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NF110

Product Name
NF110
CAS No.
111150-22-2
Chemical Name
NF110
Synonyms
NF110;4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonicacidtetrasodiumsalt;4-[[3-[[3,5-bis[(4-sulfonatophenyl)carbamoyl]phenyl]carbamoylamino]-5-[(4-sulfonatophenyl)carbamoyl]benzoyl]amino]benzenesulfonate
CBNumber
CB0838926
Molecular Formula
C41H28N6O17S4.4Na
Formula Weight
1096.92
MOL File
111150-22-2.mol
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NF110 Property

storage temp. 
Desiccate at RT
form 
Powder
color 
White to off-white
Water Solubility 
Soluble to 40 mM in water
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
2548
Product name
NF110
Packaging
10
Price
$217
Updated
2021/12/16
Tocris
Product number
2548
Product name
NF110
Packaging
50
Price
$872
Updated
2021/12/16
TRC
Product number
N392503
Product name
NF110
Packaging
10mg
Price
$145
Updated
2021/12/16
TRC
Product number
N392503
Product name
NF110
Packaging
25mg
Price
$295
Updated
2021/12/16
Usbiological
Product number
255971
Product name
NF 110
Packaging
10mg
Price
$466
Updated
2021/12/16
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NF110 Chemical Properties,Usage,Production

Uses

NF 110 is a potent P2X3 receptor antagonist.

Biological Activity

High affinity P2X 3 receptor antagonist (K i values are 36, 82 and 4144 nM for P2X 3 , P2X 1 and P2X 2 recombinant receptors respectively). Shows no activity at P2Y 1 , P2Y 2 and P2Y 11 receptors (IC 50 > 10 μ M). Potently inhibits α , β -meATP-evoked desensitizing currents in rat DRG neurons (IC 50 = 527 nM). Shows antitumor activity against several tumor types.

storage

Desiccate at RT

NF110 Preparation Products And Raw materials

Raw materials

Preparation Products

111150-22-2, NF110Related Search:


  • NF110
  • 4,4',4'',4'''-[Carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakisbenzenesulfonicacidtetrasodiumsalt
  • 4-[[3-[[3,5-bis[(4-sulfonatophenyl)carbamoyl]phenyl]carbamoylamino]-5-[(4-sulfonatophenyl)carbamoyl]benzoyl]amino]benzenesulfonate
  • 111150-22-2
  • C41H28N6Na4O17S4