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BOC-THR(ME)-OH

Product Name
BOC-THR(ME)-OH
CAS No.
48068-25-3
Chemical Name
BOC-THR(ME)-OH
Synonyms
BOC-THR(ME);BOC-THR(ME)-OH;Boc-L-Thr(Me)-OH;BOC-O-METHYL-L-THREONINE;BOC-THR(ME)-OH USP/EP/BP;N-Boc-O-Methyl-L-threonine;N-Boc-O-methyl-L-threonine,95%;(Tert-Butoxy)Carbonyl Thr(Me)-OH;O-Methyl-L-threonine, N-BOC protected;N-(tert-butoxycarbonyl)-O-methyl-L-threonine
CBNumber
CB3748587
Molecular Formula
C10H19NO5
Formula Weight
233.26
MOL File
48068-25-3.mol
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BOC-THR(ME)-OH Property

Boiling point:
362.1±37.0 °C(Predicted)
Density 
1.123±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
3.50±0.10(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C10H19NO5/c1-6(15-5)7(8(12)13)11-9(14)16-10(2,3)4/h6-7H,1-5H3,(H,11,14)(H,12,13)/t6-,7+/m1/s1
InChIKey
VWSUOKFUIPMDDX-RQJHMYQMSA-N
SMILES
C(O)(=O)[C@H]([C@H](OC)C)NC(OC(C)(C)C)=O
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Safety

HS Code 
2922500090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P233Keep container tightly closed.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304IF INHALED:

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P340Remove victim to fresh air and keep at rest in a position comfortable for breathing.

P362Take off contaminated clothing and wash before reuse.

P403Store in a well-ventilated place.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
B657418
Product name
Boc-O-Methyl-L-threonine
Packaging
50mg
Price
$60
Updated
2021/12/16
Usbiological
Product number
236634
Product name
Boc-O-methyl-L-threonine
Packaging
250mg
Price
$237
Updated
2021/12/16
SynQuest Laboratories
Product number
4156-1-W1
Product name
O-Methyl-L-threonine, N-Boc protected
Packaging
25g
Price
$245
Updated
2021/12/16
Activate Scientific
Product number
AS33266
Product name
Boc-O-Methyl-L-threonine
Purity
96+%
Packaging
25g
Price
$328
Updated
2021/12/16
Apolloscientific
Product number
OR61332
Product name
O-Methyl-L-threonine,N-BOCprotected
Purity
98%
Packaging
1g
Price
$28
Updated
2021/12/16
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BOC-THR(ME)-OH Chemical Properties,Usage,Production

Uses

Boc-Thr(Me)-OH is a threonine derivative[1].

Synthesis

4144-02-9

24424-99-5

48068-25-3

GENERAL METHOD: O-Methyl-L-threonine (10 g, 75.11 mmol) was dissolved in a solvent mixture of THF (350 mL) and water (350 mL) and cooled to 0 °C. NaHCO3 (18.93 g, 225.32 mmol) and di-tert-butyl dicarbonate (Boc2O, 24.59 g, 112.66 mmol) were added sequentially, and the reaction mixture was gradually warmed to room temperature and stirred for 18 hours. Upon completion of the reaction, the pH was adjusted to 4 with aqueous KHSO4 to quench the reaction, followed by extraction with EtOAc (5 × 150 mL). The organic layers were combined, dried with Na2SO4 and concentrated under reduced pressure. The residue was ground with heptane to afford (2S,3R)-2-((tert-butoxycarbonyl)amino)-3-methoxybutyric acid as a white solid (16.50 g, 94% yield).1H NMR (400 MHz, CDCl3): δ 1.22 (d, 3H), 1.45 (s, 9H), 3.28 (s, 3H), 3.98 (br d, 1H). 4.38 (d, 1H), 5.28 (d, 1H), 10.40-10.60 (br s, 1H).

References

[1] Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144. DOI:10.1080/10408398.2012.708368

BOC-THR(ME)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BOC-THR(ME)-OH Suppliers

Sichuan jiayinglai technology CO.,LTD
Tel
028-64159575
Email
1678230860@qq.com
Country
China
ProdList
6511
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Sichuan Guanghan Bio-Tech Co., Ltd
Tel
+86-28-86127071
Fax
+86-28-86127072
Email
info@sino-produce.com
Country
China
ProdList
406
Advantage
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Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
Country
China
ProdList
42934
Advantage
64
Lavem Chine Pharm Company
Tel
028-62070218 18190869852
Fax
86-28-8527-5264
Email
sales@lavemc.com
Country
China
ProdList
214
Advantage
67
Shanghai Sunway Pharmaceutical Technology Co., Ltd
Tel
18270980682
Fax
021 51613951
Email
mlcheng@sunwaypharm.cn
Country
China
ProdList
8669
Advantage
57
Chengdu Ai Keda Chemical Technology Co., Ltd.
Tel
4008-755-333 18080918076
Fax
028-86757656
Email
800078821@qq.com
Country
China
ProdList
9718
Advantage
55
Beijing HuaMeiHuLiBiological Chemical
Tel
010-56205725
Fax
010-65763397
Email
waley188@sohu.com
Country
China
ProdList
12335
Advantage
58
Shanghai Topbiochem Technology Co., Ltd
Tel
+86-21-60341587
Fax
+86-21-61294319
Email
sales@topbiochem.com
Country
China
ProdList
6175
Advantage
58
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View Lastest Price from BOC-THR(ME)-OH manufacturers

Sichuan Jiaying Lai Technology Co.,LTD
Product
Boc-Thr(me)-OH 48068-25-3
Price
US $1.00/g
Min. Order
1g
Purity
98%
Supply Ability
100KG
Release date
2019-07-22
Career Henan Chemical Co
Product
BOC-THR(ME)-OH 48068-25-3
Price
US $1.00/g
Min. Order
100g
Purity
98%min
Supply Ability
G/KG/T
Release date
2019-12-23

48068-25-3, BOC-THR(ME)-OHRelated Search:


  • BOC-THR(ME)-OH
  • BOC-O-METHYL-L-THREONINE
  • (2S,3R)-2-(tert-butoxycarbonylamino)-3-methoxybutanoic acid
  • O-Methyl-L-threonine, N-BOC protected
  • BOC-THR(ME)
  • Boc-L-Thr(Me)-OH
  • (Tert-Butoxy)Carbonyl Thr(Me)-OH
  • (2S,3R)-3-methoxy-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoic acid
  • N-ALPHA-T-BUTOXYCARBONYL-O-METHYL-L-THREONINE
  • N-Boc-O-Methyl-L-threonine
  • L-Threonine, N-[(1,1-dimethylethoxy)carbonyl]-O-methyl-
  • N-Boc-O-methyl-L-threonine,95%
  • BOC-THR(ME)-OH USP/EP/BP
  • N-(tert-butoxycarbonyl)-O-methyl-L-threonine
  • N-[(1,1-Dimethylethoxy)carbonyl]-O-methyl-L-threonine
  • 48068-25-3