Phytosphingosine
- Product Name
- Phytosphingosine
- CAS No.
- 554-62-1
- Chemical Name
- Phytosphingosine
- Synonyms
- 4-HYDROXYSPHINGANINE;D-ribo-Phytosphingosine;(2S,3S,4R)-2-aminooctadecane-1,3,4-triol;Salicyl phytosphingosine;Glycolipid;Phytospingosine;4-D-Hydroxysphinganine;Phyto-S;hytosphingosine;ViableCare Phyto-S
- CBNumber
- CB5289606
- Molecular Formula
- C18H39NO3
- Formula Weight
- 317.51
- MOL File
- 554-62-1.mol
Phytosphingosine Property
- Melting point:
- 102 °C
- Boiling point:
- 483.7±40.0 °C(Predicted)
- Density
- 0.983
- vapor pressure
- 0.2Pa at 20℃
- refractive index
- 9 ° (C=1, Pyridine)
- storage temp.
- −20°C
- solubility
- Soluble in Ethanol (up to 2 mg/ml).
- pka
- 11.91±0.45(Predicted)
- form
- White to off-white solid.
- color
- White
- Water Solubility
- 2.6mg/L at 20℃
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month.
- InChI
- InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
- InChIKey
- AERBNCYCJBRYDG-KSZLIROESA-N
- SMILES
- C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
- LogP
- 6.2 at 22℃
Safety
- WGK Germany
- 1
- HS Code
- 29221990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P2795
- Product name
- Phytosphingosine hydrochloride
- Purity
- ≥98%, from
- Packaging
- 5mg
- Price
- $404
- Updated
- 2025/07/31
- Product number
- P1765
- Product name
- Phytosphingosine
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $92
- Updated
- 2025/07/31
- Product number
- P1765
- Product name
- Phytosphingosine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $276
- Updated
- 2025/07/31
- Product number
- 20217
- Product name
- Phytosphingosine
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 20217
- Product name
- Phytosphingosine
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2024/03/01
Phytosphingosine Chemical Properties,Usage,Production
Description
Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]
Chemical Properties
Off-White Solid
Uses
phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin.
Uses
Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.
Definition
ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+).
Origin
In 1884, chemist J.L.W coined the word phytosphingosine, which was taken from the term “sphingoid”, a major component in all biological membranes. There are four types of sphingoid bases and phytosphingosine is one of them. Phytosphingosine is a widely distributed natural sphingoid base and found in fungi, plants, and animals.
Flammability and Explosibility
Not classified
Veterinary Drugs and Treatments
Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties.
References
[1] CAROL L FISCHER. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria.[J]. Antimicrobial Agents and Chemotherapy, 2012: 1157-1161. DOI:10.1128/aac.05151-11
[2] C L FISCHER. Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage.[J]. Skin Pharmacology and Physiology, 2013, 26 1: 36-44. DOI:10.1159/000343175
Phytosphingosine Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Phytosphingosine manufacturers
- Product
- Phytosphingosine 554-62-1
- Price
- US $5.00-0.50/KG
- Min. Order
- 1KG
- Purity
- 99% hplc
- Supply Ability
- 500TONS
- Release date
- 2025-05-08
- Product
- PHYTOSPHINGOSINE 554-62-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- Ceramides Phytosphingosine transparent oil mixture 554-62-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 98% HPLC
- Supply Ability
- 20000kgs
- Release date
- 2023-12-18