ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

Product Name: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
CAS No.: 33458-26-3
Chemical Name: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
Synonyms: 5118-36-5;EU-006731;NSC643910;SBB016167;NCI60_014903;Oprea1_330764;A0951/0044480;AURORA KA-3499;Maybridge1_006365;BUTTPARK 61\40-96
CBNumber: CB0767606
Molecular Formula: C14H16N2O2S
Formula Weight: 276.35
MOL File: 33458-26-3.mol

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ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Property

Melting point:: 180
Boiling point:: 390.5±52.0 °C(Predicted)
Density: 1.25±0.1 g/cm3(Predicted)
pka: 11.33±0.70(Predicted)
InChIKey: QMFBVGUFEGVPNG-UHFFFAOYSA-N

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933599590

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S170372
Product name: 6-ME-4-PH-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER
Purity: AldrichCPR
Packaging: 50MG
Price: $110
Updated: 2024/03/01

Matrix Scientific

Product number: 061399
Product name: Ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Packaging: 500mg
Price: $315
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029794
Product name: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
Purity: 95.00%
Packaging: 1G
Price: $624.07
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0029794
Product name: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE
Purity: 95.00%
Packaging: 10G
Price: $1176.29
Updated: 2021/12/16

Atlantic Research Chemicals

Product number: ES01233
Product name: Ethyl6-Methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate
Purity: 95%
Packaging: 1gm:
Price: $60.09
Updated: 2021/12/16

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ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Chemical Properties,Usage,Production

Uses

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical and pharmaceutical production process middle.

Synthesis

In a 10-mL round-bottom flask equipped with a condenser, a mixture of the aromatic aldehyde (1 mmol), ethyl acetoacetate (1 mmol), urea or thiourea (1.5 mmol) and [Dsbim]Cl (0.0376 g, 10 mol%) was stirred at 80 °C, and the resulting mixture was kept under continuous stirring for lengths of time as specified in Table 3, with the progress of the reaction was followed by TLC. After completion of the reaction, the mixture was cooled to room temperature, and 3 mL of water was added. The ionic liquid was dissolved in water and filtered for separation of the crude product. The separated product was washed twice with water (2 9 3 mL). For recycling the catalysts, after the solid products were thoroughly washed with water, the water containing the ionic liquid (IL is soluble in water) was evaporated under reduced pressure, and the ionic liquid was recovered and reused. The solid product was purified by a recrystallization procedure in ethanol. All of the desired product(s) were characterized by comparison of their physical data with those of known compounds. Entry: 13 Product: 4m; Yield: 90% Mp: 208-210°C; Lit. Mp: 205-206 [23]°C

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Preparation Products And Raw materials

Raw materials

Preparation Products

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ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE Suppliers

Austria 1 Belgium 1 China 26 Germany 1 Hungary 1 India 1 United Kingdom 4 United States 6 Global 41

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View Lastest Price from ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE manufacturers

Career Henan Chemical Co

Product: ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE 33458-26-3
Price: US $7.00/KG
Min. Order: 25KG
Purity: 99%
Supply Ability: 100TONS
Release date: 2018-07-23

33458-26-3, ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATERelated Search:

5118-36-5

6-ME-4-PH-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

4-methyl-6-phenyl-2-thioxo-3,6-dihydro-1H-pyrimidine-5-carboxylic acid ethyl ester

A0951/0044480

ethyl 4-methyl-6-phenyl-2-sulfanylidene-3,6-dihydro-1H-pyrimidine-5-carboxylate

ethyl 4-methyl-6-phenyl-2-thioxo-3,6-dihydro-1H-pyrimidine-5-carboxylate

EU-006731

Maybridge1_006365

NCI60_014903

NSC643910

Oprea1_330764

Pyrimidine-5-carboxilyc acid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-thioxo-, ethyl ester

SBB016167

5-Pyrimidinecarboxylicacid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-thioxo-, ethyl ester

Ethyl 6-methyl-4-phenyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDRO-5-PYRIMIDINECARBOXYLATE

ETHYL 6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDROPYRIMIDINE-5-CARBOXYLATE

AURORA KA-3499

BUTTPARK 61\40-96

Pyrimidine-5-carboxilyc acid, 1,2,3,4-tetrahydro-6-methyl-4-phenyl-2-t hione-, ethyl ester

6-Methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

6-METHYL-4-PHENYL-2-THIOXO-1,2,3,4-TETRAHYDRO-PYRIMIDINE-5-CARBOXYLIC ACID ETHYL ESTER

5-pyrimidinecarboxylic acid, 1,2,3,4-tetrahydro-6-methyl-4

Ethyl 6-methyl-4-phenyl-2-sulfanylidene-1,2,3,4-tetrahydropyrimidine-5-carboxylate

ethyl 6-methyl-4-phenyl-2-thioxo-1,2,3,4-tetrahydropyrimidin...

33458-26-3