ChemicalBook > CAS DataBase List > 2-AMINO-4-METHOXYCARBONYL BENZOIC ACID

2-AMINO-4-METHOXYCARBONYL BENZOIC ACID

Product Name
2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
CAS No.
85743-02-8
Chemical Name
2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
Synonyms
2-Carboxy-5-(methoxycarbonyl)aniline;2-AMINO-4-METHOXYCARBONYL BENZOIC ACID;2-amino-benzene-1,4-dicarboxylic acid,4-methyl ester;1,4-Benzenedicarboxylic acid, 2-amino-, 4-methyl ester
CBNumber
CB0801928
Molecular Formula
C9H9NO4
Formula Weight
195.17
MOL File
85743-02-8.mol
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2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Property

Melting point:
213 °C
Boiling point:
397.7±32.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2–8 °C
form 
solid
pka
4.51±0.10(Predicted)
color 
Yellow
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Safety

HS Code 
2922498590
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Synthonix
Product number
A51848
Product name
2-Amino-4-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
100mg
Price
$218
Updated
2026/05/06
Synthonix
Product number
A51848
Product name
2-Amino-4-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
250mg
Price
$253
Updated
2026/05/06
Synthonix
Product number
A51848
Product name
2-Amino-4-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
1g
Price
$262
Updated
2026/05/06
Synthonix
Product number
A51848
Product name
2-Amino-4-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
5g
Price
$270
Updated
2026/05/06
ACHEMBLOCK
Product number
M15084
Product name
2-Amino-4-(methoxycarbonyl)benzoic acid
Purity
97%
Packaging
5G
Price
$360
Updated
2026/05/27
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2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Chemical Properties,Usage,Production

Uses

Methyl 3-Amino-4-carboxybenzoate is an intermediate used to prepare (N-methylpiperazinyl)-contg. derivatives of quinazolinone as fungal efflux pump inhibitors.

Synthesis

55737-66-1

85743-02-8

General procedure for the synthesis of 2-amino-4-methoxycarbonylbenzoic acid from methyl 3-nitro-4-carboxybenzoate: preparation Example 12 Step 1. A suspension of 2-amino-4-(methoxycarbonyl)benzoic acid 12BA (4-methoxycarbonyl)-2-nitrobenzoic acid (12A) (10.0 g, 44.4 mmol) with 5% Pd/C (4.0 g) was reacted in a 1. 1 MeOH/H2O (50 mL) were mixed and placed under hydrogenation conditions (H2, 50 psi) for 16 hrs of reaction. Upon completion of the reaction, the mixture was filtered through a Celite pad, washed with MeOH, and the filtrate was concentrated to give the product 12B (6.51 g, yield = 75%). Mass spectral analysis showed MS (M+H) = 196.

References

[1] Patent: WO2012/51036, 2012, A1. Location in patent: Page/Page column 79
[2] Patent: US5541178, 1996, A
[3] Monatshefte fuer Chemie, 1907, vol. 28, p. 822

2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Suppliers

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85743-02-8, 2-AMINO-4-METHOXYCARBONYL BENZOIC ACIDRelated Search:


  • 2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
  • 2-Carboxy-5-(methoxycarbonyl)aniline
  • 2-amino-benzene-1,4-dicarboxylic acid,4-methyl ester
  • 1,4-Benzenedicarboxylic acid, 2-amino-, 4-methyl ester
  • 85743-02-8
  • Esters
  • Phenyls & Phenyl-Het