Ethylhexylglycerin
Description Chemical Properties Uses Safety Toxicity evaluation Reference- Product Name
- Ethylhexylglycerin
- CAS No.
- 70445-33-9
- Chemical Name
- Ethylhexylglycerin
- Synonyms
- Ethylhexyl Glecerine;3-(2-ethylhexyloxy)propane-1,2-diol;Sensiva SC 50;Ethylhexylglycerine;Ethyl hexyl glycerol;Lexgard E;3-[2-(EthyL;liquid,100Ml;OCTOXYGLYCERIN;Octoxyglycerol
- CBNumber
- CB0854782
- Molecular Formula
- C11H24O3
- Formula Weight
- 204.31
- MOL File
- 70445-33-9.mol
Ethylhexylglycerin Property
- Boiling point:
- 325°C
- Density
- 0.962
- refractive index
- 1.4490 to 1.4530
- Flash point:
- 152°C(lit.)
- storage temp.
- Sealed in dry,Room Temperature
- solubility
- Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
- form
- Oil
- pka
- 13.67±0.20(Predicted)
- color
- Colourless
- Odor
- Characteristic
- InChI
- InChI=1S/C11H24O3/c1-3-5-6-10(4-2)8-14-9-11(13)7-12/h10-13H,3-9H2,1-2H3
- InChIKey
- NCZPCONIKBICGS-UHFFFAOYSA-N
- SMILES
- C(O)C(O)COCC(CC)CCCC
- LogP
- 2.470 (est)
- CAS DataBase Reference
- 70445-33-9
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H318Causes serious eye damage
H412Harmful to aquatic life with long lasting effects
- Precautionary statements
-
P273Avoid release to the environment.
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- E1044
- Product name
- 3-(2-Ethylhexyloxy)-1,2-propanediol
- Purity
- >98.0%(GC)
- Packaging
- 25mL
- Price
- $87
- Updated
- 2024/03/01
- Product number
- E918770
- Product name
- 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol
- Packaging
- 1g
- Price
- $185
- Updated
- 2021/12/16
- Product number
- 5971AL
- Product name
- 3-[2-(Ethylhexyl)oxyl]-1,2-propandiol
- Packaging
- 25g
- Price
- $107
- Updated
- 2021/12/16
- Product number
- OR942257
- Product name
- 3-(2-Ethylhexoxy)propane-1,2-diol
- Packaging
- 250g
- Price
- $167
- Updated
- 2021/12/16
- Product number
- OR942257
- Product name
- 3-(2-Ethylhexoxy)propane-1,2-diol
- Packaging
- 1Kg
- Price
- $377
- Updated
- 2021/12/16
Ethylhexylglycerin Chemical Properties,Usage,Production
Description
Ethylhexylglycerin is also named as 3-(2-Ethylhexoxy)propane-1,2-diol or octoxyglycerin. It is a glyceryl ether. It is used as a weak preservative, as skin conditioning agent with effective wetting ability. It is used with phenoxyethanol in cosmetics to obtain better protection against microbial growth.
Chemical Properties
Ethylhexylglycerin is a glycerol monoalkylether of defined structure and high purity,with a 2-ethylhexyl group bound to the primary hydroxyl function of the glycerol molecule. Due to the fact that it is a crystal-clear,colourless liquid with a slightly characteristic odour it is well suited for the use in cosmetic products. Although it is less soluble in water(<0.1% at 25℃),it is more easily soluble in most common cosmetic alcohols and glycols as well as oils.Ethylhexylglycerin is rather stable, e.g. against hydrolysis and elevated temperatures and compatible with cosmetic ingredients.
Ethylhexylglycerin is globally approved and as a new substance accords with the European legislation listed on the ELINCS file.
