2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

Product Name: 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
CAS No.: 2320560-36-7
Chemical Name: 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
Synonyms: 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)
CBNumber: CB08054649
Molecular Formula: C26H38N6O14
Formula Weight: 658.62
MOL File: 2320560-36-7.mol

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2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Property

solubility: Soluble in DCM

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-24336
Product name: 2-(Azido-PEG3-amido)-1,3-bis(NHSEster)
Purity: 98%
Packaging: 25mg
Price: $350
Updated: 2021/12/16

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2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Chemical Properties,Usage,Production

Description

2-(Azido-PEG3-amido)-1,3-bis(NHS Ester) is a branched PEGylation reagent. The azide groups enable PEGylation via Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, amine-modified oligonucleotides, and other amine-containing molecules. The PEG spacer allows for enhanced hydrophilic properties.

Uses

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. 2-(Azido-PEG3-amido)-1,3-bis(NHS ester) is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs; Alkyl/ether

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Preparation Products And Raw materials

Raw materials

Preparation Products

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2-(Azido-PEG3-amido)-1,3-bis(NHS ester) Suppliers

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2320560-36-7, 2-(Azido-PEG3-amido)-1,3-bis(NHS ester)Related Search:

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2-(Azido-PEG3-amido)-1,3-bis(NHS ester)

2320560-36-7