7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

Product Name: 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
CAS No.: 171049-41-5
Chemical Name: 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER
Synonyms: 7-AMINO-2-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE;2-Boc-7-amino-1,2,3,4-tetrahydroisoquinoline;ethyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate;TERT-BUTYL 7-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE;tert-butyl 7-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate;7-Amino-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline;7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-B...;tert-butyl 7-aMino-1,2,3,4-tetrahydroisoquinoline-2-carboxylate;7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER;2(1H)-Isoquinolinecarboxylic acid, 7-amino-3,4-dihydro-, 1,1-dimethylethyl ester
CBNumber: CB4468255
Molecular Formula: C14H20N2O2
Formula Weight: 248.32
MOL File: 171049-41-5.mol

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7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Property

Melting point:: 59-61 °C
Boiling point:: 394.7±42.0 °C(Predicted)
Density: 1.145±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 4.81±0.20(Predicted)
Appearance: Light yellow to light brown Solid

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Safety

Hazard Codes: Xn,N
Risk Statements: 22-50
Safety Statements: 61
RIDADR: UN2811

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: B129595
Product name: tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

TRC

Product number: B129595
Product name: tert-Butyl7-Amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
Packaging: 500mg
Price: $155
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42011
Product name: 2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline
Packaging: 25mg
Price: $50
Updated: 2021/12/16

Ark Pharm

Product number: P000060255
Product name: tert-Butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate
Purity: 97%
Packaging: 250mg
Price: $50
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB42011
Product name: 2-Boc-7-Amino-1,2,3,4-tetrahydroisoquinoline
Packaging: 50mg
Price: $80
Updated: 2021/12/16

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7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Chemical Properties,Usage,Production

Synthesis

171049-42-6

171049-41-5

A mixed solution of 7-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylic acid tert-butyl ester (33.2) (4.4 g, 15.81 mmol) was stirred with a mixed solution of Pd/C (500 mg, 4.69 mmol) in MeOH (100 mL) for 3 h at room temperature in an H2 atmosphere. Upon completion of the reaction, the reaction mixture was filtered to remove the catalyst. The filtrate was concentrated to afford the target product tert-butyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate (33.3) as a yellow liquid (3.8 g, 96.8% yield). The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.48 (s, 9H), 2.71 (t, 2H), 3.58 (s, 4H), 4.47 (s, 2H), 6.44 (s, 1H), 6.52 (dd, 1H), 6.91 (d, 1H).

References

[1] Patent: WO2016/90079, 2016, A1. Location in patent: Paragraph 00538-00539
[2] Patent: WO2009/158426, 2009, A1. Location in patent: Page/Page column 108-109
[3] Patent: US2015/231142, 2015, A1. Location in patent: Paragraph 0670
[4] Patent: US2011/98311, 2011, A1

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Suppliers

China 88 India 1 Ukraine 1 United Kingdom 5 United States 26 Global 121

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View Lastest Price from 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER manufacturers

Career Henan Chemical Co

Product: 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER 171049-41-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200kg
Release date: 2020-01-08

171049-41-5, 7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTERRelated Search:

TERT-BUTYL N-(3-THIENYL)CARBAMATE TERT-BUTYL PROPIOLATE tert-butyl 2-(chloromethyl)-1H-benzimidazole-1-carboxylate TERT-BUTYL 4-(4-FORMYL-1,3-THIAZOL-2-YL)TETRAHYDRO-1(2H)-PYRIDINECARBOXYLATE tert-butyl (4-bromobutyl)carbamate tert-butyl N-[3-[methoxy(methyl)amino]-3-oxopropyl]carbamate (4-IODO-PYRIDIN-3-YL)-CARBAMIC ACID TERT-BUTYL ESTER 4-(4-BROMO-BENZENESULFONYL)-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER TERT-BUTYL 4-BROMOPYRIDIN-2-YLCARBAMATE tert-butyl 4-(2,6-dichloropyridin-4-yl)piperazine-1-carboxylate TERT-BUTYL 6,7-DIHYDROTHIAZOLO[5,4-C]PYRIDINE-5(4H)-CARBOXYLATE TERT-BUTYL 4-AMINO-3-FLUOROPIPERIDINE-1-CARBOXYLATE tert-butyl 6-bromo-2H-pyrido[3,2-b][1,4]oxazine-4(3H)-carboxylate tert-butyl 2-oxo-8-azaspiro[4.5]decane-8-carboxylate 1-(BOC-AMINO)-2-PROPANOL 6-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER tert-Butyl 3-aminobenzylcarbamate 3,4-DIHYDROISOQUINOLINE

2-Boc-7-amino-1,2,3,4-tetrahydroisoquinoline

TERT-BUTYL 7-AMINO-3,4-DIHYDROISOQUINOLINE-2(1H)-CARBOXYLATE

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-BUTYL ESTER

7-AMINO-2-BOC-1,2,3,4-TETRAHYDROISOQUINOLINE

tert-butyl 7-aMino-1,2,3,4-tetrahydroisoquinoline-2-carboxylate

7-Amino-2-(tert-butoxycarbonyl)-1,2,3,4-tetrahydroisoquinoline

ethyl 7-amino-3,4-dihydroisoquinoline-2(1H)-carboxylate

2(1H)-Isoquinolinecarboxylic acid, 7-amino-3,4-dihydro-, 1,1-dimethylethyl ester

tert-butyl 7-amino-3,4-dihydro-1H-isoquinoline-2-carboxylate

7-AMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID TERT-B...

171049-41-5

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