Tryptophol

Product Name: Tryptophol
CAS No.: 526-55-6
Chemical Name: Tryptophol
Synonyms: 2-(1H-INDOL-3-YL)ETHAN-1-OL;3-(2-HYDROXYETHYL)INDOLE;INDOLE-3-ETHANOL;IEA;Indoleethanol;3-INDOLEETHANOL;B-3-INDOLYLETHANOL;BETA-3-INDOLYLETHANOL;DK803;NSC 3884
CBNumber: CB0782869
Molecular Formula: C10H11NO
Formula Weight: 161.2
MOL File: 526-55-6.mol

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Tryptophol Property

Melting point:: 56-59 °C(lit.)
Boiling point:: 174 °C (2.02527 mmHg)
Density: 1.0840 (rough estimate)
refractive index: 1.5200 (estimate)
Flash point:: 255 °C
storage temp.: Keep in dark place,Sealed in dry,Room Temperature
solubility: methanol: 0.1 g/mL, clear
pka: 15.16±0.10(Predicted)
form: Crystalline Mass, Crystals, Flakes or Powder
color: Off-white to brown
Water Solubility: 10 g/L (20 ºC)
Merck: 14,9798
BRN: 125553
InChIKey: MBBOMCVGYCRMEA-UHFFFAOYSA-N
LogP: 1.280 (est)
CAS DataBase Reference: 526-55-6(CAS DataBase Reference)
NIST Chemistry Reference: 1H-indole-3-ethanol(526-55-6)
EPA Substance Registry System: 1H-Indole-3-ethanol (526-55-6)

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Safety

Hazard Codes: Xi
Safety Statements: 24/25
WGK Germany: 3
RTECS: KL3685000
F: 8
Hazard Note: Irritant
TSCA: Yes
HS Code: 29339990
Toxicity: LD50 intraperitoneal in mouse: 351mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: T90301
Product name: 3-(2-Hydroxyethyl)indole
Purity: 97%
Packaging: 5g
Price: $103
Updated: 2024/03/01

TCI Chemical

Product number: I0030
Product name: 3-Indoleethanol
Purity: >98.0%(GC)
Packaging: 1g
Price: $35
Updated: 2024/03/01

TCI Chemical

Product number: I0030
Product name: 3-Indoleethanol
Purity: >98.0%(GC)
Packaging: 5g
Price: $101
Updated: 2024/03/01

Alfa Aesar

Product number: L02555
Product name: Tryptophol, 97%
Packaging: 1g
Price: $26.65
Updated: 2024/03/01

Alfa Aesar

Product number: L02555
Product name: Tryptophol, 97%
Packaging: 5g
Price: $86
Updated: 2024/03/01

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Tryptophol Chemical Properties,Usage,Production

Chemical Properties

3-(2-Hydroxyethyl)indole [526-55-6], tryptophol, C10H11NO, Mr 161.20, mp 59 ℃, bp 174 ℃, (2 kPa) forms colorless prisms or flakes that are readily soluble in methanol, ethanol, diethyl ether, chloroform, and acetone, soluble in benzene, and slightly soluble in water. It is produced by reacting methyl-1H-indole-3-acetate with lithium aluminum hydride, or through reduction of methyl-1H-indole-3-glyoxylate with sodium borohydride. The antihypertensive Indoramin is produced from tryptophol.

Uses

Tryptophol is a metabolite formed in the liver after disulfiram treatment that induces sleep in humans. It is also a secondary product of alcoholic fermentation.

Uses

Reactant for preparation of:

Inhibitors of the C-terminal domain of RNA polymerase II and their antitumor activities
Anti-HIV-1 agents
Inhibitors of Protein-Protein Interactions
Partial agonists of the serotonin 5-HT1A receptor
Growth hormone secretagogues
Vascular endothelial growth factor (VEGF) inhibitors
A2B adenosine receptor ligands
Potential detoxification inhibitors of the crucifer phytoalexin brassinin
Inhibitors of interleukine 6
Dual binding site acetylcholinesterase inhibitors

Definition

ChEBI: An indolyl alcohol that is ethanol substituted by a 1H-indol-3-yl group at position 2.

Synthesis Reference(s)

Canadian Journal of Chemistry, 42, p. 485, 1964 DOI: 10.1139/v64-070

Purification Methods

Crystallise it from diethyl ether/pet ether, *C6H6, *C6H6/pet ether. The picrate has m 100-101o (from *C6H6). [Beilstein 21 I 218, 21 II 49, 21 III/IV 788, 21/3 V 61.]

