Sodium formaldehydesulfoxylate dihydrate

Product Name: Sodium formaldehydesulfoxylate dihydrate
CAS No.: 6035-47-8
Chemical Name: Sodium formaldehydesulfoxylate dihydrate
Synonyms: RONGALITE;SODIUM FORMALDEHYDE SULFOXYLATE;SODIUM FORMALDEHYDE SULPHOXYLATE;SODIUM HYDROXYMETHANESULFINATE DIHYDRATE;RONGALITE C;SODIUM FORMALDEHYDESULFOXALATE;RONGALIT;SODIUM HYDROXYMETHYLSULFINATE;Sodium sulfinomethanolate dihydrate;HYDROXYMETHANESULFINIC ACID SODIUM SALT
CBNumber: CB0853952
Molecular Formula: CH7NaO4S
Formula Weight: 138.11
MOL File: 6035-47-8.mol

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Sodium formaldehydesulfoxylate dihydrate Property

Melting point:: 64-68 °C(lit.)
Density: 1.8 g/cm3 (20℃)
vapor pressure: 2.68 hPa (20 °C)
storage temp.: Store below +30°C.
solubility: alcohol: slightly soluble(lit.)
form: powder to crystal
color: White to Almost white
PH: 9.5-10.5 (100g/l, H2O, 20℃)
CAS DataBase Reference: 6035-47-8(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 31-68
Safety Statements: 24/25-36/37
WGK Germany: 3
RTECS: PB0390000
HS Code: 28311000
Toxicity: LD50 orally in Rabbit: 6400 mg/kg

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H341Suspected of causing genetic defects

Precautionary statements

P201Obtain special instructions before use.

P308+P313IF exposed or concerned: Get medical advice/attention.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 8.06455
Product name: Sodium formaldehydesulfoxylate hydrate
Purity: (stabilisedwithsodiumcarbonate)forsynthesis
Packaging: 100g
Price: $35.5
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.06455
Product name: Sodium formaldehydesulfoxylate hydrate
Purity: (stabilisedwithsodiumcarbonate)forsynthesis
Packaging: 1kg
Price: $53
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.06455
Product name: Sodium formaldehydesulfoxylate hydrate
Purity: (stabilisedwithsodiumcarbonate)forsynthesis
Packaging: 5kg
Price: $263
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.06455
Product name: Sodium formaldehydesulfoxylate hydrate
Purity: (stabilisedwithsodiumcarbonate)forsynthesis
Packaging: 25kg
Price: $476
Updated: 2024/03/01

Sigma-Aldrich

Product number: 8.06455
Product name: Sodium formaldehydesulfoxylate hydrate
Purity: (stabilisedwithsodiumcarbonate)forsynthesis
Packaging: 50kg
Price: $928
Updated: 2024/03/01

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Sodium formaldehydesulfoxylate dihydrate Chemical Properties,Usage,Production

Chemical Properties

white crystalline powder

Chemical Properties

When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.

Uses

Pharmaceutic aid (preservative).

Uses

Sodium hydroxymethanesulfinate dihydrate is a versatile reagent that can be used for a wide range of organic transformations such as:

A SO₂^-2anion source for the preparation of sulfones and sultines.
Debromination of vicinal dibromoalkanes.
Reductive dehalogenation of aldehydes and ketones.

Production Methods

Sodium formaldehyde sulfoxylate is manufactured from sodium dithionate and formaldehyde in water.

General Description

Oxidation reation of hydroxymethanesulfinic acid with chlorite has been studied in the pH range 4-8. It is a sulfur-containing reducing agent.

Pharmaceutical Applications

Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate. It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

Safety

The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient.
Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.
LD50 (mouse, oral): 4 g/kg
LD50 (rat, IP): >2 g/kg
LD50 (rat, oral): >2 g/kg

storage

Store in well-closed, light-resistant containers at controlled room temperature (15–30℃).

Incompatibilities

Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.

Regulatory Status

Included in the FDA Inactive Ingredients Database (parenteral products up to 0.1% via the IM, IV, and SC routes). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

Sodium formaldehydesulfoxylate dihydrate Preparation Products And Raw materials

Raw materials

ZINC HYDROSULFITE

Preparation Products

Neoarsphenamine microdispersoid acrylate resin filling emulsion

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Sodium formaldehydesulfoxylate dihydrate Suppliers

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View Lastest Price from Sodium formaldehydesulfoxylate dihydrate manufacturers

Wuxi High Mountain Hi-tech Development Co.,Ltd.

Product: Sodium Formaldehyde Sulphoxylate 6035-47-8
Price: US $50.00-2000.00/kg
Min. Order: 1000kg
Purity: 98% min, 99% min
Supply Ability: 5000MT per year
Release date: 2024-12-26

Hebei Zhuanglai Chemical Trading Co Ltd

Product: Sodium formaldehydesulfoxylate dihydrate 6035-47-8
Price: US $45.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20 tons
Release date: 2024-12-19

Hebei Weibang Biotechnology Co., Ltd

Product: Sodium formaldehydesulfoxylate dihydrate 6035-47-8
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2024-11-15

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