis of N-Boc-L-homoserine from L-homoserine and di-tert-butyl dicarbonate was as follows: L-homoserine (4.76 g, 40 mmol) and sodium carbonate (Na2CO3, 8.48 g, 80 mmol) were dissolved in water (200 mL). To this solution, 1,4-dioxane (50 mL) was added and stirred for 5 minutes. Di-tert-butyl dicarbonate (Boc2O, 13.80 mL, 60 mmol) was slowly added to the solution under ice bath conditions, followed by stirring the reaction mixture overnight at room temperature. Upon completion of the reaction, the mixture was washed with petroleum ether to remove unreacted organic matter. Additional water was added to the mixture and the pH was adjusted to 2 with 2 mol/L hydrochloric acid (HCl) to induce precipitation of N-Boc-L-homoserine. The formed suspension was extracted with ethyl acetate (EtOAc), and the organic layers were combined and washed sequentially with water and brine. The organic layer was dried with anhydrous sodium sulfate (Na2SO4), filtered and concentrated to give the crude product (about 8.55 g).

References

[1] Journal of Organic Chemistry, 1986, vol. 51, # 26, p. 5047 - 5050
[2] Journal of Peptide Science, 2013, vol. 19, # 5, p. 308 - 314
[3] Journal of Organic Chemistry, 2008, vol. 73, # 8, p. 3212 - 3217
[4] Tetrahedron Letters, 2002, vol. 43, # 33, p. 5727 - 5729
[5] Journal of Organic Chemistry, 2003, vol. 68, # 23, p. 8853 - 8858

N-Boc-L-Homoserine Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Boc-L-Homoserine Suppliers

Americas 1 Belgium 1 Canada 2 China 149 Europe 1 Germany 3 India 4 Japan 4 Poland 1 South Korea 1 Switzerland 3 United Kingdom 6 United States 26 Global 202
ChemPur GmbH
Tel
--
Fax
--
Email
info@ChemPur.de
Country
Germany
ProdList
2737
Advantage
50
ACTIVATE SCIENTIFIC GmbH
Tel
--
Fax
--
Email
info@activate-scientific.com
Country
Germany
ProdList
2856
Advantage
61
Service Chemical Inc.
Tel
--
Fax
--
Email
sales@chemos-group.com
Country
Germany
ProdList
6350
Advantage
71
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View Lastest Price from N-Boc-L-Homoserine manufacturers

Career Henan Chemical Co
Product
N-Boc-L-Homoserine 41088-86-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100Kg
Release date
2020-06-30
Career Henan Chemical Co
Product
(2S)-2-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoic acid 41088-86-2
Price
US $7.00/KG
Min. Order
1KG
Purity
99
Supply Ability
100KG
Release date
2020-06-30

41088-86-2, N-Boc-L-HomoserineRelated Search:

D-Cycloserine tert-Butanol Boc-Ser(tBu)-OH L-ALPHA-PHOSPHATIDYLSERINES, BRAIN, BOVINE L-Homoserine DL-Serine N-Carbobenzyloxyglycine BOC-HYP-OL N-Boc-L-Phenylalaninol N-Boc-exo-3-aminotropane BOC-D-Methionine N-Boc-D-Phenylalaninol BOC-D-ALPHA-T-BUTYLGLYCINE N-Boc-D-Valino Boc-Lys-OH Boc-Hyp-OH 4-tert-Butyl N-[(tert-butoxy)carbonyl]-L-aspartate dicyclohexylamine salt Boc-Asp-OtBu

  • N-[(1,1-Dimethylethoxy)carbonyl]-L-homoserine
  • N-Boc-L-homoserine
  • N-tert-Butoxycarbonyl-L-homoserine
  • Boc-Homoserine
  • N-T-BOC-L-HOMOSERINE
  • N-T-BUTOXYCARBONYL-L-HOMOSERINE
  • (2S)-2-{[(tert-butoxy)carbonyl]amino}-4-hydroxybutanoic acid
  • BOC-L-HOMOSERINE
  • N-tert-Butoxycarbonyl-L-homoserin
  • Boc-HoSer-OH
  • (S)-2-(tert-Butoxycarbonylamino)-4-hydroxybutanoic Acid
  • (2S)-4-hydroxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
  • Boc-L-homoserine、Boc-Homoser-OH
  • BOC-HSE-OH
  • BOC-HOMOSER-OH
  • N-(tert-Butoxycarbonyl)-L-homoserine &gt
  • L-Homoserine, N-[(1,1-dimethylethoxy)carbonyl]-
  • (S)-2-(Boc-amino)-4-hydroxybutyric Acid
  • (S)-2-(tert-Butoxycarbonylamino)-4-hydroxybutyric Acid
  • N-α-(t-Butoxycarbonyl)-L-homoserine
  • Boc-HoSer
  • Boc-Hse
  • Boc-HSer-OH
  • (tert-butoxy carbonyl)-L-homoserine
  • 41088-86-2
  • Modified Amino Acids
  • A - H
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • BioChemical
  • Amino Acids & Derivatives
  • Amino Acid Derivatives