Phytosphingosine
- Product Name
- Phytosphingosine
- CAS No.
- 554-62-1
- Chemical Name
- Phytosphingosine
- Synonyms
- 4-HYDROXYSPHINGANINE;D-ribo-Phytosphingosine;(2S,3S,4R)-2-aminooctadecane-1,3,4-triol;Salicyl phytosphingosine;Glycolipid;Phytospingosine;4-D-Hydroxysphinganine;hytosphingosine;ViableCare Phyto-S;Phytosphingosine>
- CBNumber
- CB5289606
- Molecular Formula
- C18H39NO3
- Formula Weight
- 317.51
- MOL File
- 554-62-1.mol
Phytosphingosine Property
- Melting point:
- 102 °C
- Boiling point:
- 483.7±40.0 °C(Predicted)
- Density
- 0.983
- vapor pressure
- 0.2Pa at 20℃
- refractive index
- 9 ° (C=1, Pyridine)
- storage temp.
- −20°C
- solubility
- Soluble in Ethanol (up to 2 mg/ml).
- pka
- 11.91±0.45(Predicted)
- form
- White to off-white solid.
- color
- White
- Water Solubility
- 2.6mg/L at 20℃
- Stability:
- Stable for 1 year from date of purchase as supplied. Solutions in ethanol may be stored at -20°C for up to 1 month.
- InChI
- InChI=1S/C18H39NO3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17(21)18(22)16(19)15-20/h16-18,20-22H,2-15,19H2,1H3/t16-,17+,18-/m0/s1
- InChIKey
- AERBNCYCJBRYDG-KSZLIROESA-N
- SMILES
- C(O)[C@H](N)[C@H](O)[C@H](O)CCCCCCCCCCCCCC
- LogP
- 6.2 at 22℃
Safety
- WGK Germany
- 1
- HS Code
- 29221990
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P2795
- Product name
- Phytosphingosine hydrochloride
- Purity
- ≥98%, from
- Packaging
- 5mg
- Price
- $393
- Updated
- 2024/03/01
- Product number
- P1765
- Product name
- Phytosphingosine
- Purity
- >98.0%(T)
- Packaging
- 1g
- Price
- $92
- Updated
- 2024/03/01
- Product number
- P1765
- Product name
- Phytosphingosine
- Purity
- >98.0%(T)
- Packaging
- 5g
- Price
- $276
- Updated
- 2024/03/01
- Product number
- 20217
- Product name
- Phytosphingosine
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $39
- Updated
- 2024/03/01
- Product number
- 20217
- Product name
- Phytosphingosine
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $70
- Updated
- 2024/03/01
Phytosphingosine Chemical Properties,Usage,Production
Description
Phytosphingosine is a sphingolipid with a hydroxyl group at the C4 position that is found mainly in fungi and plants but also in animals, including humans. It is metabolized to odd-numbered fatty acids with 2-hydroxy palmitic acid as an intermediate. Phytosphingosine dose-dependently induces cell death of CHO cells and inhibits carbachol-induced activation of phospholipase D (PLD) in CHO cells transfected with C. elegans muscarinic acetylcholine receptors. It is essential in the heat stress response in S. cerevisiae. [Matreya, LLC. Catalog No. 1330]
Chemical Properties
Off-White Solid
Uses
phytosphingosine is a sphingolipid that can improve the overall condition of skin and hair. Some sources site anti-microbial and anti-inflammatory properties. Research indicates similar activity to retinoic acid, in which case it may be particularly beneficial for aging and photo-aging skin.
Uses
Phytosphingosine is a natural anti-microbial compound and it is involved in several cellular processes such as cell differentiation and anti-inflammation.
Definition
ChEBI: Phytosphingosine is a sphingoid, an amino alcohol and a triol. It has a role as a Saccharomyces cerevisiae metabolite and a mouse metabolite. It is functionally related to a N-acyl-beta-D-galactosylphytosphingosine and a sphinganine. It is a conjugate base of a phytosphingosine(1+).
Origin
In 1884, chemist J.L.W coined the word phytosphingosine, which was taken from the term “sphingoid”, a major component in all biological membranes. There are four types of sphingoid bases and phytosphingosine is one of them. Phytosphingosine is a widely distributed natural sphingoid base and found in fungi, plants, and animals.
Flammability and Explosibility
Not classified
Veterinary Drugs and Treatments
Phytosphingosine is a unique topical antiseborrheic compound. It is in a class called ceramides which are waxy materials meant to meant to mimic the normal lipid composition of the stratum corneum. It may also have some antiinflammatory and antimicrobial properties.
References
1) Fischer et al. (2012), Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria; Antimicrob. Agents Chemother., 56 1157 2) Fischer et al. (2013), Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage; Skin Pharmacol. Physiol., 26 36
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Raw materials
Preparation Products
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View Lastest Price from Phytosphingosine manufacturers
- Product
- Phytosphingosine 554-62-1
- Price
- US $35.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 5000kg/Week
- Release date
- 2024-05-07
- Product
- PHYTOSPHINGOSINE 554-62-1
- Price
- US $10.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 10 mt
- Release date
- 2024-11-20
- Product
- Ceramides Phytosphingosine transparent oil mixture 554-62-1
- Price
- US $0.00-0.00/kg
- Min. Order
- 0.10000000149011612kg
- Purity
- 98% HPLC
- Supply Ability
- 20000kgs
- Release date
- 2023-12-18