ANTI-KU80
- Product Name
- ANTI-KU80
- Chemical Name
- ANTI-KU80
- Synonyms
- KU80;Ku86;KUB2;NFIV;KARP1;ANTI-KU80;Anti-Ku86;Anti-TLAA;Anti-NFIV;FLJ39089)
- CBNumber
- CB0772725
- Formula Weight
- 0
- MOL File
- Mol file
ANTI-KU80 Property
- storage temp.
- −20°C
- form
- ammonium sulfate suspension
- biological source
- rabbit
N-Bromosuccinimide Price
- Product number
- HPA064685
- Product name
- Anti-XRCC5 antibody produced in rabbit
- Purity
- Prestige Antibodies<SUP>®</SUP> Powered by Atlas Antibodies, affinity isolated antibody
- Packaging
- 100 μL
- Price
- $530
- Updated
- 2025/07/31
- Product number
- HPA025813
- Product name
- Anti-XRCC5 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 100μL
- Price
- $530
- Updated
- 2025/07/31
- Product number
- HPA025813
- Product name
- Anti-XRCC5 antibody produced in rabbit
- Purity
- Prestige Antibodies? Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution
- Packaging
- 25μL
- Price
- $282
- Updated
- 2023/06/20
- Product number
- ATB0014973
- Product name
- ANTI-KU80
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $497.95
- Updated
- 2021/12/16
ANTI-KU80 Chemical Properties,Usage,Production
Uses
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein which is also known as ATP-dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA-binding component of the DNA-dependent protein kinase, and it functions together with the DNA ligase IV-XRCC4 complex in the repair of DNA double-strand break by non-homologous end joining and the completion of V(D)J recombination events. This gene functionally complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and in ability to undergo V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. (provided by RefSeq)
Biological Activity
The gene XRCC5 (X-ray repair cross complementing 5) is mapped to human chromosome 2q35. It is part of the non-homologous end joining double-strand break repair pathway. XRCC5 helps in damage recognition. Mutations in the gene are associated with risk of glioma and chronic obstructive pulmonary disease (COPD). Mutation in it might also be linked with gastric cancer development, particularly in cases of family history. XRCC5 is also involved in alcohol dependence. In addition, it is a part of the OCFRE (osteocalcin (OC) fibroblast growth factor (FGF) response element (FRE))-binding complex, thereby controlling the gene expression of osteocalcin.
ANTI-KU80 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-KU80 Suppliers
- Tel
- 021-60345367 13916550749
- sales@shzbio.com
- Country
- China
- ProdList
- 9965
- Advantage
- 58
- Tel
- 40-15317324578 4008100881
- atcc@sinozhongyuan.com
- Country
- China
- ProdList
- 3344
- Advantage
- 58
- Tel
- 02-400-810-9781 400810978
- sales@zsbio.com
- Country
- China
- ProdList
- 2887
- Advantage
- 58
- Tel
- 46-854595850
- order@atlasantibodies.com
- Country
- China
- ProdList
- 6586
- Advantage
- 58
- Tel
- 21-20338288
- ordercn@merckgroup.com
- Country
- China
- ProdList
- 6394
- Advantage
- 58
- Tel
- 400-9019800
- sales@bioss.com.cn
- Country
- China
- ProdList
- 6102
- Advantage
- 58
- Tel
- 19513720913
- 2708713838@qq.com
- Country
- China
- ProdList
- 4554
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@advtechind.com
- Country
- United States
- ProdList
- 6075
- Advantage
- 58
- Tel
- 15994750751
- Country
- CHINA
- ProdList
- 172
- Advantage
- 58
- Tel
- 17328662120
- Country
- CHINA
- ProdList
- 139
- Advantage
- 58