2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
- Product Name
- 2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
- CAS No.
- 85743-02-8
- Chemical Name
- 2-AMINO-4-METHOXYCARBONYL BENZOIC ACID
- Synonyms
- 2-Carboxy-5-(methoxycarbonyl)aniline;2-AMINO-4-METHOXYCARBONYL BENZOIC ACID;2-amino-benzene-1,4-dicarboxylic acid,4-methyl ester;1,4-Benzenedicarboxylic acid, 2-amino-, 4-methyl ester
- CBNumber
- CB0801928
- Molecular Formula
- C9H9NO4
- Formula Weight
- 195.17
- MOL File
- 85743-02-8.mol
2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Property
- Melting point:
- 213 °C
- Boiling point:
- 397.7±32.0 °C(Predicted)
- Density
- 1.373±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- form
- solid
- pka
- 4.51±0.10(Predicted)
- color
- Yellow
Safety
- HS Code
- 2922498590
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M285850
- Product name
- Methyl3-Amino-4-carboxybenzoate
- Packaging
- 1g
- Price
- $130
- Updated
- 2021/12/16
- Product number
- M285850
- Product name
- Methyl3-Amino-4-carboxybenzoate
- Packaging
- 10g
- Price
- $880
- Updated
- 2021/12/16
- Product number
- 0855AF
- Product name
- 2-Amino-4-(methoxycarbonyl)benzoicacid
- Packaging
- 250mg
- Price
- $126
- Updated
- 2021/12/16
- Product number
- OR40063
- Product name
- 2-Amino-4-(methoxycarbonyl)benzoicacid
- Packaging
- 1g
- Price
- $157
- Updated
- 2021/12/16
- Product number
- 4657-1-48
- Product name
- 2-Amino-4-(methoxycarbonyl)benzoic acid
- Packaging
- 1g
- Price
- $173
- Updated
- 2021/12/16
2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Chemical Properties,Usage,Production
Uses
Methyl 3-Amino-4-carboxybenzoate is an intermediate used to prepare (N-methylpiperazinyl)-contg. derivatives of quinazolinone as fungal efflux pump inhibitors.
Synthesis
55737-66-1
85743-02-8
General procedure for the synthesis of 2-amino-4-methoxycarbonylbenzoic acid from methyl 3-nitro-4-carboxybenzoate: preparation Example 12 Step 1. A suspension of 2-amino-4-(methoxycarbonyl)benzoic acid 12BA (4-methoxycarbonyl)-2-nitrobenzoic acid (12A) (10.0 g, 44.4 mmol) with 5% Pd/C (4.0 g) was reacted in a 1. 1 MeOH/H2O (50 mL) were mixed and placed under hydrogenation conditions (H2, 50 psi) for 16 hrs of reaction. Upon completion of the reaction, the mixture was filtered through a Celite pad, washed with MeOH, and the filtrate was concentrated to give the product 12B (6.51 g, yield = 75%). Mass spectral analysis showed MS (M+H) = 196.
References
[1] Patent: WO2012/51036, 2012, A1. Location in patent: Page/Page column 79
[2] Patent: US5541178, 1996, A
[3] Monatshefte fuer Chemie, 1907, vol. 28, p. 822
2-AMINO-4-METHOXYCARBONYL BENZOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
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