ChemicalBook > CAS DataBase List > 1-(BOC-AMINO)-2-PROPANOL

1-(BOC-AMINO)-2-PROPANOL

Product Name
1-(BOC-AMINO)-2-PROPANOL
CAS No.
95656-86-3
Chemical Name
1-(BOC-AMINO)-2-PROPANOL
Synonyms
1-(BOC-AMINO)-2-PROPANOL;tert-Butyl (2-hydroxypropyl)carbaMate;1-(tert-Buoxycarbonyamino)-2-propanol;TERT-BUTYL N-(2-HYDROXYPROPYL)CARBAMATE;1-(TERT-BUTOXYCARBONYLAMINO)-2-PROPANOL;tert-ButylN-(2-Hydroxypropyl)carbamate>N-(2-Hydroxypropyl)carbmic acid tert-Butyl ester;N-(2-HYDROXYPROPYL)CARBAMIC ACID TERT-BUTYL ESTER;(2-Hydroxy-propyl)-carbaMic acid tert-butyl ester;tert-Butyl N-(2-Hydroxypropyl)carbamate
CBNumber
CB9452679
Molecular Formula
C8H17NO3
Formula Weight
175.23
MOL File
95656-86-3.mol
More
Less

1-(BOC-AMINO)-2-PROPANOL Property

Boiling point:
276.4±23.0 °C(Predicted)
Density 
1.02
refractive index 
1.4450-1.4490
storage temp. 
2-8°C
form 
clear liquid
pka
12.42±0.46(Predicted)
color 
Colorless to Light yellow
More
Less

Safety

Hazard Codes 
T
Risk Statements 
25-41
Safety Statements 
26-39
HS Code 
2924.19.8000
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

TCI Chemical
Product number
B2418
Product name
tert-Butyl N-(2-Hydroxypropyl)carbamate
Purity
>98.0%(N)
Packaging
5g
Price
$107
Updated
2025/07/31
TCI Chemical
Product number
B2418
Product name
tert-Butyl N-(2-Hydroxypropyl)carbamate
Purity
>98.0%(N)
Packaging
25g
Price
$350
Updated
2025/07/31
TRC
Product number
B810260
Product name
tert-Butyl N-(2-Hydroxypropyl)carbamate
Packaging
10mg
Price
$45
Updated
2021/12/16
Matrix Scientific
Product number
160520
Product name
tert-Butyl (2-hydroxypropyl)carbamate
Packaging
5g
Price
$160
Updated
2021/12/16
AK Scientific
Product number
V9633
Product name
tert-Butyl N-(2-Hydroxypropyl)carbamate
Packaging
5g
Price
$184
Updated
2021/12/16
More
Less

1-(BOC-AMINO)-2-PROPANOL Chemical Properties,Usage,Production

Synthesis

24424-99-5

78-96-6

95656-86-3

Step 1: 1-Amino-2-propanol (compound 42.1; 3.53 g, 47.0 mmol) and triethylamine (25 mL) were dissolved in methanol (35 mL) under nitrogen protection, and a solution of di-tert-butyl dicarbonate (10.3 g, 47.0 mmol) in methanol (15 mL) was slowly added dropwise. The reaction mixture was stirred at room temperature overnight. Subsequently, the reaction solution was concentrated and the residue was dried under high vacuum to give 8.23 g (quantitative yield) of clear oily product. This oily product was dissolved in tetrahydrofuran (100 mL) and triethylamine (13.1 mL, 94.0 mmol) was added. Methanesulfonyl chloride (3.82 mL, 49.3 mmol) was slowly added dropwise to this solution at 0 °C. After 1 hour of reaction, the reaction mixture was diluted with ethyl acetate and washed sequentially with 1 M aqueous hydrochloric acid, aqueous sodium bicarbonate and saturated saline. The organic phase was dried with anhydrous sodium sulfate and concentrated to give 10.5 g (88% yield) of a clear oily substance (compound 42.2), which solidified after standing. Electrospray mass spectrometry (ES(+)MS) showed m/e = 254 ([M+H]+).