International Approvals
Europe / USA: INCl name: Ethylhexylglycerin
Australia: AICS/NICNAS(NA/966)，TGA
Canada:DSL
Japan:
ENCS as glycerin monoalkyl(or alkenyl,C8-C24)ether(No.: 2-414)
CLS 199
Uses
Ethylhexylglycerin is a natural preservative, used as an alternative to parabens products. It is derived from natural glycerin. Also used as a deodorizer and skin conditioner.
Ethylhexylglycerin is a glyceryl ether and serves as an emollient solvent and a fixative with antimicrobial properties, and it is reported to enhance uptake of preservatives in microorganisms. It is often used as an alternative to parabens. The International Nomenclature of Cosmetic Ingredients name is Ethylhexylglycerin, and the chemical formula and synonym names are shown in Figure 1. Ethylhexylglycerin is a colorless to pale viscous liquid. It is reported to be used at a concentration up to 2% in leave-on products and 8% in rinse-off products. It is manufactured and marketed by Schu¨lke & Mayr GMBH, Norderstedt, Germany, under the trade name, Sensiva SC50, which is greater than 99% pure. Ethylhexylglycerin is found in many cosmetic products, that is, antiaging creams, sunscreens, eye shadows, eye creams, lip gloss, deodorants, facial moisturizers, and various types of cleansers.
Safety
With an EWG score of 1 and a rating of GOOD from Paula’s Choice, ethylhexylgylcerin is deemed to be very safe and a non-irritant.
Ethylhexylglycerin is a topical skin care ingredient and deodorizing agent, often indicated as a conditioning ointment in the treatment of eczema. It can also be a surfactant and preservative-enhancer and can be found as a substituent for parabens. Ethylhexylglycerin is commonly found in baby products or cosmetics marketed as “hypoallergenic” or “formaldehyde free”.
Ethylhexylglycerin has been reported to cause dermatitis and skin irritation.
www.cir-safety.org
What Is Ethylhexylglcerin & Is It Safe?
Toxicity evaluation
The oral toxicity of ethylhexylglycerin (Sensiva® SC 50, in polyethylene glycol 400) at doses of 100, 500, and 1,500 mg/kg was evaluated in a 28-day study using groups of 10 rats of an unspecified strain. The test substance was administered at a dose volume of 5 ml/kg.There were no treatment-related mortalities. Body weight development was retarded in mid- and high-dose groups, and this finding was accompanied by a non-statistically significant reduction in food intake when compared to the control (polyethylene glycol 400) group. Both eye and ear functions remained unchanged during the study, and increased salivation (dose not stated) was the only clinical symptom observed. Hematological parameters were unaffected by treatment; however, serum analyses indicated changes in aminotransferase (above normal) in high-dose rats. Urinalysis and necropsy findings were unremarkable.
Reference
W. Beilfuss, M. Leschke, K. Weber, A New Concept to Boost the Preservative Efficacy of Phenoxyethanol, SÖFW-Journal, 2005, vol. 131
Uses
Ethylhexylglycerin is the novel raw material for deodorants application and is widely used as a cosmetic emollient. Ethylhexylglycerin reliably inhibits the odor-causing bacteria, yeast and fungi on the skin.
Contact allergens
This glycerol monoalkylether is used as a skin conditioning agent, with bactericidal properties against Gram-positive bacteria.
Synthesis
Synthesis of ethylhexylglycerin is via the catalytic splitting of ethylhexylglycidyl ether followed by the addition of water. The product can then be purified by vacuum distillation.
Ethylhexylglycerin Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Ethylhexylglycerin manufacturers
- Product
- Octoxyglycerin 70445-33-9
- Price
- US $18.00-18.00/kg
- Min. Order
- 1kg
- Purity
- 99.9
- Supply Ability
- 5000
- Release date
- 2024-05-11
- Product
- Octoxyglycerin 70445-33-9
- Price
- US $60.00/kg
- Min. Order
- 1kg
- Purity
- 99
- Supply Ability
- 5000
- Release date
- 2024-05-10
- Product
- Ethylhexylglycerin 70445-33-9
- Price
- US $6.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 20TONS
- Release date
- 2024-05-07