N-BOC-(R)-1-AMINO-2-PROPANOL

Product Name: N-BOC-(R)-1-AMINO-2-PROPANOL
CAS No.: 119768-44-4
Chemical Name: N-BOC-(R)-1-AMINO-2-PROPANOL
Synonyms: N-Boc-(R)-isopropanolamine;BOC-(R)-1-AMINO-2-PROPANOL;N-BOC-(R)-1-AMINO-2-PROPANOL;(R)-1-(Boc-amino)-2-propanol;BOC-(R)-(-)-1-AMINO-2-PROPANOL;N-T-BOC-(R)-1-AMINO-2-PROPANOL;N-Boc-(R)-2-hydroxypropanamine;(R)-1-(Boc-amino)-2-propanol, 98%;(R)-tert-Butyl 2-hydroxypropylcarbaMate;tert-butyl (R)-2-hydroxypropylcarbamate
CBNumber: CB0463878
Molecular Formula: C8H17NO3
Formula Weight: 175.23
MOL File: 119768-44-4.mol

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N-BOC-(R)-1-AMINO-2-PROPANOL Property

Boiling point:: 276.4±23.0 °C(Predicted)
Density: 1.025±0.06 g/cm3(Predicted)
refractive index: 1.4460
storage temp.: 2-8°C
pka: 12.42±0.46(Predicted)
Appearance: Colorless to light yellow Viscous Liquid
InChI: InChI=1S/C8H17NO3/c1-6(10)5-9-7(11)12-8(2,3)4/h6,10H,5H2,1-4H3,(H,9,11)/t6-/m1/s1
InChIKey: YNJCFDAODGKHAV-ZCFIWIBFSA-N
SMILES: C(OC(C)(C)C)(=O)NC[C@H](O)C
CAS DataBase Reference: 119768-44-4

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Safety

HS Code: 2924297099

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: AAA0001661
Product name: N-T-BOC-(R)-1-AMINO-2-PROPANOL
Purity: 95.00%
Packaging: 1G
Price: $190.05
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50601
Product name: Boc-(R)-1-amino-2-propanol
Packaging: 10g
Price: $128
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50601
Product name: Boc-(R)-1-amino-2-propanol
Packaging: 1g
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50601
Product name: Boc-(R)-1-amino-2-propanol
Packaging: 2g
Price: $64
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB50601
Product name: Boc-(R)-1-amino-2-propanol
Packaging: 5G
Price: $80
Updated: 2021/12/16

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N-BOC-(R)-1-AMINO-2-PROPANOL Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Synthesis

24424-99-5

78-96-6

95656-86-3

Step 1: 1-Amino-2-propanol (compound 42.1; 3.53 g, 47.0 mmol) and triethylamine (25 mL) were dissolved in methanol (35 mL) under nitrogen protection. Subsequently, a solution of di-tert-butyl dicarbonate (10.3 g, 47.0 mmol) in methanol (15 mL) was added slowly and dropwise. The reaction mixture was stirred overnight at room temperature. Upon completion of the reaction, the mixture was concentrated and the residue was dried under high vacuum to give 8.23 g (quantitative yield) of clear oily product. This oily product was dissolved in tetrahydrofuran (100 mL) and triethylamine (13.1 mL, 94.0 mmol) was added. Methanesulfonyl chloride (3.82 mL, 49.3 mmol) was added dropwise to this solution at 0 °C. After 1 h of reaction, the mixture was diluted with ethyl acetate and washed sequentially with 1 M aqueous hydrochloric acid, aqueous sodium bicarbonate and brine. The organic phase was dried with anhydrous sodium sulfate and concentrated to give 10.5 g (88% yield) of a clear oily product (compound 42.2), which solidified on standing. Electrospray mass spectrometry (ES(+)MS) showed m/e = 254 ([M+H]+).

References

[1] Journal of Organic Chemistry, 2000, vol. 65, # 20, p. 6368 - 6380
[2] Patent: US2006/35908, 2006, A1. Location in patent: Page/Page column 108
[3] Patent: US2015/197493, 2015, A1. Location in patent: Paragraph 0744; 0745; 0746
[4] Patent: WO2014/173928, 2014, A1. Location in patent: Page/Page column 52; 53
[5] Patent: WO2006/104356, 2006, A1. Location in patent: Page/Page column 27

N-BOC-(R)-1-AMINO-2-PROPANOL Preparation Products And Raw materials

Raw materials

Preparation Products

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N-BOC-(R)-1-AMINO-2-PROPANOL Suppliers

Canada 1 China 90 Europe 1 Germany 1 India 1 United Kingdom 4 United States 9 Global 107

Amatek Scientific Co. Ltd.

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Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

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View Lastest Price from N-BOC-(R)-1-AMINO-2-PROPANOL manufacturers

Career Henan Chemical Co

Product: N-BOC-(R)-1-AMINO-2-PROPANOL 119768-44-4
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-03

119768-44-4, N-BOC-(R)-1-AMINO-2-PROPANOLRelated Search:

tert-Butyl (2R,3S)-(-)-6-oxo-2,3-diphenyl-4-morpholinecarboxylate BOC-HYP(BZL)-OH Boc-Thr(Bzl)-OH Boc-Hyp-OH N-Boc-trans-4-Hydroxy-L-proline methyl ester BOC-THR(ME)-OH Boc-L-Threonine BOC-(R)-2-AMINO-1-PROPANOL BOC-(S)-2-AMINO-1-PROPANOL 1-(BOC-AMINO)-2-PROPANOL BOC-THR(P-CHLORO-BZL)-OH DCHA (2S,3R)-3-(BOC-AMINO)-2-HYDROXY-4-(4-NITROPHENYL)BUTYRIC ACID BOC-THR(BZL)-ONP BOC-EPI-STATINE BOC-HYP-OH DCHA BOC-HYP-OBZL BOC-THR-OH DCHA N-BOC-(2S,3R)-2-HYDROXY-3-AMINO-4-PHENYLBUTANOIC ACID

N-T-BOC-(R)-1-AMINO-2-PROPANOL

N-BOC-(R)-1-AMINO-2-PROPANOL

BOC-(R)-(-)-1-AMINO-2-PROPANOL

BOC-(R)-1-AMINO-2-PROPANOL

Carbamic acid, [(2R)-2-hydroxypropyl]-, 1,1-dimethylethyl ester (9CI)

(R)-tert-Butyl 2-hydroxypropylcarbaMate

(R)-1-(Boc-amino)-2-propanol, 98%

N-Boc-(R)-2-hydroxypropanamine

tert-butyl [(2R)-2-hydroxypropyl]carbamate

Boc-(R)-1-amino-2-propanol≥ 99% (Assay, Chiral purity)

N-Boc-(R)-isopropanolamine

tert-Butyl (R)-2-hydroxy-1-propylcarbamate

tert-butyl N-[(2R)-2-hydroxypropyl]carbamate

Carbamic acid, N-[(2R)-2-hydroxypropyl]-, 1,1-dimethylethyl ester

tert-butyl (R)-2-hydroxypropylcarbamate

N-[(R)-2-Hydroxypropyl]carbamic acid tert-butyl ester

(R)-1-(Boc-amino)-2-propanol

119768-44-4

N-BOC