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C24-PHYTOCERAMIDE

Product Name
C24-PHYTOCERAMIDE
CAS No.
34437-74-6
Chemical Name
C24-PHYTOCERAMIDE
Synonyms
C24-PHYTOCERAMIDE;N-24:0 Phytosphingosine;C24 Phytoceramide (t18:0/24:0);N-TETRACOSANOYL-PHYTOSPHINGOSINE;C24 Phytosphingosine (t18:0/24:0);N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-tetracosanamide;Tetracosanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-
CBNumber
CB0788937
Molecular Formula
C42H85NO4
Formula Weight
668.13
MOL File
34437-74-6.mol
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C24-PHYTOCERAMIDE Property

storage temp. 
Store at -20°C
solubility 
Chloroform:Methanol (5:1): soluble
form 
A solid
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22827
Product name
C24 Phytosphingosine (t18:0/24:0)
Purity
≥98%
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
22827
Product name
C24 Phytosphingosine (t18:0/24:0)
Purity
≥98%
Packaging
5mg
Price
$184
Updated
2024/03/01
AK Scientific
Product number
7680CR
Product name
N-Tetracosanoylphytosphingosine
Packaging
1mg
Price
$147
Updated
2021/12/16
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C24-PHYTOCERAMIDE Chemical Properties,Usage,Production

Description

C24 Phytoceramide (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis.1,2,3 C24 Phytoceramide (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro.4,5 In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytoceramide (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides.6

Definition

ChEBI: N-tetracosanoylphytosphingosine is a phytoceramide compound having a tetracosanoyl group attached to the nitrogen atom. It has a role as a Saccharomyces cerevisiae metabolite. It is a N-(very-long-chain fatty acyl)-sphingoid base and a N-acylphytosphingosine.

References

1. Crossman, M.W., and Hirschberg, C.B. Biosynthesis of phytosphingosine by the rat J. Biol. Chem. 252(16),5815-5819(1977).
2. Omae, F., Miyazaki, M., Enomoto, A., et al. DES2 protein is responsible for phytoceramide biosynthesis in the mouse small intestine Biochem J. 379(Pt. 3),687-695(2004).
3. Mizutani, Y., Kihara, A., and Igarashi, Y. Identification of the human sphingolipid C4-hydroxylase, hDES2, and its up-regulation during keratinocyte differentiation FEBS Lett. 563(1-3),93-97(2004).
4. de Jager, M., Groenink, W., van der Spek, J., et al. Preparation and characterization of a stratum corneum substitute for in vitro percutaneous penetration studies Biochim. Biophys. Acta 1758(5),636-644(2006).
5. Basse, L.H., Groen, D., and Bouwstra, J.A. Permeability and lipid organization of a novel psoriasis stratum corneum substitute Int. J. Pharm. 457(1),275-282(2013).
6. ?kolová, B., Ková?ik, A., Tesa?, O., et al. Phytosphingosine, sphingosine and dihydrosphingosine ceramides in model skin lipid membranes: Permeability and biophysics Biochim. Biophys. Acta 1859(5),824-834(2017).

C24-PHYTOCERAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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C24-PHYTOCERAMIDE Suppliers

China 10 United Kingdom 2 United States 8 Global 20
Yichang Zhongyitai Trading Co., Ltd.
Tel
0717-6449896 13886658719
Fax
0717-6558598
Email
root@zhongyitai.com
Country
China
ProdList
1977
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58
Shanghai Hongye Biotechnology Co. Ltd
Tel
400-9205774
Email
sales@glpbio.cn
Country
China
ProdList
6777
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58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11217
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58
Shanghai Universal Biotech Co.,Ltd
Tel
13774214275
Email
zhouzz@univ-bio.com
Country
China
ProdList
24990
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58
amyjetsci
Tel
027-59626688 18771149750
Email
sales@amyjet.com
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China
ProdList
3003
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58
TargetMol Chemicals Inc.
Tel
4008200310
Email
marketing@tsbiochem.com
Country
China
ProdList
24647
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58
Shaanxi Didu New Material Co., Ltd
Tel
029-81145920 15353716720
Email
1046@dideu.com
Country
China
ProdList
9983
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58
Shanghai Yifei Biotechnology Co. , Ltd.
Tel
021-65675885 18964387627
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customer_service@efebio.com
Country
China
ProdList
11974
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58
SHANGHAI ZZBIO CO., LTD.
Tel
15102117276 19921389125
Email
tech@zzbioco.com
Country
China
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12065
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Shanghai Hao Zhun Biological Technology Co., Ltd.
Tel
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Fax
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Email
info@zzsrm.com
Country
CHINA
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6650
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34437-74-6, C24-PHYTOCERAMIDERelated Search:

Boscalid Neohesperidosyl dihydrochalcone Phytosphingosine

  • C24 Phytosphingosine (t18:0/24:0)
  • N-TETRACOSANOYL-PHYTOSPHINGOSINE
  • C24-PHYTOCERAMIDE
  • N-24:0 Phytosphingosine
  • C24 Phytoceramide (t18:0/24:0)
  • Tetracosanamide, N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-
  • N-[(1S,2S,3R)-2,3-dihydroxy-1-(hydroxymethyl)heptadecyl]-tetracosanamide
  • 34437-74-6
  • C42H85NO4