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Phytosphingosine

Product Name
Phytosphingosine
CAS No.
554-62-1
Chemical Name
Phytosphingosine
Synonyms
4-HYDROXYSPHINGANINE;D-ribo-Phytosphingosine;(2S,3S,4R)-2-aminooctadecane-1,3,4-triol;Salicyl phytosphingosine;Glycolipid;Phytospingosine;4-D-Hydroxysphinganine;hytosphingosine;ViableCare Phyto-S;Phytosphingosine>
CBNumber
CB5289606
Molecular Formula
C18H39NO3
Formula Weight
317.51
MOL File
554-62-1.mol
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Phytosphingosine Property

Melting point:
102 °C
Boiling point:
483.7±40.0 °C(Predicted)
Density 
0.983
vapor pressure 
0.2Pa at 20℃
refractive index 
9 ° (C=1, Pyridine)
storage temp. 
−20°C
solubility 
Soluble in Ethanol (up to 2 mg/ml).
pka
11.91±0.45(Predicted)
form 
White to off-white solid.
color 
White
Water Solubility 
2.6mg/L at 20℃
Stability:
Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month.
InChI
InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
InChIKey
AERBNCYCJBRYDG-KSZLIROESA-N
SMILES
C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
LogP
6.2 at 22℃
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Safety

WGK Germany 
1
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P2795
Product name
Phytosphingosine hydrochloride
Purity
≥98%, from
Packaging
5mg
Price
$393
Updated
2024/03/01
TCI Chemical
Product number
P1765
Product name
Phytosphingosine
Purity
>98.0%(T)
Packaging
1g
Price
$92
Updated
2024/03/01
TCI Chemical
Product number
P1765
Product name
Phytosphingosine
Purity
>98.0%(T)
Packaging
5g
Price
$276
Updated
2024/03/01
Cayman Chemical
Product number
20217
Product name
Phytosphingosine
Purity
≥95%
Packaging
5mg
Price
$39
Updated
2024/03/01
Cayman Chemical
Product number
20217
Product name
Phytosphingosine
Purity
≥95%
Packaging
10mg
Price
$70
Updated
2024/03/01
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Phytosphingosine Chemical Properties,Usage,Production

Description

Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]

Chemical Properties

Off-White Solid

Uses

phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin.

Uses

Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.

Definition

ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+).

Origin

In 1884, chemist J.L.W coined the word phytosphingosine, which was taken from the term “sphingoid”, a major component in all biological membranes. There are four types of sphingoid bases and phytosphingosine is one of them. Phytosphingosine is a widely distributed natural sphingoid base and found in fungi, plants, and animals.

Flammability and Explosibility

Not classified

Veterinary Drugs and Treatments

Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties.

References

1) Fischer et al. (2012), Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria; Antimicrob. Agents Chemother., 56 1157 2) Fischer et al. (2013), Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage; Skin Pharmacol. Physiol., 26 36

Phytosphingosine Preparation Products And Raw materials

Raw materials

Preparation Products

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Phytosphingosine Suppliers

Wuhan Topule
Tel
+86-02787215551 +86-19945035818
Fax
027-87215551
Email
2936752263@qq.com
Country
China
ProdList
7982
Advantage
58
Hubei Kele Fine Chemical Co., Ltd
Tel
027-59101668 19945030958
Fax
027-59101668
Email
2881924765@qq.com
Country
China
ProdList
8140
Advantage
58
Wuhan Augda Biotechnology Co., Ltd
Tel
15071299552
Fax
QQ:262933239
Email
262933239@qq.com
Country
China
ProdList
6883
Advantage
58
Chongqing Chuanchong Technology Co., Ltd
Tel
023-67015921 19522053615
Email
1142568342@qq.com
Country
China
ProdList
18
Advantage
58
Hangzhou Viablife Biotech Co., Ltd.
Tel
0571-88766806 13386527431
Email
sales@viablife.com
Country
China
ProdList
34
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Adamas Reagent, Ltd.
Tel
400-6009262 16621234537
Fax
021-64823266
Email
chenyj@titansci.com
Country
China
ProdList
14103
Advantage
59
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View Lastest Price from Phytosphingosine manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Phytosphingosine 554-62-1
Price
US $35.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
5000kg/Week
Release date
2024-05-07
Hebei Chuanghai Biotechnology Co,.LTD
Product
Phytosphingosine 554-62-1
Price
US $19.00/KG
Min. Order
1KG
Purity
99.%
Supply Ability
50 ton
Release date
2024-08-22
Chongqing Zhihe Biopharmaceutical Co., Ltd.
Product
Ceramides Phytosphingosine transparent oil mixture 554-62-1
Price
US $0.00-0.00/kg
Min. Order
0.10000000149011612kg
Purity
98% HPLC
Supply Ability
20000kgs
Release date
2023-12-18

554-62-1, PhytosphingosineRelated Search:


  • PHYTOSPHINGOSINE HYDROCHLORIDE
  • (2S, 3S, 4R)-2-AMINO-1,3,4-OCTADECANETRIOL 4-HYDROXYSPHINGANINE
  • 4-HYDROXYSPHINGANINE
  • 1,3,4-Octadecanetriol,2-amino-, (2S, 3S, 4R) -
  • (2S,3S,4R)-2-Amino-1,3,4-octadecanetriol
  • (4R)-4-Hydroxysphinganine
  • D-ribo-Phytosphingosine
  • D-threo-Phytosphingosine
  • d-ribo-1,3,4-trihydroxy-2-aminooctadecane
  • (2S,3S,4R)-2-aminooctadecane-1,3,4-triol
  • (2S,3S,4R)-2-azanyloctadecane-1,3,4-triol
  • 4-D-Hydroxysphinganine
  • 4D-Hydroxysphinganine
  • C18-Phytosphingosine
  • D-Ribo-2-aminooctadecane-1,3,4-triol
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  • ribophytosphingosine hydrochloride
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  • 100% Pure Natural Skin Care Cosmetic Grade 98% CAS 554-62-1 Phytosphingosine
  • TIANFU-CHEM - PHYTOSPHINGOSINE
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  • Phytosphingosine, ≥ 98.0%
  • Phytosphingosine Powder
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  • 554-62-1
  • C18H39NO3
  • BioChemical
  • Biochemicals and Reagents
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  • 554-62-1