References

[1] Journal of Organic Chemistry, 2000, vol. 65, # 20, p. 6368 - 6380
[2] Patent: US2006/35908, 2006, A1. Location in patent: Page/Page column 108
[3] Patent: US2015/197493, 2015, A1. Location in patent: Paragraph 0744; 0745; 0746
[4] Patent: WO2014/173928, 2014, A1. Location in patent: Page/Page column 52; 53
[5] Patent: WO2006/104356, 2006, A1. Location in patent: Page/Page column 27

1-(BOC-AMINO)-2-PROPANOL Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1-(BOC-AMINO)-2-PROPANOL Suppliers

J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
3B Pharmachem (Wuhan) International Co.,Ltd.
Tel
821-50328103-801 18930552037
Fax
86-21-50328109
Email
3bsc@sina.com
Country
China
ProdList
15838
Advantage
69
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Chengdu HappySyn Pharmaceutical Technology Co., Ltd.
Tel
028-85114309 18982182443
Email
yangli@happysyn.com
Country
China
ProdList
2150
Advantage
55
Shanghai Jian Chao Chemical Technology Co., Ltd.
Tel
150-2103-5486 18017383231
Fax
qq:2817624287
Email
983544897@qq.com
Country
China
ProdList
9342
Advantage
55
TOKYO CHEMICAL INDUSTRY CO., LTD.
Tel
03-36680489
Fax
03-3668-0520
Email
Sales-JP@TCIchemicals.com
Country
Japan
ProdList
28387
Advantage
80
TCI Europe
Tel
320-37350700
Fax
+32 (0)37350701
Email
sales@tcieurope.eu
Country
Europe
ProdList
23671
Advantage
75
TCI AMERICA
Tel
800-4238616
Fax
+1-888-520-1075 / +1-503-283-1987
Email
sales@tciamerica.com
Country
Americas
ProdList
23653
Advantage
75
9ding chemical ( Shanghai) Limited
Tel
4009209199
Fax
86-021-52271987
Email
sales@9dingchem.com
Country
China
ProdList
22514
Advantage
55
More
Less

View Lastest Price from 1-(BOC-AMINO)-2-PROPANOL manufacturers

Career Henan Chemical Co
Product
1-(BOC-AMINO)-2-PROPANOL 95656-86-3
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
200kg
Release date
2018-12-24

95656-86-3, 1-(BOC-AMINO)-2-PROPANOLRelated Search:


  • TERT-BUTYL N-(2-HYDROXYPROPYL)CARBAMATE
  • N-(2-HYDROXYPROPYL)CARBAMIC ACID TERT-BUTYL ESTER
  • 1-(TERT-BUTOXYCARBONYLAMINO)-2-PROPANOL
  • 1-(BOC-AMINO)-2-PROPANOL
  • 1-(tert-Buoxycarbonyamino)-2-propanol
  • N-(2-Hydroxypropyl)carbmic acid tert-Butyl ester
  • (2-Hydroxy-propyl)-carbaMic acid tert-butyl ester
  • 1-(Boc-amino)-2-propanol 1-(tert-Butoxycarbonylamino)-2-propanol N-(2-Hydroxypropyl)carbamic Acid tert-Butyl Ester
  • tert-Butyl (2-hydroxypropyl)carbaMate
  • <i>tert</i>-Butyl <i>N</i>-(2-Hydroxypropyl)carbamate
  • Carbamic acid, (2-hydroxypropyl)-, 1,1-dimethylethyl ester (9CI)
  • tert-ButylN-(2-Hydroxypropyl)carbamate&gt
  • Carbamic acid, N-(2-hydroxypropyl)-, 1,1-dimethylethyl ester
  • 95656-86-3
  • N-BOC