Cendakimab

Product Name: Cendakimab
CAS No.: 2151032-62-9
Chemical Name: Cendakimab
Synonyms: Cendakimab;Cendakimab (anti-IL-13);Research Grade Cendakimab
CBNumber: CB08081137
Formula Weight: 0
MOL File: Mol file

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Cendakimab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Cendakimab Chemical Properties,Usage,Production

Uses

Cendakimab (RPC4046; ABT 308; CC-93538) is a selective, humanized, recombinant monoclonal antibody against the IL-13 molecule. Cendakimab has a high affinity and potency for both human wild-type and variant IL-13 and blocks binding of IL-13 to both IL-13Rα1 and IL-13Rα2 with IC50s of 352 pM and 631 pM by ELISA, respectively. Cendakimab recognizes both wild-type human IL-13 and the common polymorphic variant R110Q, with binding affinities of 52 and 50 pM, respectively. Cendakimab has the potential for IL-13-related allergic/inflammatory diseases (e.g., asthma and eosinophilic esophagitis)[1].

IC 50

IL-13

References

[1] Catherine S Tripp, et al. RPC4046, A Novel Anti-interleukin-13 Antibody, Blocks IL-13 Binding to IL-13 α1 and α2 Receptors: A Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation First-in-Human Study. Adv Ther. 2017 Jun;34(6):1364-1381. DOI:10.1007/s12325-017-0525-8

Cendakimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Cendakimab Suppliers

China 17 United States 1 Global 18

BOC Sciences

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2151032-62-9, CendakimabRelated Search:

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Cendakimab

Research Grade Cendakimab

Cendakimab (anti-IL-13)

2151032-62-9