Tryptophol Preparation Products And Raw materials

Raw materials

Preparation Products

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Tryptophol Suppliers

Americas 1 Belgium 2 China 229 Europe 4 Germany 5 India 6 Japan 3 Slovakia 1 Switzerland 3 United Kingdom 12 United States 32 USA 1 Global 299

Jiangxi Kingnord Industrial Limited

Tel: 0791-86493591
Fax: +86 791 8649 3642
Email: jeff@kingnord.com
Country: China
ProdList: 43
Advantage: 57

SHENZHEN REISCH BIOTECH CO., LTD

Tel: 0755-0755-28609002 15112530219
Email: 1179151648@qq.com
Country: China
ProdList: 322
Advantage: 58

Jiujiang Huayao Biotechnology Co., Ltd.

Tel: 0792-13970278 13970278471
Email: 36516506@qq.com
Country: China
ProdList: 75
Advantage: 58

J & K SCIENTIFIC LTD.

Tel: 010-82848833 400-666-7788
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006608290; 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40241
Advantage: 62

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

Chembest Research Laboratories Limited

Tel: 021-20908456
Fax: 021-58180499
Email: sales@BioChemBest.com
Country: China
ProdList: 6011
Advantage: 61

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30132
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24539
Advantage: 81

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44751
Advantage: 61

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View Lastest Price from Tryptophol manufacturers

Ouhuang Engineering Materials (Hubei) Co., Ltd

Product: Tryptophol 526-55-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.91%
Supply Ability: 200000
Release date: 2024-04-23

Hebei Duling International Trade Co. LTD

Product: Tryptophol 526-55-6
Price: US $25.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 5000 Ton
Release date: 2023-02-10

Hebei Yanxi Chemical Co., Ltd.

Product: Tryptophol 526-55-6
Price: US $50.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 10000
Release date: 2023-09-21

526-55-6, TryptopholRelated Search:

Indole-3-acetic acid Oxindole Hydroxyethyl starch Ethanol Indole-3-butyric acid Indole Methyl 2-hydroxyethyl cellulose 2-(2-Aminoethylamino)ethanol PIPERACETAZINE (250 MG) Hydroxyethyl Cellulose Indometacin Sodium isethionate 2-(METHYLSULFONYL)ETHANOL TRYPTAMINE HYDROCHLORIDE Tryptamine 5-BENZYLOXYINDOLE-3-ACETIC ACID 5-METHYLINDOLE-3-ACETIC ACID METHYL 3-INDOLYLACETATE

INDOLE-3-ETHANOL

B-3-INDOLEETHANOL

B-3-INDOLYLETHANOL

BETA-3-INDOLYLETHANOL

3-(BETA-HYDROXYETHYL)INDOLE

3-INDOLEETHANOL

2-(1H-INDOL-3-YL)ETHAN-1-OL

2-(1H-INDOL-3-YL)-ETHANOL

2-(3-INDOLE)ETHANOL

3-(2-HYDROXYETHYL)INDOLE

RARECHEM AH BS 0132

TIMTEC-BB SBB003950

TRYPTOTHOL

TRYPTOPHOL

'TRYPTOPHOL'

1H-Indole-3-ethanol

2-(3-Indolylethanol

3-indolyl-ethano

3-Indolylethanol

3-(2-Hydroxyethyl)indole 97%

Color alcohol

NSC 3884

3-(2-Hydroxyethyl)indole Vetec(TM) reagent grade, 97%

3-Indoleethanol 3-(2-Hydroxyethyl)indole beta-3-Indolylethanol 2-(1H-Indol-3-yl)ethan-1-ol

beta-(3-Indole)ethanol

dl-Tryptophanol

Ethanol, 2-indol-3-yl-

Ethanol, 3-indolyl-

IEA

Indoleethanol

3-β-hydroxyethyl in-dole

β-indolylethylalcohol

3-(2-Hydroxyethyl)indole~2-(3-Indolyl)ethanol

beta-indol-3-ylethanol

Tryptophol (Indole-3-ethanol)

TRYPTOPHOL ULTRA-PURE 99.5%

Tryptophol,97%

3-(2-HYDROXYETHYL)INDOLE (TRYPTOPHOL)

Tryptophol, 3-Indoleethanol

TRYPTOPHOL(IEt)

3-(2-Hydroxyethyl)-1H-indole

Tryptophol, 2-(1H-Indol-3-yl)ethan-1-ol

Tryptophol, 97% 5GR

Indole-3-ethanol (Tryptophol),beta-3-Indolylethanol

3-Indoleethanol&gt

ryptophol

Tryptopho

?-indol-3-ylethanol

Tryptophol (6CI)

DK803

526-55-6

Indoles

Simple Indoles

Heterocyclic Building Blocks

Building Blocks

Heterocyclic Compounds

Indoles

Simple Indoles