TERT-BUTYL N-(3-THIENYL)CARBAMATE
- Product Name
- TERT-BUTYL N-(3-THIENYL)CARBAMATE
- CAS No.
- 19228-91-2
- Chemical Name
- TERT-BUTYL N-(3-THIENYL)CARBAMATE
- Synonyms
- N-Boc-3-aminothiophene;N-Boc-3-aminothiophene 96%;TERT-BUTYL 3-THIENYLCARBAMATE;N-Boc-3-aminothiophene;TERT-BUTYL N-(3-THIENYL)CARBAMATE;tert-butyl thiophen-3-ylcarbaMate;3-Aminothiophene, N-BOC protected;Tert-butyl N-thiophen-3-ylcarbamate;3-(tert-Butoxycarbonylamino)thiophene;1,1-Dimethylethyl N-3-thienylcarbamate
- CBNumber
- CB3760022
- Molecular Formula
- C9H13NO2S
- Formula Weight
- 199.27
- MOL File
- 19228-91-2.mol
TERT-BUTYL N-(3-THIENYL)CARBAMATE Property
- Melting point:
- 138 °C
- Boiling point:
- 238.1±13.0 °C(Predicted)
- Density
- 1.186±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- 13.70±0.70(Predicted)
- form
- wooly crystalline needles
- color
- Off white to faint lemon
- InChI
- 1S/C9H13NO2S/c1-9(2,3)12-8(11)10-7-4-5-13-6-7/h4-6H,1-3H3,(H,10,11)
- InChIKey
- PRWYQCYSADTIBZ-UHFFFAOYSA-N
- SMILES
- CC(C)(C)OC(=O)Nc1ccsc1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 758302
- Product name
- N-Boc-3-aminothiophene
- Purity
- 96%
- Packaging
- 1g
- Price
- $422
- Updated
- 2026/04/30
- Product number
- 113527
- Product name
- tert-Butyl N-(3-thienyl)carbamate
- Packaging
- 1.00g
- Price
- $354
- Updated
- 2026/05/18
- Product number
- B50370
- Product name
- tert-Butyl thiophen-3-ylcarbamate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $11
- Updated
- 2026/05/06
- Product number
- B50370
- Product name
- tert-Butyl thiophen-3-ylcarbamate
- Purity
- 97%
- Packaging
- 1g
- Price
- $17
- Updated
- 2026/05/06
- Product number
- B50370
- Product name
- tert-Butyl thiophen-3-ylcarbamate
- Purity
- 97%
- Packaging
- 5g
- Price
- $40
- Updated
- 2026/05/06
TERT-BUTYL N-(3-THIENYL)CARBAMATE Chemical Properties,Usage,Production
Synthesis
88-13-1
75-65-0
19228-91-2
Preparative Example U-1: Synthesis of tert-butyl N-(3-thienyl)carbamate. 3-Thiophenecarboxylic acid (2.50 g, 19.5 mmol), diphenylphosphoryl azide (4.62 mL, 21.5 mmol), and triethylamine (3.26 mL, 23.4 mmol) were dissolved in tert-butanol (50 mL). The reaction mixture was stirred under reflux conditions for 3.5 hours. Upon completion of the reaction, the reaction solution was cooled to 0 °C and the reaction was quenched by the addition of water. The reaction mixture was subsequently extracted with ethyl acetate and the organic layers were combined and washed with saturated brine. The organic layer was dried over anhydrous magnesium sulfate and concentrated under reduced pressure to remove the solvent. The residue was purified by silica gel column chromatography (eluent: petroleum ether/ethyl acetate=10:1) to afford tert-butyl N-(3-thienyl)carbamate (3.33 g, 16.7 mmol, 86% yield) as a white solid.1H-NMR (DMSO-d6) δ (ppm): 1.46 (9H, s), 6.97 (1H, d, J=5.2 Hz ), 7.16 (1H, s), 7.38 (1H, m), 9.61 (1H, s).
References
[1] Patent: EP1782811, 2007, A1. Location in patent: Page/Page column 66
[2] Patent: EP1669348, 2006, A1. Location in patent: Page/Page column 74
[3] Journal of Materials Chemistry C, 2017, vol. 5, # 10, p. 2509 - 2512
[4] Patent: US2006/154875, 2006, A1. Location in patent: Page/Page column 7; 11; 12
[5] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 21, p. 5567 - 5571
TERT-BUTYL N-(3-THIENYL)CARBAMATE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from TERT-BUTYL N-(3-THIENYL)CARBAMATE manufacturers
- Product
- tert-Butyl 3-thienylcarbamate 19228-91-2
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-26
- Product
- :TERT-BUTYL N-(3-THIENYL)CARBAMATE 19228-91-2
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 98%-99.9%
- Supply Ability
- 100kg
- Release date
- 2020-01-10